Search Results - "Areg A. Totolian"
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Macrophage-Derived Chemokine MDC/CCL22: An Ambiguous Finding in COVID-19
Published in International journal of molecular sciences (23-08-2023)“…Macrophage-derived chemokine (MDC/CCL22) is a chemokine of the C-C subfamily. It is involved in T-cellular maturation and migration. Our previous research…”
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Role of IL-27 in COVID-19: A Thin Line between Protection and Disease Promotion
Published in International journal of molecular sciences (21-07-2024)“…Cytokine storm is usually described as one of the main reasons behind COVID-associated mortality. Cytokines are essential protein molecules engaged in immune…”
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MDC/CCL22 depletion in COVID-19 and post-COVID
Published in Medit͡s︡inskai͡a︡ immunologii͡a (01-06-2023)“…In this article, we explore the role of macrophage-derived chemokine (MDC/CCL22) in COVID-19 immunity. The study included plasma samples of 289 patients with…”
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Cytokine Profiling in Different SARS-CoV-2 Genetic Variants
Published in International journal of molecular sciences (16-11-2022)“…This study is a successor of our previous work concerning changes in the chemokine profile in infection that are associated with different SARS-CoV-2 genetic…”
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CX3CL1/Fractalkine: A Potential Biomarker for Liver Fibrosis in Chronic HBV Infection
Published in Current issues in molecular biology (10-09-2024)“…A hepatitis B virus (HBV) infection can progress to chronic hepatitis, leading to liver fibrosis, cirrhosis, and hepatocellular carcinoma. CX3CL1/Fractalkine…”
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Apoptotic Receptors and CD107a Expression by NK Cells in an Interaction Model with Trophoblast Cells
Published in Current issues in molecular biology (01-08-2024)“…Natural killer cells (NK cells) exert cytotoxicity towards target cells in several ways, including the expression of apoptosis-mediating ligands (TRAIL, FasL)…”
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A Comparative Study of the Plasma Chemokine Profile in COVID-19 Patients Infected with Different SARS-CoV-2 Variants
Published in International journal of molecular sciences (13-08-2022)“…Background. Infection caused by SARS-CoV-2 mostly affects the upper and lower respiratory tracts and causes symptoms ranging from the common cold to pneumonia…”
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COVID-19 Incidence Proportion as a Function of Regional Testing Strategy, Vaccination Coverage, and Vaccine Type
Published in Viruses (30-10-2023)“…The COVID-19 pandemic has become a serious challenge for humanity almost everywhere globally. Despite active vaccination around the world, the incidence…”
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HIV Drug Resistance Mutations and Subtype Profiles among Pregnant Women of Ho Chi Minh City, South Vietnam
Published in Viruses (27-09-2023)“…According to the latest data released by UNAIDS, the global number of people living with HIV (PLHIV) in 2021 was 38.4 million, with 1.5 million new HIV…”
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CXCR3-Expressing T Cells in Infections and Autoimmunity
Published in Frontiers in bioscience (Landmark. Print) (22-08-2024)“…The chemokine receptor CXCR3 and its ligands (MIG/CXCL9, IP-10/CXCL10, and I-TAC/CXCL11) play a central role in the generation of cellular inflammation, both…”
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Resistance Mutation Patterns among HIV-1-Infected Children and Features of the Program for Prevention of Mother-to-Child Transmission in Vietnam's Central Highlands and Southern Regions, 2017-2021
Published in Viruses (01-05-2024)“…The Vietnam Ministry of Health (MOH) has intensified efforts in its aim to eliminate AIDS by 2030. Expanding the program for prevention of mother-to-child…”
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Some opportunities for immunotherapy in coronavirus infection
Published in Infekt͡s︡ii͡a︡ i immunitet (01-08-2020)“…Here we review means of immunomodulatory therapy for coronavirus infection caused by SARS-CoV-2 (COVID-19). It has been appreciated that highly limited arsenal…”
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T helper cell subsets and related target cells in acute COVID-19
Published in Infekt͡s︡ii͡a︡ i immunitet (04-07-2022)“…Current review presents a brief overview of the immune system dysregulation during acute COVID-19 and illustrates the main alterations in peripheral blood CD4+…”
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Changes in Anti-SARS-CoV-2 IgG Subclasses over Time and in Association with Disease Severity
Published in Viruses (29-04-2022)“…IgG is the most prominent marker of post-COVID-19 immunity. Not only does this subtype mark the late stages of infection, but it also stays in the body for a…”
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Longitudinal Randomized Cohort Study of SARS-CoV-2 Antibody Seroprevalence in the St. Petersburg Population
Published in Viruses (27-04-2022)“…Introduction. Since the detection of the first COVID-19 patient, 2 years have passed, during which more than 287,862,000 people have fallen ill globally, of…”
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SARS-CoV-2 Seroprevalence Structure of the Russian Population during the COVID-19 Pandemic
Published in Viruses (19-08-2021)“…The SARS-CoV-2 pandemic, which came to Russia in March 2020, is accompanied by morbidity level changes and can be tracked using serological monitoring of a…”
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Alterations in B Cell and Follicular T-Helper Cell Subsets in Patients with Acute COVID-19 and COVID-19 Convalescents
Published in Current issues in molecular biology (30-12-2021)“…Background. Humoral immunity requires interaction between B cell and T follicular helper cells (Tfh) to produce effective immune response, but the data…”
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Experience with HCV Detection and Molecular Genetic Characterization among Otherwise Healthy Pregnant Women and Their Partners in the Republic of Guinea
Published in Microorganisms (Basel) (27-09-2024)“…According to recent data, there are currently 170 to 200 million people infected with HCV worldwide, and the number of new cases annually is approximately…”
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JUBILEE 2018: 110th ANNIVERSARY OF THE FOUNDATION OF THE ST. PETERSBURG PASTEUR RESEARCH INSTITUTE OF EPIDEMIOLOGY AND MICROBIOLOGY AND THE 95th ANNIVERSARY OF THE NAMING OF THE INSTITUTE AFTER PASTEUR
Published in Infekt͡s︡ii͡a︡ i immunitet (30-12-2018)“…The article presents not previously published archive data and copies of documents about Lieberman Yakov Yulievich, the first director of the Petrograd…”
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Patterns in the development of collective immunity to SARS-CoV-2 during the COVID-19 pandemic
Published in Medit͡s︡inskai͡a︡ immunologii͡a (01-06-2023)“…The ongoing coronavirus disease (COVID-19) pandemic over the past three years has caused close attention to the problem of herd immunity, which is understood…”
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