Search Results - "Argenty, Jérémy"
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A selective LIS1 requirement for mitotic spindle assembly discriminates distinct T-cell division mechanisms within the T-cell lineage
Published in eLife (15-12-2022)“…The ability to proliferate is a common feature of most T-cell populations. However, proliferation follows different cell-cycle dynamics and is coupled to…”
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THEMIS enhances TCR signaling and enables positive selection by selective inhibition of the phosphatase SHP-1
Published in Nature immunology (01-04-2017)“…Love and colleagues show that THEMIS enhances the TCR signaling response to low-affinity ligands by inhibiting the tyrosine-phosphatase activity of SHP-1…”
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The T cell CD6 receptor operates a multitask signalosome with opposite functions in T cell activation
Published in The Journal of experimental medicine (01-02-2021)“…To determine the respective contribution of the LAT transmembrane adaptor and CD5 and CD6 transmembrane receptors to early TCR signal propagation,…”
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Themis1 enhances T cell receptor signaling during thymocyte development by promoting Vav1 activity and Grb2 stability
Published in Science signaling (17-05-2016)“…The T cell signaling protein Themis1 is essential for the positive and negative selection of thymocytes in the thymus. Although the developmental defect that…”
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Grb2-Mediated Recruitment of USP9X to LAT Enhances Themis Stability following Thymic Selection
Published in The Journal of immunology (1950) (15-10-2017)“…Themis is a new component of the TCR signaling machinery that plays a critical role during T cell development. The positive selection of immature CD4 CD8…”
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Erratum: THEMIS enhances TCR signaling and enables positive selection by selective inhibition of the phosphatase SHP-1
Published in Nature immunology (01-06-2017)“…Nat. Immunol.; doi:10.1038/ni.3692; corrected online 7 March 2017 In the version of this article initially published online, in the second sentence of the…”
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THEMIS enhances TCR signaling and enables positive selection by selective inhibition of SHP-1
Published in Nature immunology (27-02-2017)“…THEMIS, a T cell specific protein that is highly expressed in CD4 + CD8 + thymocytes, has a crucial role in positive selection and T cell development. THEMIS…”
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Quantitative interactomic of CD40 in primary B cells
Published in hLife (01-02-2024)“…Over the past few decades, antibody-based therapies have emerged as an additional tool to treat patients developing cancer and auto-immune diseases. The…”
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