Search Results - "Arias, Simone C. A."
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Chronic VEGF blockade worsens glomerular injury in the remnant kidney model
Published in PloS one (22-06-2012)“…VEGF inhibition can promote renal vascular and parenchymal injury, causing proteinuria, hypertension and thrombotic microangiopathy. The mechanisms underlying…”
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Innate And Adaptive Immunity are Progressively Activated in Parallel with Renal Injury in the 5/6 Renal Ablation Model
Published in Scientific reports (09-06-2017)“…The mechanisms triggering renal inflammation in chronic kidney disease (CKD) are unclear. We performed a detailed analysis of the time course of innate and…”
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Journal Article -
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Pathogenic role of angiotensin II and the NF-κB system in a model of malignant hypertensive nephrosclerosis
Published in Hypertension research (01-06-2019)“…We previously reported that rats treated with an NF-κB inhibitor, pyrrolidine dithiocarbamate (PDTC), during lactation developed hypertension in adult life,…”
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A Novel Aldosterone Antagonist Limits Renal Injury in 5/6 Nephrectomy
Published in Scientific reports (11-08-2017)“…Aldosterone antagonists slow the progression of chronic kidney disease (CKD), but their use is limited by hyperkalemia, especially when associated with RAS…”
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Journal Article