Search Results - "Arends, M.J"
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Multiple-instance-learning-based detection of coeliac disease in histological whole-slide images
Published in Journal of pathology informatics (01-01-2022)“…We present a multiple-instance-learning-based scheme for detecting coeliac disease, an autoimmune disorder affecting the intestine, in histological whole-slide…”
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38 Uncoupling of GTP hydrolysis from eIF6 release on the ribosome causes Shwachman-Diamond syndrome
Published in Leukemia research (2011)Get full text
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Multiple high risk HPV infections are common in cervical neoplasia and young women in a cervical screening population
Published in Journal of clinical pathology (01-01-2004)“…Aims: If human papillomavirus (HPV) testing is to be included within cervical screening programmes, the importance of multiple HPV infections in cervical…”
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The activating mutation R201C in GNAS promotes intestinal tumourigenesis in [Apc.sup.Min/+] mice through activation of Wnt and ERK1/2 MAPK pathways
Published in Oncogene (12-08-2010)“…Somatically acquired, activating mutations of GNAS, the gene encoding the stimulatory G-protein Gsa subunit, have been identified in kidney, thyroid,…”
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Jdp2 downregulates Trp53 transcription to promote leukaemogenesis in the context of Trp53 heterozygosity
Published in Oncogene (17-01-2013)“…We performed a genetic screen in mice to identify candidate genes that are associated with leukaemogenesis in the context of Trp53 heterozygosity. To do this…”
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Loss of Rassf1a cooperates with [Apc.sup.Min] to accelerate intestinal tumourigenesis
Published in Oncogene (24-07-2008)Get full text
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Loss of Rassf1a co-operates with ApcMin to accelerate intestinal tumourigenesis
Published in Oncogene (07-04-2008)“…Promoter methylation of the RAS-association domain family 1, isoform A gene ( RASSF1A ) is one of the most frequent events found in human tumours. In this…”
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Pathology of the appendix
Published in Current diagnostic pathology (01-10-2007)Get full text
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Unusual Causes of Colonic Wall Thickening on Computed Tomography
Published in Clinical Radiology (01-03-2003)“…Computed tomography (CT) appearances in “colitis” are often non-specific, and include mural thickening and mesenteric fat stranding. In the western world, the…”
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Tamoxifen increases apoptosis but does not influence markers of proliferation in an MCF-7 xenograft model of breast cancer
Published in Breast (Edinburgh) (01-04-2000)“…Twenty-four nude mice bearing MCF-7 breast cancer cells grown as xenografts and treated with tamoxifen (2.5 mg slow-release pellet) were studied for up to 35…”
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The apoptosis-inducing effects of polyunsaturated fatty acids (PUFAs) on benign and malignant breast cells in vitro
Published in Breast (Edinburgh) (01-02-1999)“…Three breast cell lines, the malignant MCF-7 and MDA-MB-231 and the immortalized but non-malignant HBL-100 lines, were growth-inhibited in vitro by the…”
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Recombinant DNA technology and its diagnostic applications
Published in Histopathology (01-10-1992)“…As yet recombinant DNA technology does not appear to have widespread diagnostic application in pathology. However, it does have a useful role to play in…”
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A PCR approach to discriminate between integrated and episomal HPV DNA in small clinical specimens
Published in Molecular and cellular probes (01-08-1993)“…HPV infection has long been implicated in the development of cervical carcinoma. There is strong evidence for association of high-risk HPV types 16 and 18 with…”
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