Search Results - "Argemi, Josepmaría"

SPARC inhibition accelerates NAFLD‐associated hepatocellular carcinoma development by dysregulating hepatic lipid metabolism by Onorato, Agostina, Fiore, Esteban, Bayo, Juan, Casali, Cecilia, Fernandez‐Tomé, María, Rodríguez, Marcelo, Domínguez, Luciana, Argemi, Josepmaría, Hidalgo, Florencia, Favre, Cristian, García, Mariana, Atorrasagasti, Catalina, Mazzolini, Guillermo D.

“…Background and aims Non‐alcoholic fatty liver (NAFLD) and its more serious form non‐alcoholic steatohepatitis increase risk of hepatocellular carcinoma (HCC)…”
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Mapping early serum proteome signatures of liver regeneration in living donor liver transplant cases by Carmona‐Rodríguez, Lorena, Gajadhar, Aaron S., Blázquez‐García, Irene, Guerrero, Laura, Fernández‐Rojo, Manuel A., Uriarte, Iker, Mamani‐Huanca, Maricruz, López‐Gonzálvez, Ángeles, Ciordia, Sergio, Ramos, Antonio, Herrero, José Ignacio, Fernández‐Barrena, Maite G., Arechederra, María, Berasain, Carmen, Quiroga, Jorge, Sangro, Bruno, Argemi, Josepmaría, Pardo, Fernando, Rotellar, Fernando, López, Daniel, Barbas, Coral, Ávila, Matías A., Corrales, Fernando J.

“…The liver is the only solid organ capable of regenerating itself to regain 100% of its mass and function after liver injury and/or partial hepatectomy (PH)…”
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Design and validation of a tunable inertial microfluidic system for the efficient enrichment of circulating tumor cells in blood by Rodríguez‐Pena, Alejandro, Armendariz, Estibaliz, Oyarbide, Alvaro, Morales, Xabier, Ortiz‐Espinosa, Sergio, Ruiz‐Fernández de Córdoba, Borja, Cochonneau, Denis, Cornago, Iñaki, Heymann, Dominique, Argemi, Josepmaría, D'Avola, Delia, Sangro, Bruno, Lecanda, Fernando, Pio, Ruben, Cortés‐Domínguez, Iván, Ortiz‐de‐Solórzano, Carlos

“…The analysis of circulating tumor cells (CTCs) in blood is a powerful noninvasive alternative to conventional tumor biopsy. Inertial‐based separation is a…”
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Immunotherapy in HCC—No rush despite the hype by Sangro, Bruno, Argemí, Josepmaria

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Transarterial Radioembolization Ought Not to Borrow Future Liver Function from Patients with Hepatocellular Carcinoma. But Does It? by Sangro, Bruno, Argemí, Josepmaria

“…[Display omitted]…”
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Loss of liver function in chronic liver disease: An identity crisis by Berasain, Carmen, Arechederra, Maria, Argemí, Josepmaria, Fernández-Barrena, Maite G., Avila, Matías A.

“…Adult hepatocyte identity is constructed throughout embryonic development and fine-tuned after birth. A multinodular network of transcription factors, along…”
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Super enhancer regulation of cytokine-induced chemokine production in alcoholic hepatitis by Liu, Mengfei, Cao, Sheng, He, Li, Gao, Jinhang, Arab, Juan P., Cui, Huarui, Xuan, Weixia, Gao, Yandong, Sehrawat, Tejasav S., Hamdan, Feda H., Ventura-Cots, Meritxell, Argemi, Josepmaria, Pomerantz, William C. K., Johnsen, Steven A., Lee, Jeong-Heon, Gao, Fei, Ordog, Tamas, Mathurin, Philippe, Revzin, Alexander, Bataller, Ramon, Yan, Huihuang, Shah, Vijay H.

“…Alcoholic hepatitis (AH) is associated with liver neutrophil infiltration through activated cytokine pathways leading to elevated chemokine expression…”
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Inhibition of HSP90 and Activation of HSF1 Diminish Macrophage NLRP3 Inflammasome Activity in Alcohol‐Associated Liver Injury by Choudhury, Asmita, Bullock, Daniel, Lim, Arlene, Argemi, Josepmaria, Orning, Pontus, Lien, Egil, Bataller, Ramon, Mandrekar, Pranoti

“…Background Activation of NLRP3 in liver macrophages contributes to alcohol‐associated liver disease (ALD). Molecular chaperone heat shock protein (HSP) 90…”
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CRIg on liver macrophages clears pathobionts and protects against alcoholic liver disease by Duan, Yi, Chu, Huikuan, Brandl, Katharina, Jiang, Lu, Zeng, Suling, Meshgin, Nairika, Papachristoforou, Eleni, Argemi, Josepmaria, Mendes, Beatriz G., Wang, Yanhan, Su, Hua, Sun, Weizhong, Llorente, Cristina, Hendrikx, Tim, Liu, Xiao, Hosseini, Mojgan, Kisseleva, Tatiana, Brenner, David A., Bataller, Ramon, Ramachandran, Prakash, Karin, Michael, Fu, Wenxian, Schnabl, Bernd

“…Complement receptor of immunoglobulin superfamily (CRIg) is expressed on liver macrophages and directly binds complement component C3b or Gram-positive…”
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A comprehensive study of epigenetic alterations in hepatocellular carcinoma identifies potential therapeutic targets by Bayo, Juan, Fiore, Esteban J., Dominguez, Luciana M., Real, Alejandrina, Malvicini, Mariana, Rizzo, Manglio, Atorrasagasti, Catalina, García, Mariana G., Argemi, Josepmaria, Martinez, Elisabeth D., Mazzolini, Guillermo D.

“…[Display omitted] •Mutations and expression alterations of epigenetic modifiers are frequent in HCC.•Jumonji lysine demethylase inhibitors normalize aggressive…”
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Serum Transferrin Is an Independent Predictor of Mortality in Severe Alcoholic Hepatitis by Atkinson, Stephen R., Hamesch, Karim, Spivak, Igor, Guldiken, Nurdan, Cabezas, Joaquín, Argemi, Josepmaria, Theurl, Igor, Zoller, Heinz, Cao, Sheng, Mathurin, Philippe, Shah, Vijay H., Trautwein, Christian, Bataller, Ramon, Thursz, Mark R., Strnad, Pavel

“…Severe alcoholic hepatitis (sAH) confers substantial mortality, but the disease course is difficult to predict. As iron parameters are attractive outcome…”
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Validation of a rapid antigen test as a screening tool for SARS-CoV-2 infection in asymptomatic populations. Sensitivity, specificity and predictive values by Fernandez-Montero, Alejandro, Argemi, Josepmaria, Rodríguez, José Antonio, Ariño, Arturo H., Moreno-Galarraga, Laura

“…Early diagnosis of SARS-CoV-2 infection is essential to reduce disease spread. Rapid antigen tests have not been sufficiently evaluated in asymptomatic…”
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Hepatic gap junctions amplify alcohol liver injury by propagating cGAS-mediated IRF3 activation by Luther, Jay, Khan, Sanjoy, Gala, Manish K., Kedrin, Dmitry, Sridharan, Gautham, Goodman, Russell P., Garber, John J., Masia, Ricard, Diagacomo, Erik, Adams, Daniel, King, Kevin R., Piaker, Samuel, Reinecker, Hans-Christian, Yarmush, Martin L., Argemi, Josepmaria, Bataller, Ramon, Dienstag, Jules L., Chung, Raymond T., Patel, Suraj J.

“…Alcohol-related liver disease (ALD) accounts for the majority of cirrhosis and liver-related deaths worldwide. Activation of IFN-regulatory factor (IRF3)…”
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Nivolumab after selective internal radiation therapy for the treatment of hepatocellular carcinoma: a phase 2, single-arm study by de la Torre-Aláez, Manuel, Matilla, Ana, Varela, Maria, Iñarrairaegui, Mercedes, Reig, Maria, Lledó, Jose Luis, Arenas, Juan Ignacio, Lorente, Sara, Testillano, Milagros, Márquez, Laura, Da Fonseca, Leonardo, Argemí, Josepmaria, Gómez-Martin, Carlos, Rodriguez-Fraile, Macarena, Bilbao, Jose I, Sangro, Bruno

“…PurposeTo evaluate the safety and efficacy of selective internal radiation therapy (SIRT) in combination with a PD-1 inhibitor in patients with unresectable…”
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A new animal model of atrophy–hypertrophy complex and liver damage following Yttrium-90 lobar selective internal radiation therapy in rabbits by Páramo, María, Santamaría, Eva, Idoate, Miguel A., Rodríguez-Fraile, Macarena, Benito, Alberto, Collantes, Maria, Quincoces, Gemma, Peñuelas, Iván, Berasain, Carmen, Argemi, Josepmaria, Quiroga, Jorge, Sangro, Bruno, Bilbao, José I., Iñarrairaegui, Mercedes

“…Lobar selective internal radiation therapy (SIRT) is widely used to treat liver tumors inducing atrophy of the treated lobe and contralateral hypertrophy. The…”
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The exposure to uteroplacental insufficiency is associated with activation of unfolded protein response in postnatal life by Deodati, Annalisa, Argemí, Josepmaría, Germani, Daniela, Puglianiello, Antonella, Alisi, Anna, De Stefanis, Cristiano, Ferrero, Roberto, Nobili, Valerio, Aragón, Tomás, Cianfarani, Stefano

“…Early life events are associated with the susceptibility to chronic diseases in adult life. Perturbations of endoplasmic reticulum (ER) homeostasis activate…”
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AG5 is a potent non-steroidal anti-inflammatory and immune regulator that preserves innate immunity by Botella-Asunción, Pablo, Rivero-Buceta, Eva M., Vidaurre-Agut, Carla, Lama, Raquel, Rey-Campos, Magalí, Moreno, Alejandro, Mendoza, Laura, Mingo-Casas, Patricia, Escribano-Romero, Estela, Gutierrez-Adan, Alfonso, Saiz, Juan Carlos, Smerdou, Cristian, Gonzalez, Gloria, Prosper, Felipe, Argemí, Josepmaría, Miguel, Jesus San, Sanchez-Cordón, Pedro J., Figueras, Antonio, Quesada-Gomez, Jose Manuel, Novoa, Beatriz, Montoya, María, Martín-Acebes, Miguel A., Pineda-Lucena, Antonio, Benlloch, Jose María

“…An archetypal anti-inflammatory compound against cytokine storm would inhibit it without suppressing the innate immune response. AG5, an anti-inflammatory…”
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Liver-specific ceramide reduction alleviates steatosis and insulin resistance in alcohol-fed mice[S] by Correnti, Jason, Lin, Chelsea, Brettschneider, Jascha, Kuriakose, Amy, Jeon, Sookyoung, Scorletti, Eleonora, Oranu, Amanke, McIver-Jenkins, Dru, Kaneza, Isabelle, Buyco, Delfin, Saiman, Yedidya, Furth, Emma E., Argemi, Josepmaria, Bataller, Ramon, Holland, William L., Carr, Rotonya M.

“…Alcohol's impairment of both hepatic lipid metabolism and insulin resistance (IR) are key drivers of alcoholic steatosis, the initial stage of alcoholic liver…”
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Serum Acylcarnitines Associated with High Short-Term Mortality in Patients with Alcoholic Hepatitis by Gao, Bei, Argemi, Josepmaria, Bataller, Ramon, Schnabl, Bernd

“…Alcohol-related liver disease is one of the most prevalent liver diseases in the United States. Early stages of alcohol-related liver disease are characterized…”
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Identifying Differentially Expressed MicroRNAs, Target Genes, and Key Pathways Deregulated in Patients with Liver Diseases by Gholizadeh, Maryam, Szelag-Pieniek, Sylwia, Post, Mariola, Kurzawski, Mateusz, Prieto, Jesus, Argemi, Josepmaria, Drozdzik, Marek, Kaderali, Lars

“…Liver diseases are important causes of morbidity and mortality worldwide. The aim of this study was to identify differentially expressed microRNAs (miRNAs),…”
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