Search Results - "Arias de la Rosa, Iván"
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Preclinical Characterization of Pharmacologic NAD + Boosting as a Promising Therapeutic Approach in Rheumatoid Arthritis
Published in Arthritis & rheumatology (Hoboken, N.J.) (01-10-2023)“…We analyzed NAD metabolism in patients with rheumatoid arthritis (RA), its association with disease activity and clinical outcomes of RA, and the therapeutic…”
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Subclinical cardiovascular risk signs in adults with juvenile idiopathic arthritis in sustained remission
Published in Pediatric rheumatology online journal (14-07-2020)“…Background Juvenile Idiopathic Arthritis (JIA) is one of the most common chronic diseases of childhood that often persists into adulthood and can result in…”
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Complement component 3 as biomarker of disease activity and cardiometabolic risk factor in rheumatoid arthritis and spondyloarthritis
Published in Therapeutic advances in chronic disease (2020)“…Objective: To analyze the relationship between complement component 3 (C3) and the prevalence of cardiometabolic risk factors and disease activity in the…”
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Assessment of the relationship between estimated cardiovascular risk and structural damage in patients with axial spondyloarthritis
Published in Therapeutic advances in musculoskeletal disease (2020)“…Aims: To evaluate the association of estimated cardiovascular (CV) risk and subclinical atherosclerosis with radiographic structural damage in patients with…”
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Anti-dsDNA Antibodies Increase the Cardiovascular Risk in Systemic Lupus Erythematosus Promoting a Distinctive Immune and Vascular Activation
Published in Arteriosclerosis, thrombosis, and vascular biology (01-09-2021)“…ObjectiveSystemic lupus erythematosus (SLE) is associated to boosted atherosclerosis development and a higher cardiovascular disease risk. This study aimed to…”
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Nonalcoholic fatty liver disease in inflammatory arthritis: Relationship with cardiovascular risk
Published in Frontiers in immunology (23-09-2022)“…Liver disease is one of the most important causes of morbidity and mortality worldwide whose prevalence is dramatically increasing. The first sign of hepatic…”
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Circulating microRNAs as biomarkers of disease and typification of the atherothrombotic status in antiphospholipid syndrome
Published in Haematologica (Roma) (01-05-2018)“…We aimed to identify the plasma miRNA profile of antiphospholipid syndrome (APS) patients and to investigate the potential role of specific circulating miRNAs…”
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Early restoration of immune and vascular phenotypes in systemic lupus erythematosus and rheumatoid arthritis patients after B cell depletion
Published in Journal of cellular and molecular medicine (01-09-2019)“…This translational multi‐centre study explored early changes in serologic variables following B lymphocyte depletion by rituximab (RTX) treatment in systemic…”
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Pathogenic mechanisms involving the interplay between adipose tissue and auto-antibodies in rheumatoid arthritis
Published in iScience (16-09-2022)“…We aimed to evaluate the association between adipose tissue (AT) dysfunction, autoimmunity, and disease activity in rheumatoid arthritis (RA). A…”
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Cardiovascular risk factors in psoriatic disease: psoriasis versus psoriatic arthritis
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Ubiquinol Effects on Antiphospholipid Syndrome Prothrombotic Profile: A Randomized, Placebo-Controlled Trial
Published in Arteriosclerosis, thrombosis, and vascular biology (01-10-2017)“…OBJECTIVE—Antiphospholipid syndrome (APS) leukocytes exhibit an oxidative perturbation, directly linked to alterations in mitochondrial dynamics and…”
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Characterization of Antiphospholipid Syndrome Atherothrombotic Risk by Unsupervised Integrated Transcriptomic Analyses
Published in Arteriosclerosis, thrombosis, and vascular biology (01-02-2021)“…Our aim was to characterize distinctive clinical antiphospholipid syndrome phenotypes and identify novel microRNA (miRNA)-mRNA-intracellular signaling…”
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Axial and peripheral spondyloarthritis: does psoriasis influence the clinical expression and disease burden? Data from REGISPONSER registry
Published in Rheumatology (Oxford, England) (02-03-2021)“…Abstract Objective To evaluate whether the presence of psoriasis influences the clinical expression, disease activity and disease burden in both axial and…”
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Clinical and molecular insights into cardiovascular disease in psoriatic patients and the potential protective role of apremilast
Published in Frontiers in immunology (07-08-2024)“…Psoriatic disease, encompassing both psoriasis (Pso) and psoriatic arthritis (PsA), is closely intertwined with a significantly elevated risk of developing…”
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Splicing machinery is impaired in rheumatoid arthritis, associated with disease activity and modulated by anti-TNF therapy
Published in Annals of the rheumatic diseases (01-01-2022)“…To characterise splicing machinery (SM) alterations in leucocytes of patients with rheumatoid arthritis (RA), and to assess its influence on their clinical…”
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Impaired microRNA processing in neutrophils from rheumatoid arthritis patients confers their pathogenic profile. Modulation by biological therapies
Published in Haematologica (Roma) (01-09-2020)“…The aim of this study was to investigate the microRNA expression pattern in neutrophils from rheumatoid arthritis patients and its contribution to their…”
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Characterization of the inflammatory proteome of synovial fluid from patients with psoriatic arthritis: Potential treatment targets
Published in Frontiers in immunology (22-03-2023)“…1) To characterize the inflammatory proteome of synovial fluid (SF) from patients with Psoriatic Arthritis (PsA) using a high-quality throughput proteomic…”
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Exploring candidate biomarkers for rheumatoid arthritis through cardiovascular and cardiometabolic serum proteome profiling
Published in Frontiers in immunology (14-02-2024)“…RA patients are at higher risk of cardiovascular disease, influenced by therapies. Studying their cardiovascular and cardiometabolic proteome can unveil…”
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Molecular Characterization of Monocyte Subsets Reveals Specific and Distinctive Molecular Signatures Associated With Cardiovascular Disease in Rheumatoid Arthritis
Published in Frontiers in immunology (21-05-2019)“…This study, developed within the Innovative Medicines Initiative Joint Undertaking project PRECISESADS framework, aimed at functionally characterize the…”
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Molecular Changes in the Adipose Tissue Induced by Rheumatoid Arthritis: Effects of Disease-Modifying Anti-Rheumatic Drugs
Published in Frontiers in immunology (13-10-2021)“…Disease severity, progression and response to therapy might be worse in obese rheumatoid arthritis (RA) patients, but paradoxically, obesity also might protect…”
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