Search Results - "Argiro, Laurent"
-
1
Hox -dependent coordination of mouse cardiac progenitor cell patterning and differentiation
Published in eLife (17-08-2020)“…Perturbation of addition of second heart field (SHF) cardiac progenitor cells to the poles of the heart tube results in congenital heart defects (CHD). The…”
Get full text
Journal Article -
2
IL‐22 and IL‐22 binding protein (IL‐22BP) regulate fibrosis and cirrhosis in hepatitis C virus and schistosome infections
Published in Hepatology (Baltimore, Md.) (01-04-2015)“…Interleukin (IL)‐22 acts on epithelia, hepatocytes, and pancreatic cells and stimulates innate immunity, tissue protection, and repair. IL‐22 may also cause…”
Get full text
Journal Article -
3
Exome Sequencing Identifies Two Variants of the Alkylglycerol Monooxygenase Gene as a Cause of Relapses in Visceral Leishmaniasis in Children, in Sudan
Published in The Journal of infectious diseases (01-07-2017)“…Background. Visceral leishmaniasis (kala-azar, KA) is the most severe form of leishmaniasis, characterized by fever, weight loss, hepatosplenomegaly, and…”
Get full text
Journal Article -
4
IL2RA genetic variants reduce IL-2-dependent responses and aggravate human cutaneous leishmaniasis
Published in The Journal of immunology (1950) (15-03-2015)“…The outcome of Leishmania infections varies substantially, depending on the host and the parasite strain; infection may be asymptomatic or cause mild or severe…”
Get full text
Journal Article -
5
Potential Use of Interleukin-10 Blockade as a Therapeutic Strategy in Human Cutaneous Leishmaniasis
Published in Journal of immunology research (01-01-2015)“…Interleukin-10 overproduction has been associated with worse prognosis in human cutaneous leishmaniasis, while IFN-γ-dependent responses are associated with…”
Get full text
Journal Article -
6
Association Between a CTGF Gene Polymorphism and Systemic Sclerosis in a French Population
Published in Journal of rheumatology (01-02-2010)“…Objective. Systemic sclerosis (SSc) is a life-threatening autoimmune disease characterized by chronic fibrosis of the skin and internal organs. Connective…”
Get full text
Journal Article -
7
IL-17 and IL-22 are associated with protection against human kala azar caused by Leishmania donovani
Published in The Journal of clinical investigation (01-08-2009)“…IL-17 and IL-22 have been shown to increase protection against certain bacteria and fungal pathogens in experimental models. However, no human studies have…”
Get full text
Journal Article -
8
-
9
Genome-Wide Association Study Identifies Variants Associated With Progression of Liver Fibrosis From HCV Infection
Published in Gastroenterology (New York, N.Y. 1943) (01-11-2012)“…Background & Aims Polymorphisms in IL28B were shown to affect clearance of hepatitis C virus (HCV) infection in genome-wide association (GWA) studies. Only a…”
Get full text
Journal Article -
10
Th1/Th2 immune responses are associated with active cutaneous leishmaniasis and clinical cure is associated with strong interferon-γ production
Published in Human immunology (01-06-2009)“…Abstract In leishmaniasis, Th1-related cytokines production seems to be crucial for host control of parasite burden and clinical cure. Visceral and diffuse…”
Get full text
Journal Article -
11
-
12
Immunological and Genetic Evidence for a Crucial Role of IL-10 in Cutaneous Lesions in Humans Infected with Leishmania braziliensis
Published in The Journal of immunology (1950) (01-05-2008)“…In populations exposed to Leishmania braziliensis, certain subjects develop skin ulcers, whereas others are naturally protected against cutaneous…”
Get full text
Journal Article -
13
The IL17F and IL17RA Genetic Variants Increase Risk of Cerebral Malaria in Two African Populations
Published in Infection and immunity (01-02-2016)“…Cerebral malaria (CM) is a neurological complication of infection with Plasmodium falciparum that is partly caused by cytokine-mediated inflammation. It is not…”
Get full text
Journal Article -
14
A Functional IL22 Polymorphism (rs2227473) Is Associated with Predisposition to Childhood Cerebral Malaria
Published in Scientific reports (31-01-2017)“…Cerebral malaria (CM) is a severe complication of Plasmodium falciparum infection. This encephalopathy is characterized by coma and is thought to result from…”
Get full text
Journal Article -
15
Low plasma haptoglobin is a risk factor for life-threatening childhood severe malarial anemia and not an exclusive consequence of hemolysis
Published in Scientific reports (03-12-2018)“…Severe Malarial Anemia (SMA), a life-threatening childhood Plasmodium falciparum malaria syndrome requiring urgent blood transfusion, exhibits inflammatory and…”
Get full text
Journal Article -
16
A single IL28B genotype SNP rs12979860 determination predicts treatment response in patients with chronic hepatitis C Genotype 1 virus
Published in European journal of gastroenterology & hepatology (01-10-2011)“…BACKGROUNDRecent studies have suggested that host genetics may be useful for predicting drug response and have supported the recommendation that single…”
Get full text
Journal Article -
17
Variants of CTGF are associated with hepatic fibrosis in Chinese, Sudanese, and Brazilians infected with schistosomes
Published in The Journal of experimental medicine (26-10-2009)“…Abnormal fibrosis occurs during chronic hepatic inflammations and is the principal cause of death in hepatitis C virus and schistosome infections. Hepatic…”
Get full text
Journal Article -
18
Analysis of the 5q31-q33 Locus Shows an Association between IL13-1055C/T IL-13-591A/G Polymorphisms and Schistosoma haematobium Infections
Published in The Journal of immunology (1950) (15-05-2005)“…Millions of humans are exposed to schistosome infections, which cause severe kidney and liver disease and 280,000 deaths annually. Th2-mediated immunity is…”
Get full text
Journal Article -
19
A functional promoter variant in IL12B predisposes to cerebral malaria
Published in Human molecular genetics (15-07-2008)“…The role of the Th1 pathway in the pathogenesis of severe malaria is unclear. We recently reported that a polymorphism with increasing IFNG transcription is…”
Get full text
Journal Article -
20
Improved technique that allows the performance of large-scale SNP genotyping on DNA immobilized by FTA ® technology
Published in Infection, genetics and evolution (2007)“…FTA ® technology is a novel method designed to simplify the collection, shipment, archiving and purification of nucleic acids from a wide variety of biological…”
Get full text
Journal Article