Search Results - "Arentson, Benjamin W"

Structures of the PutA peripheral membrane flavoenzyme reveal a dynamic substrate-channeling tunnel and the quinone-binding site by Singh, Harkewal, Arentson, Benjamin W., Becker, Donald F., Tanner, John J.

“…Proline utilization A (PutA) proteins are bifunctional peripheral membrane flavoenzymes that catalyze the oxidation of L-proline to L-glutamate by the…”
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Substrate channeling in proline metabolism by Arentson, Benjamin W, Sanyal, Nikhilesh, Becker, Donald F

“…Proline metabolism is an important pathway that has relevance in several cellular functions such as redox balance, apoptosis, and cell survival. Results from…”
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Structural Basis for the Substrate Inhibition of Proline Utilization A by Proline by Korasick, David A, Pemberton, Travis A, Arentson, Benjamin W, Becker, Donald F, Tanner, John J

“…Proline utilization A (PutA) is a bifunctional flavoenzyme that catalyzes the two-step oxidation of l-proline to l-glutamate using spatially separated proline…”
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Engineering a trifunctional proline utilization A chimaera by fusing a DNA-binding domain to a bifunctional PutA by Arentson, Benjamin W, Hayes, Erin L, Zhu, Weidong, Singh, Harkewal, Tanner, John J, Becker, Donald F

“…Proline utilization A (PutA) is a bifunctional flavoenzyme with proline dehydrogenase (PRODH) and Δ -pyrroline-5-carboxylate (P5C) dehydrogenase (P5CDH)…”
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First evidence for substrate channeling between proline catabolic enzymes: a validation of domain fusion analysis for predicting protein-protein interactions by Sanyal, Nikhilesh, Arentson, Benjamin W, Luo, Min, Tanner, John J, Becker, Donald F

“…Proline dehydrogenase (PRODH) and Δ(1)-pyrroline-5-carboxylate (P5C) dehydrogenase (P5CDH) catalyze the four-electron oxidation of proline to glutamate via the…”
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Structures of Proline Utilization A (PutA) Reveal the Fold and Functions of the Aldehyde Dehydrogenase Superfamily Domain of Unknown Function by Luo, Min, Gamage, Thameesha T., Arentson, Benjamin W., Schlasner, Katherine N., Becker, Donald F., Tanner, John J.

“…Aldehyde dehydrogenases (ALDHs) catalyze the NAD(P)+-dependent oxidation of aldehydes to carboxylic acids and are important for metabolism and detoxification…”
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Crystal Structures and Kinetics of Monofunctional Proline Dehydrogenase Provide Insight into Substrate Recognition and Conformational Changes Associated with Flavin Reduction and Product Release by Luo, Min, Arentson, Benjamin W, Srivastava, Dhiraj, Becker, Donald F, Tanner, John J

“…Proline dehydrogenase (PRODH) catalyzes the FAD-dependent oxidation of proline to Δ1-pyrroline-5-carboxylate, which is the first step of proline catabolism…”
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Kinetic and Structural Characterization of Tunnel-Perturbing Mutants in Bradyrhizobium japonicum Proline Utilization A by Arentson, Benjamin W, Luo, Min, Pemberton, Travis A, Tanner, John J, Becker, Donald F

“…Proline utilization A from Bradyrhizobium japonicum (BjPutA) is a bifunctional flavoenzyme that catalyzes the oxidation of proline to glutamate using fused…”
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Evidence That the C‑Terminal Domain of a Type B PutA Protein Contributes to Aldehyde Dehydrogenase Activity and Substrate Channeling by Luo, Min, Christgen, Shelbi, Sanyal, Nikhilesh, Arentson, Benjamin W, Becker, Donald F, Tanner, John J

“…Proline utilization A (PutA) is a bifunctional enzyme that catalyzes the oxidation of proline to glutamate. Structures of type A PutAs have revealed the…”
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Revealing the function of a linker in the multi‐functional regulatory protein—proline utilization A from Escherichia coli by Mao, Yizi, Arentson, Benjamin W., Becker, Donald F.

“…Abstract only Proline metabolism is critical for several cellular processes such as serving as carbon and nitrogen sources, preventing osmotic stress…”
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First Evidence for Substrate Channeling between Proline Catabolic Enzymes by Sanyal, Nikhilesh, Arentson, Benjamin W., Luo, Min, Tanner, John J., Becker, Donald F.

“…Proline dehydrogenase (PRODH) and Δ1-pyrroline-5-carboxylate (P5C) dehydrogenase (P5CDH) catalyze the four-electron oxidation of proline to glutamate via the…”
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Investigation of proline utilization A: Kinetic analysis of substrate channel-blocking mutants and creation of a trifunctional chimera enzyme by Arentson, Benjamin W

“…Proline metabolism is known to be involved in many cellular processes such as cell signaling, cellular redox balance, and cell survival. One of the enzymes…”
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