Search Results - "Arighi, Elena"

GDNF Promotes Tubulogenesis of GFRα1-Expressing MDCK Cells by Src-Mediated Phosphorylation of Met Receptor Tyrosine Kinase by Popsueva, Anna, Poteryaev, Dmitry, Arighi, Elena, Meng, Xiaojuan, Angers-Loustau, Alexandre, Kaplan, David, Saarma, Mart, Sariola, Hannu

“…Glial cell line-derived neurotrophic factor (GDNF) and hepatocyte growth factor (HGF) are multifunctional signaling molecules in embryogenesis. HGF binds to…”
Get full text

A Recombinant Mutant Vascular Endothelial Growth Factor-C that Has Lost Vascular Endothelial Growth Factor Receptor-2 Binding, Activation, and Vascular Permeability Activities by Joukov, V, Kumar, V, Sorsa, T, Arighi, E, Weich, H, Saksela, O, Alitalo, K

“…The vascular endothelial growth factor (VEGF) and the VEGF-C promote growth of blood vessels and lymphatic vessels, respectively. VEGF activates the…”
Get full text

Bmx Tyrosine Kinase Has a Redundant Function Downstream of Angiopoietin and Vascular Endothelial Growth Factor Receptors in Arterial Endothelium by Rajantie, Iiro, Ekman, Niklas, Iljin, Kristiina, Arighi, Elena, Gunji, Yuji, Kaukonen, Jaakko, Palotie, Aarno, Dewerchin, Mieke, Carmeliet, Peter, Alitalo, Kari

“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
Get full text

Loss of function effect of RET mutations causing Hirschsprung disease by Pasini, Barbara, Borrello, Maria Grazia, Greco, Angela, Bongarzone, Italia, Luo, Yin, Mondellini, Piera, Alberti, Luisella, Miranda, Claudia, Arighi, Elena, Bocciardi, Renata, Seri, Marco, Barone, Virginia, Radice, Maria Teresa, Romeo, Giovanni, Pierotti, Marco A

“…We have introduced three Hirschsprung (HSCR) mutations localized in the tyrosine kinase domain of RET into the RET/PTC2 chimaeric oncogene which is capable of…”
Get full text

Identification of Shc docking site on Ret tyrosine kinase by ARIGHI, E, ALBERTI, L, BORRELLO, M. G, TORRITI, F, GHIZZONI, S, RIZZETTI, M. G, PELICCI, G, PASINI, B, BONGARZONE, I, PIUTTI, C, PIEROTTI, M. A

“…The RET proto-oncogene encodes two isoforms of a receptor type tyrosine kinase which plays a role in neural crest and kidney development. Distinct germ-line…”
Get full text

The Bmx tyrosine kinase is activated by IL-3 and G-CSF in a PI-3K dependent manner by EKMAN, N, ARIGHI, E, RAJANTIE, I, SAHARINEN, P, RISTIMÄKI, A, SILVENNOINEN, O, ALITALO, K

“…Cytoplasmic protein tyrosine kinases play crucial roles in signaling via a variety of cell surface receptors. The Bmx tyrosine kinase, a member of the Tec…”
Get full text

RET tyrosine kinase signaling in development and cancer by Arighi, Elena, Borrello, Maria Grazia, Sariola, Hannu

“…The variety of diseases caused by mutations in RET receptor tyrosine kinase provides a classic example of phenotypic heterogeneity. Gain-of-function mutations…”
Get full text

Key role of Shc signaling in the transforming pathway triggered by Ret/ptc2 oncoprotein by MERCALLI, Elena, GHIZZONI, Simona, ARIGHI, Elena, ALBERTI, Luisella, SANGREGORIO, Romina, RADICE, Maria T, GISHIZKY, Mikhail L, PIEROTTI, Marco A, BORRELLO, Maria Grazia

“…The RET/PTC oncogenes, generated by chromosomal rearrangements in papillary thyroid carcinomas, are constitutively activated versions of protoRET, a gene…”
Get full text

Differential requirement of Tyr1062 multidocking site by RET isoforms to promote neural cell scattering and epithelial cell branching by DEGL'INNOCENTI, Debora, ARIGHI, Elena, POPSUEVA, Anna, SANGREGORIO, Romina, ALBERTI, Luisella, RIZZETTI, Maria Grazia, FERRARIO, Cristina, SARIOLA, Hannu, PIEROTTI, Marco A, BORRELLO, Maria Grazia

“…The receptor tyrosine kinase RET is alternatively spliced to yield two main isoforms, RET9 and RET51, which differ in their carboxyl terminal. Activated RET…”
Get full text

Biological Effects of the Dual Phenotypic Janus Mutation of ret Cosegregating with Both Multiple Endocrine Neoplasia Type 2 and Hirschsprung’s Disease by Arighi, Elena, Popsueva, Anna, Degl’Innocenti, Debora, Borrello, Maria Grazia, Carniti, Cristiana, Perälä, Nina M, Pierotti, Marco A, Sariola, Hannu

“…Gain-of-function mutations of ret receptor tyrosine kinase, the signaling receptor for glial cell line-derived neurotrophic factor, cause sporadic thyroid and…”
Get full text

Induction of TNF-sensitive cellular phenotype by c-Myc involves p53 and impaired NF-κB activation by Klefstrom, Juha, Arighi, Elena, Littlewood, Trevor, Jäättelä, Marja, Saksela, Eero, Evan, Gerard I., Alitalo, Kari

“…Normal fibroblasts are resistant to the cytotoxic action of tumor necrosis factor (TNF), but are rendered TNF‐sensitive upon deregulation of c‐Myc. To assess…”
Get full text

The Full Oncogenic Activity of Ret/ptc2 Depends on Tyrosine 539, a Docking Site for Phospholipase Cγ by Borrello, Maria Grazia, Alberti, Luisella, Arighi, Elena, Bongarzone, Italia, Battistini, Carlo, Bardelli, Alberto, Pasini, Barbara, Piutti, Claudia, Rizzetti, Maria Grazia, Mondellini, Piera, Radice, Maria Teresa, Pierotti, Marco A.

“…RET/PTC oncogenes, generated by chromosomal rearrangements in papillary thyroid carcinomas, are constitutively activated versions of proto-RET, a gene coding…”
Get full text

RET activation by germline MEN2A and MEN2B mutations by Borrello, M G, Smith, D P, Pasini, B, Bongarzone, I, Greco, A, Lorenzo, M J, Arighi, E, Miranda, C, Eng, C, Alberti, L

“…The RET proto-oncogene encodes a receptor tyrosine kinase (TK). It has been shown that distinct germline mutations in the RET proto-oncogene are associated…”
Get more information

Differential interaction of Enigma protein with the two RET isoforms by Borrello, Maria Grazia, Mercalli, Elena, Perego, Carla, Degl'Innocenti, Debora, Ghizzoni, Simona, Arighi, Elena, Eroini, Barbara, Rizzetti, Maria Grazia, Pierotti, Marco A

“…The receptor tyrosine kinase RET, with a known role in embryonic development and in human pathologies, is alternatively spliced to yield at least two…”
Get full text

GDNF promotes tubulogenesis of GFRalpha1-expressing MDCK cells by Src-mediated phosphorylation of Met receptor tyrosine kinase by Popsueva, Anna, Poteryaev, Dmitry, Arighi, Elena, Meng, Xiaojuan, Angers-Loustau, Alexandre, Kaplan, David, Saarma, Mart, Sariola, Hannu

“…Glial cell line-derived neurotrophic factor (GDNF) and hepatocyte growth factor (HGF) are multifunctional signaling molecules in embryogenesis. HGF binds to…”
Get full text

The oncogenic versions of the Ret and Trk tyrosine kinases bind Shc and Grb2 adaptor proteins by Borrello, M G, Pelicci, G, Arighi, E, De Filippis, L, Greco, A, Bongarzone, I, Rizzetti, M, Pelicci, P G, Pierotti, M A

“…Proto-TRK and proto-RET genes encode receptor type tyrosine kinases. Oncogenic rearrangements of both proto-oncogenes have been detected with a significant…”
Get more information

RET activation in medullary carcinomas by Pierotti, Marco A, Arighi, Elena, Degl'innocenti, Debora, Borrello, Maria Grazia

Get more information