Search Results - "Arienti, Flavio"

Alternative Activation of Human Plasmacytoid DCs In Vitro and in Melanoma Lesions: Involvement of LAG-3 by Camisaschi, Chiara, De Filippo, Annamaria, Beretta, Valeria, Vergani, Barbara, Villa, Antonello, Vergani, Elisabetta, Santinami, Mario, Cabras, Antonello Domenico, Arienti, Flavio, Triebel, Frédéric, Rodolfo, Monica, Rivoltini, Licia, Castelli, Chiara

“…Plasmacytoid dendritic cells (pDCs) at tumor sites are often tolerogenic. Although pDCs initiate innate and adaptive immunity upon Toll-like receptor (TLR)…”
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Cancer-associated foam cells hamper protective T cell immunity and favor tumor progression in human colon carcinogenesis by Daveri, Elena, Vergani, Barbara, Lalli, Luca, Ferrero, Giulio, Casiraghi, Elena, Cova, Agata, Zorza, Marta, Huber, Veronica, Gariboldi, Manuela, Pasanisi, Patrizia, Guarrera, Simonetta, Morelli, Daniele, Arienti, Flavio, Vitellaro, Marco, Corsetto, Paola A, Rizzo, Angela M, Stroscia, Martina, Frati, Paola, Lagano, Vincenzo, Cattaneo, Laura, Sabella, Giovanna, Leone, Biagio E, Milione, Massimo, Sorrentino, Luca, Rivoltini, Licia

“…Colorectal cancer (CRC) remains a significant healthcare burden worldwide, characterized by a complex interplay between obesity and chronic inflammation. While…”
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Back to simplicity: a four-marker blood cell score to quantify prognostically relevant myeloid cells in melanoma patients by Huber, Veronica, Di Guardo, Lorenza, Lalli, Luca, Giardiello, Daniele, Cova, Agata, Squarcina, Paola, Frati, Paola, Di Giacomo, Anna Maria, Pilla, Lorenzo, Tazzari, Marcella, Camisaschi, Chiara, Arienti, Flavio, Castelli, Chiara, Rodolfo, Monica, Beretta, Valeria, Di Nicola, Massimo, Maio, Michele, Del Vecchio, Michele, de Braud, Filippo, Mariani, Luigi, Rivoltini, Licia

“…BackgroundMyeloid-derived suppressor cells (MDSC), a cornerstone of cancer-related immunosuppression, influence response to therapy and disease outcomes in…”
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Detection of mutated BRAFV600E variant in circulating DNA of stage III–IV melanoma patients by Daniotti, Maria, Vallacchi, Viviana, Rivoltini, Licia, Patuzzo, Roberto, Santinami, Mario, Arienti, Flavio, Cutolo, Gianluca, Pierotti, Marco A., Parmiani, Giorgio, Rodolfo, Monica

“…BRAFV600E is the most represented somatic point mutation in cutaneous melanoma, thus providing a unique molecular marker for this disease. The development of…”
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Impaired STAT Phosphorylation in T Cells from Melanoma Patients in Response to IL-2: Association with Clinical Stage by Mortarini, Roberta, Vegetti, Claudia, Molla, Alessandra, Arienti, Flavio, Ravagnani, Fernando, Maurichi, Andrea, Patuzzo, Roberto, Santinami, Mario, Anichini, Andrea

“…Purpose: To assess the extent of signal transducer and activator of transcription (STAT) activation in response to interleukin 2 (IL-2) in melanoma patients' T…”
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Induction of Both CD8+ and CD4+ T-Cell–Mediated Responses in Colorectal Cancer Patients by Colon Antigen-1 by MACCALLI, Cristina, DI CRISTANZIANO, Veronica, PERRONE, Maria P, CASTELLI, Chiara, RIVOLTINI, Licia, ZAGONEL, Vittorina, TARTAGLIA, Marco, PARMIANI, Giorgio, BELARDELLI, Filippo, FODALE, Valentina, CORSI, Domenico, D'AGOSTINO, Giuseppina, PETRANGELI, Valentina, LAURENTI, Luca, GUIDA, Sofia, MAZZOCCHI, Arabella, ARIENTI, Flavio

“…Purpose: Colon antigen-1 (COA-1) was recently identified as a novel antigen of colorectal cancer encoded by the UBXD5 gene. Here, we evaluated whether a…”
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Identification of the novel HLA‐C allele, HLA‐C04:520 by Zucchini, Monica, Billiani, Camilla, Mazzocchi, Arabella, Arienti, Flavio, Taverna, Francesca

“…HLA‐C*04:520, a novel HLA‐C allele, differs from HLA‐C*04:01:01 by one mismatch in exon 5…”
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Tumor-derived microRNAs induce myeloid suppressor cells and predict immunotherapy resistance in melanoma by Huber, Veronica, Vallacchi, Viviana, Fleming, Viktor, Hu, Xiaoying, Cova, Agata, Dugo, Matteo, Shahaj, Eriomina, Sulsenti, Roberta, Vergani, Elisabetta, Filipazzi, Paola, De Laurentiis, Angela, Lalli, Luca, Di Guardo, Lorenza, Patuzzo, Roberto, Vergani, Barbara, Casiraghi, Elena, Cossa, Mara, Gualeni, Ambra, Bollati, Valentina, Arienti, Flavio, De Braud, Filippo, Mariani, Luigi, Villa, Antonello, Altevogt, Peter, Umansky, Viktor, Rodolfo, Monica, Rivoltini, Licia

“…The accrual of myeloid-derived suppressor cells (MDSCs) represents a major obstacle to effective immunotherapy in cancer patients, but the mechanisms…”
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Shear-Induced Encapsulation into Red Blood Cells: A New Microfluidic Approach to Drug Delivery by Piergiovanni, Monica, Casagrande, Giustina, Taverna, Francesca, Corridori, Ilaria, Frigerio, Marta, Bianchi, Elena, Arienti, Flavio, Mazzocchi, Arabella, Dubini, Gabriele, Costantino, Maria Laura

“…Encapsulating molecules into red blood cells (RBCs) is a challenging topic for drug delivery in clinical practice, allowing to prolong the residence time in…”
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A Microsatellite in the Coding Sequence of HLA-A/B Is a Mutation Hotspot in Colon Cancer With Microsatellite Instability by Raab, William J., Mazzocchi, Arabella, Radice, Paolo, Sahoo, Debashis, Castelli, Chiara, Dalerba, Piero, Behroozikhah, Mahdi, Lombardo, Claudia, Novellino, Luisa, Cifola, Ingrid, Casati, Chiara, Longa, Elena Dalla, Schweighoffer, Tamás, Arienti, Flavio, Parmiani, Giorgio

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113 Longitudinal assessment of plasma EBV-DNA in non-endemic EBV-related nasopharyngeal cancers (NPC) by Alfieri, Salvatore, Marceglia, Sara, Sciortino, Carolina, Bravo, Walter Ferrari, Piscitelli, Maria Luigia, Zucchini, Monica, Nuzzolese, Imperia, Romanò, Rebecca, Cavalieri, Stefano, Bergamini, Cristiana, Colombo, Elena, Carlo, Resteghini, Ottini, Arianna, Calareso, Giuseppina, Quattrone, Pasquale, Loris, De Cecco, Orlandi, Ester, Franceschini, Marzia, Iacovelli, Nicola Alessandro, Deganello, Alberto, Bossi, Paolo, Locati, Laura Deborah, Arienti, Flavio, Taverna, Francesca, Licitra, Lisa Francesca

“…Plasma Epstein Barr virus (EBV)-DNA is employed as a biomarker for EBER (EBV-encoded RNA) positive nasopharyngeal cancer (NPC) patients. In Europe, the use of…”
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Overcoming melanoma resistance to vemurafenib by targeting CCL2-induced miR-34a, miR-100 and miR-125b by Vergani, Elisabetta, Di Guardo, Lorenza, Dugo, Matteo, Rigoletto, Sara, Tragni, Gabrina, Ruggeri, Roberta, Perrone, Federica, Tamborini, Elena, Gloghini, Annunziata, Arienti, Flavio, Vergani, Barbara, Deho, Paola, De Cecco, Loris, Vallacchi, Viviana, Frati, Paola, Shahaj, Eriomina, Villa, Antonello, Santinami, Mario, De Braud, Filippo, Rivoltini, Licia, Rodolfo, Monica

“…In melanoma, the adaptative cell response to BRAF inhibitors includes altered patterns of cytokine production contributing to tumor progression and drug…”
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The Real Life Accessibility to CAR T-Cell Therapy: Current Experience in the Only Active Center in Italy by Guidetti, Anna, Perrone, Giulia, Coluccia, Paola, Fumagalli, Luca, Dodero, Anna, Farina, Lucia, Arienti, Flavio, Bagnoli, Filippo, Pappalettera, Luca, Degli Innocenti, Debora, Carniti, Cristiana, Codazzi, Daniela, Corradini, Paolo

“…BACKGROUND. Axicabtagene ciloleucel and tisagenlecleucel have been approved by FDA and EMA for the treatment of relapsed/refractory diffuse large B-cell and…”
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A Supportive Care in Cancer Unit Reduces Costs and Hospitalizations for Transfusions in a Comprehensive Cancer Center by Ripamonti, Carla Ida, Molani, Pietro, Desti, Cinzia, Boscagli, Giacomo, Ravagnani, Fernando, Arienti, Flavio, Di Cristo, Clementina

“…Purpose Among patients with solid or hematologic malignancies undergoing oncologic therapies, blood product transfusions (BPT) are a relevant reason for…”
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Preclinical pharmacology of patient-derived extracellular vesicles for the intraoperative imaging of tumors by Villa, Alessandro, Crescenti, Daniela, De Mitri, Zemira, Crippa, Elisabetta, Rosa, Silvia, Rizzi, Nicoletta, Shojaei-Ghahrizjani, Fereshteh, Rebecchi, Monica, Vincenti, Simona, Selmin, Francesca, Brunialti, Electra, Simonotti, Nicolò, Maspero, Marianna, Dei Cas, Michele, Recordati, Camilla, Paltrinieri, Saverio, Giordano, Alessia, Paroni, Rita, Galassi, Margherita, Ladisa, Vito, Arienti, Flavio, Cilurzo, Francesco, Mazzaferro, Vincenzo, Ciana, Paolo

“…Extracellular vesicles (EVs) derived from the plasma of oncological patients exhibit significant tumor-targeting properties, unlike those from healthy…”
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Adaptive Immunity in Fibrosarcomatous Dermatofibrosarcoma Protuberans and Response to Imatinib Treatment by Tazzari, Marcella, Indio, Valentina, Vergani, Barbara, De Cecco, Loris, Rini, Francesca, Negri, Tiziana, Camisaschi, Chiara, Fiore, Marco, Stacchiotti, Silvia, Dagrada, G. Paolo, Casali, Paolo G., Gronchi, Alessandro, Astolfi, Annalisa, Pantaleo, Maria A., Villa, Antonello, Lombardo, Claudia, Arienti, Flavio, Pilotti, Silvana, Rivoltini, Licia, Castelli, Chiara

“…Dermatofibrosarcoma protuberans (DFSP), although rare, is the most frequent skin sarcoma. Here, we focus on DFSP carrying the fibrosarcomatous transformation…”
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Application of Controlled Shear Stresses on the Erythrocyte Membrane as a New Approach to Promote Molecule Encapsulation by Casagrande, Giustina, Arienti, Flavio, Mazzocchi, Arabella, Taverna, Francesca, Ravagnani, Fernando, Costantino, MariaLaura

“…Human red blood cells (RBCs) have a remarkable capacity to undergo reversible membrane swelling. Resealed erythrocytes have been proposed as carriers and…”
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Monocytes in leukapheresis products affect the outcome of CD19–targeted CAR T-cell therapy in patients with lymphoma by Carniti, Cristiana, Caldarelli, Nicole M., Agnelli, Luca, Torelli, Tommaso, Ljevar, Silva, Jonnalagadda, Sadhana, Zanirato, Giada, Fardella, Eugenio, Stella, Federico, Lorenzini, Daniele, Brich, Silvia, Arienti, Flavio, Dodero, Anna, Chiappella, Annalisa, Magni, Martina, Corradini, Paolo

“…•Combining circulating absolute monocyte count and a 4-gene monocyte signature at leukapheresis predicts PFS of LBCL receiving CAR T cells.•Monocytes depletion…”
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Epidural analgesia for cytoreductive surgery with peritonectomy and heated intraperitoneal chemotherapy by Piccioni, Federico, Casiraghi, Claudia, Fumagalli, Luca, Kusamura, Shigeki, Baratti, Dario, Deraco, Marcello, Arienti, Flavio, Langer, Martin

“…Abstract Purpose To evaluate epidural analgesia role after cytoreductive surgery with peritonectomy combined with heated intraperitoneal chemotherapy. Methods…”
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Tumor-Reactive CD8+ Early Effector T Cells Identified at Tumor Site in Primary and Metastatic Melanoma by ANICHINI, Andrea, MOLLA, Alessandra, PIRCHER, Hanspeter, DI NICOLA, Massimo, MORTARINI, Roberta, VEGETTI, Claudia, BERSANI, Ilaria, ZAPPASODI, Roberta, ARIENTI, Flavio, RAVAGNANI, Fernando, MAURICHI, Andrea, PATUZZO, Roberto, SANTINAMI, Mario

“…CD8(+) T cells at the earliest stage of effector generation have not been identified at tumor site of melanoma patients. Such early effectors, if present,…”
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