Search Results - "Argov, Chanan M"

The DifferentialNet database of differential protein-protein interactions in human tissues by Basha, Omer, Shpringer, Rotem, Argov, Chanan M, Yeger-Lotem, Esti

“…Abstract DifferentialNet is a novel database that provides users with differential interactome analysis of human tissues (http://netbio.bgu.ac.il/diffnet/)…”
Get full text

Tissue-aware interpretation of genetic variants advances the etiology of rare diseases by Argov, Chanan M, Shneyour, Ariel, Jubran, Juman, Sabag, Eric, Mansbach, Avigdor, Sepunaru, Yair, Filtzer, Emmi, Gruber, Gil, Volozhinsky, Miri, Yogev, Yuval, Birk, Ohad, Chalifa-Caspi, Vered, Rokach, Lior, Yeger-Lotem, Esti

“…Pathogenic variants underlying Mendelian diseases often disrupt the normal physiology of a few tissues and organs. However, variant effect prediction tools…”
Get full text

Predicting molecular mechanisms of hereditary diseases by using their tissue‐selective manifestation by Simonovsky, Eyal, Sharon, Moran, Ziv, Maya, Mauer, Omry, Hekselman, Idan, Jubran, Juman, Vinogradov, Ekaterina, Argov, Chanan M, Basha, Omer, Kerber, Lior, Yogev, Yuval, Segrè, Ayellet V, Im, Hae Kyung, Birk, Ohad, Rokach, Lior, Yeger‐Lotem, Esti

“…How do aberrations in widely expressed genes lead to tissue‐selective hereditary diseases? Previous attempts to answer this question were limited to testing a…”
Get full text

ProAct: quantifying the differential activity of biological processes in tissues, cells, and user-defined contexts by Sharon, Moran, Gruber, Gil, Argov, Chanan M, Volozhinsky, Miri, Yeger-Lotem, Esti

“…Abstract The distinct functions and phenotypes of human tissues and cells derive from the activity of biological processes that varies in a context-dependent…”
Get full text

The differential activity of biological processes in tissues and cell subsets can illuminate disease-related processes and cell-type identities by Sharon, Moran, Vinogradov, Ekaterina, Argov, Chanan M, Lazarescu, Or, Zoabi, Yazeed, Hekselman, Idan, Yeger-Lotem, Esti

“…Abstract Motivation The distinct functionalities of human tissues and cell types underlie complex phenotype–genotype relationships, yet often remain elusive…”
Get full text

Differential network analysis of multiple human tissue interactomes highlights tissue-selective processes and genetic disorder genes by Basha, Omer, Argov, Chanan M, Artzy, Raviv, Zoabi, Yazeed, Hekselman, Idan, Alfandari, Liad, Chalifa-Caspi, Vered, Yeger-Lotem, Esti

“…Abstract Motivation Differential network analysis, designed to highlight network changes between conditions, is an important paradigm in network biology…”
Get full text