Search Results - "Arif, J."

Platelet Inhibition With Ticagrelor 60 mg Versus 90 mg Twice Daily in the PEGASUS-TIMI 54 Trial by Storey, Robert F., MD, DM, Angiolillo, Dominick J., MD, Bonaca, Marc P., MD, MPH, Thomas, Mark R., MD, Judge, Heather M., PhD, Rollini, Fabiana, MD, Franchi, Francesco, MD, Ahsan, Arif J., MD, Bhatt, Deepak L., MD, MPH, Kuder, Julia F., MA, Steg, Philippe Gabriel, MD, Cohen, Marc, MD, Muthusamy, Rangasamy, MD, Braunwald, Eugene, MD, Sabatine, Marc S., MD, MPH

“…Abstract Background The PEGASUS-TIMI 54 (Prevention of Cardiovascular Events in Patients with Prior Heart Attack Using Ticagrelor Compared to Placebo on a…”
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How toxic is the COVID-19 drug azithromycin in the presence of Posidonia oceanica? Toxicokinetics and experimental approach of meiobenthic nematodes from a metallically pristine area by Badraoui, Riadh, Mannai, Ghofrane, Siddiqui, Arif J., Pacioglu, Octavian, Rudayni, Hassan A., Boufahja, Fehmi, Essid, Naceur

“…The current study presents the results of an experiment carried to assess the impact of azithromycin, a COVID-19 drug, probably accumulated in marine sediments…”
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Antioxidant and Anti-Inflammatory Effects of Zingiber officinale roscoe and Allium subhirsutum: In Silico, Biochemical and Histological Study by Zammel, Nourhene, Saeed, Mohd, Bouali, Nouha, Elkahoui, Salem, Alam, Jahoor M., Rebai, Tarek, Kausar, Mohd A., Adnan, Mohd, Siddiqui, Arif J., Badraoui, Riadh

“…In this study, the antioxidant and anti-inflammatory effects of Zingiber officinale roscoe and Allium subhirsutum aqueous extracts were examined in a…”
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Ecotoxicity of chrysene and phenanthrene on meiobenthic nematodes with a case study of Terschellingia longicaudata: Taxonomics, toxicokinetics, and molecular interactions modelling by Badraoui, Riadh, Allouche, Mohamed, El Ouaer, Dhia, Siddiqui, Arif J., Ishak, Sahar, Hedfi, Amor, Beyrem, Hamouda, Pacioglu, Octavian, Rudayni, Hassan A., Boufahja, Fehmi

“…Polycyclic aromatic hydrocarbons (PAHs) are toxic for humans and marine fauna alike. The current study assessed the impact of PAHs on the migratory behaviour…”
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Nanotechnology-Based Strategies for the Management of COVID-19: Recent Developments and Challenges by Singh, Ritu, Behera, Monalisha, Kumari, Nisha, Kumar, Sanjeev, Rajput, Vishnu D, Minkina, Tatiana M, Adnan, Mohd, Siddiqui, Arif J, Kumar, Narendra

“…COVID-19 is a respiratory disease caused by a newly identified coronavirus named severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Since its…”
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Expression Profiling of Selected Immune Genes and Trabecular Microarchitecture in Breast Cancer Skeletal Metastases Model: Effect of α–Tocopherol Acetate Supplementation by Badraoui, Riadh, Saeed, Mohd, Bouali, Nouha, Hamadou, Walid S., Elkahoui, Salem, Alam, Mohammad J., Siddiqui, Arif J., Adnan, Mohd, Saoudi, Mongi, Rebai, Tarek

“…Breast cancer bone metastases (BCBM) result in serious skeletal morbidity. Although there have been important advances in cancer treatment methods such as…”
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Antiviral Effects of Artemisinin and Its Derivatives against SARS-CoV-2 Main Protease: Computational Evidences and Interactions with ACE2 Allelic Variants by Badraoui, Riadh, Saoudi, Mongi, Hamadou, Walid S, Elkahoui, Salem, Siddiqui, Arif J, Alam, Jahoor M, Jamal, Arshad, Adnan, Mohd, Suliemen, Abdel M E, Alreshidi, Mousa M, Yadav, Dharmendra K, Naïli, Houcine, Ben-Nasr, Hmed

“…Fighting against the emergent coronavirus disease (COVID-19) remains a big challenge at the front of the world communities. Recent research has outlined the…”
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(−)-Epigallocatechin gallate (EGCG) pharmacokinetics and molecular interactions towards amelioration of hyperglycemia, hyperlipidemia associated hepatorenal oxidative injury in alloxan induced diabetic mice by Soussi, Ahlem, Gargouri, Manel, Magné, Christian, Ben-Nasr, Hmed, Kausar, Mohd Adnan, Siddiqui, Arif J., Saeed, Mohd, Snoussi, Mejdi, Adnan, Mohd, El-Feki, Abdelfattah, Chappard, Daniel, Badraoui, Riadh

“…Diabetes mellitus has become a serious problem associated with health complications, such as metabolism disorders and liver-kidney dysfunction. The…”
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Pharmacokinetics and Therapeutic Potential of Teucrium polium against Liver Damage Associated Hepatotoxicity and Oxidative Injury in Rats: Computational, Biochemical and Histological Studies by Rahmouni, Fatma, Badraoui, Riadh, Ben-Nasr, Hmed, Bardakci, Fevzi, Salem Elkahoui, Siddiqui, Arif J, Saeed, Mohd, Snoussi, Mejdi, Saoudi, Mongi, Rebai, Tarek

“…This study investigated the druggability, pharmacokinetics and ethyl acetate extract of Teucrium polium (EA T. polium) and the protective effect against carbon…”
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Chemical Composition, Nutritional Value, Antioxidative, and In Vivo Anti-inflammatory Activities of Opuntia Stricta Cladode by Harrabi, Bahira, Ben Nasr, Hmed, Amri, Zahra, Brahmi, Faten, El Feki, Abdelfattah, Zeghal, Khaled, Ghozzi, Hanéne, Siddiqui, Arif J., Adnan, Mohd, Aloufi, Bandar, Jilani, Saoussen, Boufahja, Fehmi, Badraoui, Riadh

“…The cactus family plant has been used in folk medicine for a long time. In this work, Opuntia stricta chemical composition and its antioxidative and…”
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Fifteen Years of Sm-p80-Based Vaccine Trials in Nonhuman Primates: Antibodies From Vaccinated Baboons Confer Protection in vivo and in vitro From Schistosoma mansoni and Identification of Putative Correlative Markers of Protection by Zhang, Weidong, Le, Loc, Ahmad, Gul, Molehin, Adebayo J, Siddiqui, Arif J, Torben, Workineh, Karmakar, Souvik, Rojo, Juan U, Sennoune, Souad, Lazarus, Samara, Khatoon, Sabiha, Freeborn, Jasmin, Sudduth, Justin, Rezk, Ashraf F, Carey, David, Wolf, Roman F, Papin, James F, Damian, Ray, Gray, Sean A, Marks, Florian, Carter, Darrick, Siddiqui, Afzal A

“…Recent advances in systems biology have shifted vaccine development from a largely trial-and-error approach to an approach that promote rational design through…”
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Sm‐p80‐based schistosomiasis vaccine: double‐blind preclinical trial in baboons demonstrates comprehensive prophylactic and parasite transmission‐blocking efficacy by Zhang, Weidong, Molehin, Adebayo J., Rojo, Juan U., Sudduth, Justin, Ganapathy, Pramodh K., Kim, Eunjee, Siddiqui, Arif J., Freeborn, Jasmin, Sennoune, Souad R., May, Jordan, Lazarus, Samra, Nguyen, Catherine, Redman, Whitni K., Ahmad, Gul, Torben, Workineh, Karmakar, Souvik, Le, Loc, Kottapalli, Kameswara R., Kottapalli, Pratibha, Wolf, Roman F., Papin, James F., Carey, David, Gray, Sean A., Bergthold, Jenn D., Damian, Raymond T., Mayer, Bryan T., Marks, Florian, Reed, Steven G., Carter, Darrick, Siddiqui, Afzal A.

“…Schistosomiasis is of public health importance to an estimated one billion people in 79 countries. A vaccine is urgently needed. Here, we report the results of…”
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Chitosan-Based Gastric Dressing Materials Loaded with Pomegranate Peel as Bioactive Agents: Pharmacokinetics and Effects on Experimentally Induced Gastric Ulcers in Rabbits by Jebahi, Samira, Ben Salah, Ghada, Jarray, Soufien, Naffati, Mounir, Ahmad, Mohammad Ayaz, Brahmi, Faten, Saeed, Mohd, Siddiqui, Arif J, Abdelmajid, Khabir, Badraoui, Riadh

“…This study reported the fabrication and characterization of gastric dressing, composed of gelatine (GEL), chitosan (CH), and pomegranate peel (PP) extract. The…”
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Sm‐p80‐based vaccine trial in baboons: efficacy when mimicking natural conditions of chronic disease, praziquantel therapy, immunization, and Schistosoma mansoni re‐encounter by Siddiqui, Arif J., Molehin, Adebayo J., Zhang, Weidong, Ganapathy, Pramodh K., Kim, Eunjee, Rojo, Juan U., Redman, Whitni K., Sennoune, Souad R., Sudduth, Justin, Freeborn, Jasmin, Hunter, Derick, Kottapalli, Kameswara R., Kottapalli, Pratibha, Wettashinghe, Ruwanthi, Dam, Govert J., Corstjens, Paul L.A.M., Papin, James F., Carey, David, Torben, Workineh, Ahmad, Gul, Siddiqui, Afzal A.

“…Sm‐p80‐based vaccine efficacy for Schistosoma mansoni was evaluated in a baboon model of infection and disease. The study was designed to replicate a human…”
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Elucidation of Cellular Responses in Non-human Primates With Chronic Schistosomiasis Followed by Praziquantel Treatment by Melkus, Michael W, Le, Loc, Siddiqui, Arif J, Molehin, Adebayo J, Zhang, Weidong, Lazarus, Samra, Siddiqui, Afzal A

“…For decades, mass drug treatment with praziquantel (PZQ) has been utilized to treat schistosomiasis, yet reinfection and the risk of drug resistance are among…”
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Phytochemical Analysis, Antioxidant, and Antimicrobial Activities of Ducrosia flabellifolia: A Combined Experimental and Computational Approaches by Snoussi, Mejdi, Ahmad, Iqrar, Aljohani, Abdullah M. A., Patel, Harun, Abdulhakeem, Mohammad A., Alhazmi, Yasser S., Tepe, Bektas, Adnan, Mohd, Siddiqui, Arif J., Sarikurkcu, Cengiz, Riadh, Badraoui, De Feo, Vincenzo, Alreshidi, Mousa, Noumi, Emira

“…Ducrosia flabellifolia Boiss. is a rare desert plant known to be a promising source of bioactive compounds. In this paper, we report for the first time the…”
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Schistosoma mansoni antigen Sm-p80: prophylactic efficacy using TLR4 agonist vaccine adjuvant glucopyranosyl lipid A-Alum in murine and non-human primate models by Zhang, Weidong, Ahmad, Gul, Molehin, Adebayo J, Torben, Workineh, Le, Loc, Kim, Eunjee, Lazarus, Samra, Siddiqui, Arif J, Carter, Darrick, Siddiqui, Afzal A

“…Sm-p80, the large subunit of Schistosoma mansoni calpain, is a leading candidate for a schistosomiasis vaccine. The prophylactic and antifecundity efficacy of…”
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Cross-species prophylactic efficacy of Sm-p80-based vaccine and intracellular localization of Sm-p80/Sm-p80 ortholog proteins during development in Schistosoma mansoni, Schistosoma japonicum, and Schistosoma haematobium by Molehin, Adebayo J., Sennoune, Souad R., Zhang, Weidong, Rojo, Juan U., Siddiqui, Arif J., Herrera, Karlie A., Johnson, Laura, Sudduth, Justin, May, Jordan, Siddiqui, Afzal A.

“…Schistosomiasis remains a major global health problem. Despite large-scale schistosomiasis control efforts, clear limitations such as possible emergence of…”
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Consistent platelet inhibition with ticagrelor 60 mg twice-daily following myocardial infarction regardless of diabetes status by Thomas, Mark R, Angiolillo, Dominick J, Bonaca, Marc P, Ajjan, Ramzi A, Judge, Heather M, Rollini, Fabiana, Franchi, Francesco, Ahsan, Arif J, Bhatt, Deepak L, Kuder, Julia F, Steg, Philippe Gabriel, Cohen, Marc, Muthusamy, Rangasamy, Sabatine, Marc S, Storey, Robert F

“…Diabetes increases cardiovascular risk and reduces pharmacodynamic response to some oral antiplatelet drugs. This study aimed to determine whether ticagrelor…”
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Synthesis of primaquine glyco‐conjugates as potential tissue schizontocidal antimalarial agents by Azad, Chandra S., Saxena, Mridula, Siddiqui, Arif J., Bhardwaj, Jyoti, Puri, Sunil K., Dutta, Guru P., Anand, Nitya, Saxena, Anil K.

“…Primaquine (PQ) is the only drug used to prevent relapse of malaria due to P. vivax and P. ovale, by eradicating the dormant liver form of the parasite…”
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