Search Results - "Arendt, B K"

Evidence for ongoing DNA damage in multiple myeloma cells as revealed by constitutive phosphorylation of H2AX by Walters, D K, Wu, X, Tschumper, R C, Arendt, B K, Huddleston, P M, Henderson, K J, Dispenzieri, A, Jelinek, D F

“…DNA double-strand breaks (DSBs) are deleterious lesions that can lead to chromosomal anomalies, genomic instability and cancer. The histone protein H2AX has an…”
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Increased expression of extracellular matrix metalloproteinase inducer (CD147) in multiple myeloma: role in regulation of myeloma cell proliferation by Arendt, B K, Walters, D K, Wu, X, Tschumper, R C, Huddleston, P M, Henderson, K J, Dispenzieri, A, Jelinek, D F

“…Multiple myeloma (MM) is preceded by the asymptomatic pre-malignant state, monoclonal gammopathy of undetermined significance (MGUS). Although MGUS patients…”
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Inhibition of survivin expression suppresses the growth of aggressive non-Hodgkin's lymphoma by ANSELL, S. M, ARENDT, B. K, GROTE, D. M, JELINEK, D. F, NOVAK, A. J, WELLIK, L. E, REMSTEIN, E. D, BENNETT, C. F, FIELDING, A

“…Survivin is a member of the inhibitor of apoptosis protein (IAP) family and functions both as an apoptosis inhibitor and a regulator of cell division. Survivin…”
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Interleukin 6 induces monocyte chemoattractant protein-1 expression in myeloma cells by ARENDT, B. K, VELAZQUEZ-DONES, A, TSCHUMPER, R. C, HOWELL, K. G, ANSELL, S. M, WITZIG, T. E, JELINEK, D. F

“…Interleukin 6 (IL-6) is known to play an important role in the biology of the malignant plasma cells in multiple myeloma. In an effort to better understand…”
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A role for insulin-like growth factor in the regulation of IL-6- responsive human myeloma cell line growth by Jelinek, DF, Witzig, TE, Arendt, BK

“…Insulin-like growth factors (IGF-I, IGF-II) have long been recognized as important mitogens in many types of malignancies. Because the role of IGFs in growth…”
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Atypical expression of ErbB3 in myeloma cells: cross-talk between ErbB3 and the interferon-α signaling complex by WALTERS, Denise K, FRENCH, Jena D, ARENDT, Bonnie K, JELINEK, Diane F

“…We have previously demonstrated that the responsiveness of multiple myeloma (MM) cells to interferon-alpha (IFN-alpha) stimulation is variable, with an…”
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Differential human multiple myeloma cell line responsiveness to interferon-alpha. Analysis of transcription factor activation and interleukin 6 receptor expression by Jelinek, D F, Aagaard-Tillery, K M, Arendt, B K, Arora, T, Tschumper, R C, Westendorf, J J

“…Although IFN-alpha is commonly used as maintenance treatment for multiple myeloma patients, its effectiveness is varied. In this study, we have used a panel of…”
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Differential human multiple myeloma cell line responsiveness to interferon-alpha. Analysis of transcription factor activation and interleukin 6 receptor expression by Jelinek, D F, Aagaard-Tillery, K M, Arendt, B K, Arora, T, Tschumper, R C, Westendorf, J J

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Expression of BCMA, TACI, and BAFF-R in multiple myeloma: a mechanism for growth and survival by Novak, Anne J., Darce, Jaime R., Arendt, Bonnie K., Harder, Brandon, Henderson, Kathy, Kindsvogel, Wayne, Gross, Jane A., Greipp, Philip R., Jelinek, Diane F.

“…Multiple myeloma (MM) is a progressive disease that is thought to result from multiple genetic insults to the precursor plasma cell that ultimately affords the…”
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