Search Results - "Arijs, I."
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Monocyte-driven atypical cytokine storm and aberrant neutrophil activation as key mediators of COVID-19 disease severity
Published in Nature communications (05-07-2021)“…Epidemiological and clinical reports indicate that SARS-CoV-2 virulence hinges upon the triggering of an aberrant host immune response, more so than on direct…”
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Mucosal gene signatures to predict response to infliximab in patients with ulcerative colitis
Published in Gut (01-12-2009)“…Infliximab is an effective treatment for ulcerative colitis with over 60% of patients responding to treatment and up to 30% reaching remission. The mechanism…”
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Long-term outcome of treatment with infliximab in 614 patients with Crohn's disease: results from a single-centre cohort
Published in Gut (01-04-2009)“…This observational study assessed the long-term clinical benefit of infliximab (IFX) in 614 consecutive patients with Crohn's disease (CD) from a single centre…”
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Antimicrobial Prophylaxis in Transurethral Resection of the Prostate: Results of a Randomized Trial
Published in The Journal of urology (01-06-2021)“…We sought to determine whether omitting antimicrobial prophylaxis is safe in patients undergoing transurethral resection of the prostate without preoperative…”
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A randomized trial regarding antimicrobial prophylaxis (AMP) in transurethral resection of bladder tumor (TURB)
Published in World journal of urology (01-10-2021)“…Purpose To determine whether omitting antimicrobial prophylaxis (AMP) in TURB is safe in patients undergoing TURB without an indwelling pre-operative…”
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Antibiotic prophylaxis in TURP: a prospective analysis concerning antibiotic stewardship and a potential reduction of antibiotic use in TURP
Published in World journal of urology (01-11-2019)“…Purpose Antibiotic prophylaxis is standard procedure in transurethral resection of the prostate (TURP). We evaluated the necessity of antibiotic (AB)…”
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Faecal metabolite profiling identifies medium-chain fatty acids as discriminating compounds in IBD
Published in Gut (01-03-2015)“…Bacteria play a role in the onset and perpetuation of intestinal inflammation in IBD. Compositional alterations may also change the metabolic capacities of the…”
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Mucosal healing predicts long‐term outcome of maintenance therapy with infliximab in Crohn's disease
Published in Inflammatory bowel diseases (01-09-2009)“…Background: Infliximab (IFX) treatment induces mucosal healing (MH) in patients with Crohn's disease (CD) but the impact of MH on the long‐term outcome of IFX…”
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Identification, validation and biological characterisation of novel glioblastoma tumour microenvironment subtypes: implications for precision immunotherapy
Published in Annals of oncology (01-03-2023)“…New precision medicine therapies are urgently required for glioblastoma (GBM). However, to date, efforts to subtype patients based on molecular profiles have…”
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Specific members of the predominant gut microbiota predict pouchitis following colectomy and IPAA in UC
Published in Gut (01-01-2017)“…Pouchitis is the most common complication after colectomy with ileal pouch-anal anastomosis (IPAA) for UC and the risk is the highest within the 1st year after…”
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Mucosal gene expression of antimicrobial peptides in inflammatory bowel disease before and after first infliximab treatment
Published in PloS one (24-11-2009)“…Antimicrobial peptides (AMPs) protect the host intestinal mucosa against microorganisms. Abnormal expression of defensins was shown in inflammatory bowel…”
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P347 Practical recommendations for the collection of the patient-reported outcomes included in the Health Outcomes Observatory (H2O) core data set for patients with inflammatory bowel disease
Published in Journal of Crohn's and colitis (30-01-2023)“…Abstract Background Large scale data integration and comparison require standardised data collection. As part of the Health Outcomes Observatory (H2O) project,…”
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A Core Outcome Set for Inflammatory Bowel Diseases: Development and Recommendations for Implementation in Clinical Practice Through an International Multi-stakeholder Consensus Process
Published in Journal of Crohn's and colitis (15-10-2024)“…Abstract Background and Aims Standardising health outcome measurements supports delivery of care and enables data-driven learning systems and secondary data…”
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P005 A multi-marker serum test to assess the presence of ulcerations in infliximab treated patients with Crohn’s disease
Published in Journal of Crohn's and colitis (16-01-2018)“…Abstract Background Resolution of ulcerations is an important component of mucosal healing (MH) in Crohn’s disease (CD) that is typically assessed with…”
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Biopsy-derived Intestinal Epithelial Cell Cultures for Pathway-based Stratification of Patients With Inflammatory Bowel Disease
Published in Journal of Crohn's and colitis (24-01-2018)“…Abstract Background Endoplasmic reticulum [ER] stress was shown to be pivotal in the pathogenesis of inflammatory bowel disease. Despite progress in…”
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P035 TNF-driven pathways are increased at baseline in Crohn's disease patients not responding to infliximab
Published in Journal of Crohn's and colitis (01-02-2017)Get full text
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P095 The genetic risk in ER stress and autophagy translates into quantifiable epithelial ER stress levels in IBD patients
Published in Journal of Crohn's and colitis (01-02-2017)Get full text
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