Search Results - "Argentieri, Rochelle L"
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1
Serum amyloid P therapeutically attenuates murine bleomycin-induced pulmonary fibrosis via its effects on macrophages
Published in PloS one (12-03-2010)“…Macrophages promote tissue remodeling but few mechanisms exist to modulate their activity during tissue fibrosis. Serum amyloid P (SAP), a member of the…”
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2
BMP-7 does not protect against bleomycin-induced lung or skin fibrosis
Published in PloS one (29-12-2008)“…Bone morphogenic protein (BMP)-7 is a member of the BMP family which are structurally and functionally related, and part of the TGFbeta super family of growth…”
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3
TGF-beta driven lung fibrosis is macrophage dependent and blocked by Serum amyloid P
Published in The international journal of biochemistry & cell biology (2011)“…The pleiotropic growth factor TGFβ 1 promotes many of the pathogenic mechanisms observed in lung fibrosis and airway remodeling, such as aberrant extracellular…”
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4
Targeting cytosolic phospholipase A2 by arachidonyl trifluoromethyl ketone prevents chronic inflammation in mice
Published in European journal of pharmacology (13-06-2006)“…Cytosolic phospholipase A(2) (cPLA(2)) plays a pivotal role in inflammation by catalyzing the release of arachidonic acid, a substrate for lipoxygenase and…”
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5
BMP-7 fails to attenuate TGF-β1-induced epithelial-to-mesenchymal transition in human proximal tubule epithelial cells
Published in Nephrology, dialysis, transplantation (01-05-2009)“…Background. In rodent models of chronic renal disease bone morphogenetic protein-7 (BMP-7) has been shown to halt disease progression and promote recovery…”
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6
Virtual Screening to Successfully Identify Novel Janus Kinase 3 Inhibitors: A Sequential Focused Screening Approach
Published in Journal of medicinal chemistry (13-11-2008)“…In an effort to identify novel Janus kinase 3 inhibitors, a sequential focused screening approach was adopted to search our in-house chemical database. By…”
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7
Serum amyloid P ameliorates radiation-induced oral mucositis and fibrosis
Published in Fibrogenesis & tissue repair (05-07-2010)“…To evaluate the effect of the anti-fibrotic protein serum amyloid P (SAP) on radiation-induced oral mucositis (OM) and fibrosis in a hamster cheek-pouch model…”
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8
Generation of bleomycin-induced lung fibrosis is independent of IL-16
Published in Cytokine (Philadelphia, Pa.) (01-04-2009)“…Given that CD4+ cells are found in the lungs of patients with fibrotic lung diseases such as idiopathic pulmonary fibrosis (IPF) we hypothesized that IL-16, a…”
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9
Hyper-responsiveness of IPF/UIP fibroblasts: Interplay between TGFβ1, IL-13 and CCL2
Published in The international journal of biochemistry & cell biology (2008)“…One of the hallmarks of idiopathic pulmonary fibrosis with a usual interstitial pneumonia histological pathology (IPF/UIP) is excess collagen deposition, due…”
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10
BMP-7 fails to attenuate TGF- 1-induced epithelial-to-mesenchymal transition in human proximal tubule epithelial cells
Published in Nephrology, dialysis, transplantation (01-05-2009)“…Background. In rodent models of chronic renal disease bone morphogenetic protein-7 (BMP-7) has been shown to halt disease progression and promote recovery…”
Get full text
Journal Article -
11
BMP-7 fails to attenuate TGF-beta1-induced epithelial-to-mesenchymal transition in human proximal tubule epithelial cells
Published in Nephrology, dialysis, transplantation (01-05-2009)“…In rodent models of chronic renal disease bone morphogenetic protein-7 (BMP-7) has been shown to halt disease progression and promote recovery. Subsequent…”
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Journal Article -
12
Hyper-responsiveness of IPF/UIP fibroblasts: interplay between TGFbeta1, IL-13 and CCL2
Published in The international journal of biochemistry & cell biology (2008)“…One of the hallmarks of idiopathic pulmonary fibrosis with a usual interstitial pneumonia histological pathology (IPF/UIP) is excess collagen deposition, due…”
Get full text
Journal Article -
13
Targeting cytosolic phospholipase A 2 by arachidonyl trifluoromethyl ketone prevents chronic inflammation in mice
Published in European journal of pharmacology (2006)“…Cytosolic phospholipase A 2 (cPLA 2) plays a pivotal role in inflammation by catalyzing the release of arachidonic acid, a substrate for lipoxygenase and…”
Get full text
Journal Article