Search Results - "Arii, Shigeki"
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1
Molecularly targeted therapy for hepatocellular carcinoma
Published in Cancer science (01-01-2009)“…Accumulated understanding of the molecular pathways regulating cancer progression has led to the development of novel targeted therapies. Hepatocellular…”
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2
Molecular Targeted Therapies in Hepatocellular Carcinoma
Published in Seminars in oncology (01-08-2012)“…In vivo tumor progression requires the supply of oxygen and nutrition by neovasculature. Hepatocellular carcinoma (HCC) is one of the typical tumors with…”
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3
miR-124 and miR-203 are epigenetically silenced tumor-suppressive microRNAs in hepatocellular carcinoma
Published in Carcinogenesis (New York) (01-05-2010)“…MicroRNAs (miRNAs) are a class of small non-coding RNAs that, in general, negatively regulate gene expression. They have been identified in various tumor…”
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4
Evidence-based Clinical Practice Guidelines for Hepatocellular Carcinoma: The Japan Society of Hepatology 2013 update (3rd JSH-HCC Guidelines)
Published in Hepatology research (01-02-2015)“…The 3rd version of Clinical Practice Guidelines for Hepatocellular Carcinoma was revised by the Japan Society of Hepatology, according to the methodology of…”
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5
The tumor-suppressive miR-497-195 cluster targets multiple cell-cycle regulators in hepatocellular carcinoma
Published in PloS one (27-03-2013)“…MicroRNAs (miRNAs) are key post-transcriptional regulators of gene expression and commonly deregulated in carcinogenesis. To explore functionally crucial…”
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6
Molecular targeted therapy for hepatocellular carcinoma in the current and potential next strategies
Published in Journal of gastroenterology (01-03-2011)“…Hepatocellular carcinoma (HCC) is one of the most common malignancies worldwide and its incidence is still increasing. While the primary curative treatment for…”
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Report of the 17th Nationwide Follow-up Survey of Primary Liver Cancer in Japan
Published in Hepatology research (01-09-2007)“…In the 17th Nationwide Follow‐up Survey of Primary Liver Cancer in Japan, 18 213 individuals were newly registered as patients with primary liver cancer at 645…”
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8
Development of evidence‐based clinical guidelines for the diagnosis and treatment of hepatocellular carcinoma in Japan
Published in Hepatology research (01-01-2008)“…The Clinical Practice Guidelines for Hepatocellular Carcinoma (HCC), the first evidence‐based guidelines for the treatment of HCC in Japan, were compiled by an…”
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9
Management of hepatocellular carcinoma: Report of Consensus Meeting in the 45th Annual Meeting of the Japan Society of Hepatology (2009)
Published in Hepatology research (01-07-2010)“…Hepatocellular carcinoma (HCC) is responsible for approximately 600 000–700 000 deaths worldwide. It is highly prevalent in the Asia–Pacific region and Africa,…”
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10
Superselective transarterial chemoembolization for hepatocellular carcinoma. Validation of treatment algorithm proposed by Japanese guidelines
Published in Journal of hepatology (01-04-2012)“…Background & Aims Transcatheter arterial chemoembolization with lipiodol (TACE) is widely performed in patients with hepatocellular carcinoma (HCC) unsuitable…”
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11
Comparison of the outcomes between an anatomical subsegmentectomy and a non-anatomical minor hepatectomy for single hepatocellular carcinomas based on a Japanese nationwide survey
Published in Surgery (01-04-2008)“…Background Although a surgical resection is an important modality for the treatment of hepatocellular carcinoma (HCC), the impact of the operative method on…”
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Prospective Cohort Study of Transarterial Chemoembolization for Unresectable Hepatocellular Carcinoma in 8510 Patients
Published in Gastroenterology (New York, N.Y. 1943) (01-08-2006)“…Background & Aims: To elucidate the survival of the patients with unresectable hepatocellular carcinoma (HCC) who underwent transcatheter arterial lipiodol…”
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13
Report of the 18th follow-up survey of primary liver cancer in Japan
Published in Hepatology Research (01-11-2010)“…In the 18th Nationwide Follow‐Up Survey of Primary Liver Cancer in Japan, 20 753 people were newly registered as patients with primary liver cancer at 544…”
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Dominant Expression of DCLK1 in Human Pancreatic Cancer Stem Cells Accelerates Tumor Invasion and Metastasis
Published in PloS one (14-01-2016)“…Patients with pancreatic cancer typically develop tumor invasion and metastasis in the early stage. These malignant behaviors might be originated from cancer…”
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15
Hypervascular Hepatocellular Carcinoma: Correlation between Biologic Features and Signal Intensity on Gadoxetic Acid―enhanced MR Images
Published in Radiology (01-12-2012)“…To analyze the correlation among biologic features, tumor marker production, and signal intensity at gadoxetic acid-enhanced MR imaging in hepatocellular…”
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Gd‐EOB‐DTPA‐enhanced magnetic resonance imaging and alpha‐fetoprotein predict prognosis of early‐stage hepatocellular carcinoma
Published in Hepatology (Baltimore, Md.) (01-11-2014)“…The survival of patients with hepatocellular carcinoma (HCC) is often individually different even after surgery for early‐stage tumors. Gadolinium ethoxybenzyl…”
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FGF3/FGF4 amplification and multiple lung metastases in responders to sorafenib in hepatocellular carcinoma
Published in Hepatology (Baltimore, Md.) (01-04-2013)“…The response rate to sorafenib in hepatocellular carcinoma (HCC) is relatively low (0.7%‐3%), however, rapid and drastic tumor regression is occasionally…”
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Acquired Resistance with Epigenetic Alterations Under Long-Term Antiangiogenic Therapy for Hepatocellular Carcinoma
Published in Molecular cancer therapeutics (01-06-2017)“…Antiangiogenic therapy is initially effective for several solid tumors including hepatocellular carcinoma; however, they finally relapse and progress,…”
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Surgeons' involvement in COVID-19 treatment: a practice by a regional core hospital in Japan to avoid physician burnout
Published in BMC health services research (12-01-2023)“…To prevent task accumulation on certain divisions, our institution developed a unique system of allocating inpatient treatment of COVID-19 patients to doctors…”
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Anatomic resection reduces the recurrence of solitary hepatocellular carcinoma ≤5 cm without macrovascular invasion
Published in The American journal of surgery (01-06-2014)“…Abstract Background In patients with solitary hepatocellular carcinoma ≤5 cm without macrovascular invasion, it is unknown whether the initial anatomic…”
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