Search Results - "Arefieva, T I"

Ingramon, a Peptide Inhibitor of MCP-1 Chemokine, Reduces Migration of Blood Monocytes Stimulated by Glioma-Conditioned Medium by Krasnikova, T. L., Arefieva, T. I., Pylaeva, E. A., Sidorova, M. V.

“…Malignant gliomas are most common and fatal primary brain tumors. In addition to neoplastic cells, the tumor tissue contains microglial cells and…”
Get full text

Lipoprotein(a), its autoantibodies, and circulating T lymphocyte subpopulations as independent risk factors for coronary artery atherosclerosis by Afanasievа, O I, Pylaeva, E A, Klesareva, E A, Potekhina, A V, Provatorov, S I, Afanasieva, M I, Krasnikova, T L, Masenko, V P, Arefieva, T I, Pokrovsky, S N

“…To study the role of lipoprotein(a) [Lp(a)] as a potential autoantigen causing the activation of immunocompetent cells in atherosclerosis. A total of 104 men…”
Get full text

Synthetic peptide fragment (65–76) of monocyte chemotactic protein-1 (MCP-1) inhibits MCP-1 binding to heparin and possesses anti-inflammatory activity in stable angina patients after coronary stenting by Arefieva, T. I., Krasnikova, T. L., Potekhina, A. V., Ruleva, N. U., Nikitin, P. I., Ksenevich, T. I., Gorshkov, B. G., Sidorova, M. V., Bespalova, Zh. D., Kukhtina, N. B., Provatorov, S. I., Noeva, E. A., Chazov, E. I.

“…Objective and design The peptide from C-terminal domain of MCP-1 (Ingramon) has been shown to inhibit monocyte migration and possess anti-inflammatory activity…”
Get full text

Immunotropic Effects and Proposed Mechanism of Action for 3-Hydroxy-3-methylglutaryl-coenzyme A Reductase Inhibitors (Statins) by Arefieva, T. I., Filatova, A. Yu, Potekhina, A. V., Shchinova, A. M.

“…Inhibitors of HMG-CoA reductase (statins) are the major group of lipid-lowering drugs. Along with hypocholesterolemic activity, statins exhibit…”
Get full text

Immunoinflammatory Aspects of Parkinson’s Disease by Belova, O. V., Arefieva, T. I., Moskvina, S. N.

“…This review analyzes immunological impairments in Parkinson’s disease (PD). We present data on neuroinflammation, with which cell degeneration in the…”
Get full text

Biodegradable Microparticles with Encapsulated Anti-Inflammatory Peptide Ingramon by Marmiy, N. V., Arefieva, T. I., Esipov, D. S., Tashlitsky, V. N., Kozhokar, U. S., Ovchinnikov, M. V., Radyukhina, N. V., Sidorova, M. V.

“…A technique for encapsulating the anti-inflammatory dodecapeptide ingramon into microspheres of a biodegradable copolymer of lactic and glycolic acids (PLGA)…”
Get full text

The Molecular and Cellular Mechanisms Associated with a Microvascular Inflammation in the Pathogenesis of Heart Failure with Preserved Ejection Fraction by Ovchinnikov, A G, Arefieva, T I, Potekhina, A V, Filatova, A Yu, Ageev, F T, Boytsov, S A

“…Heart failure with preserved ejection fraction (HFpEF) is a severe disease with an often unfavorable outcome. The prevalence of HFpEF continues to increase,…”
Get full text

Expression of Markers of Regulatory CD4⁺CD25⁺foxp3⁺ Cells in Atherosclerotic Plaques of Human Coronary Arteries by Sokolov, V. O, Krasnikova, T. L, Prokofieva, L. V, Kukhtina, N. B, Arefieva, T. I

“…The content of marker foxp3 of regulatory T cells and chemokines in atherosclerotic plaques of human coronary arteries was measured by the polymerase chain…”
Get full text

Lipoprotein(a) concentration and the blood content of INFγ-producing T-helpers 17 (Th17/1) in males with premature coronary artery disease by Filatova, A. Yu, Afanasieva, O. I., Arefieva, T. I., Klesareva, E. A., Tyurina, A. V., Ezhov, M. V., Pokrovsky, S. N.

“…Aim . To analyze the relationship of blood lipid profile parameters, including the level of lipoprotein(a) (Lp(a)), and the content of circulating CD4+…”
Get full text

Effect of atorvastatin and rosuvastatin on the PCSK9 blood concentration in statin-naive patients with atherosclerosis by Filatova, A. Yu, Arefieva, T. I., Klesareva, E. A., Afanasieva, O. I.

“…Statins are currently the main group of lipid-lowering drugs used in clinical practice. However not all patients manage to achieve ‘target’ levels of LDL. A…”
Get full text

Optimization of the Solid Phase Synthesis of the Ingramon Peptide Antagonist of the Human Monocyte Chemoattractant Protein 1 (MCP-1) by Sidorova, M. V., Dudkina, U. S., Avdeev, D. V., Palkeeva, M. E., Molokoedov, A. S., Ovchinnikov, M. V., Azmuko, A. A., Grechishnikov, S. B., Kudryavtseva, E. V., Bushuev, V. N., Arefieva, T. I.

“…— The solid phase synthesis (SPS) of the ingramon peptide antagonist of the human monocyte chemoattractant protein-1…”
Get full text

THE INFLUENCE OF ATORVASTATIN AND ROSUVASTATIN IN ATHEROSCLEROSIS ON THE PARAMETERS OF CELLULAR IMMUNITY AND IN VITRO LEUCOCYTE ACTIVATION by Filatova, A. Yu, Potekhina, A. V., Ruleva, N. Yu, Radyukhina, N. V., Arefieva, T. I.

“…Aim. To compare the influence of “lipophilic” atorvastatin and “hydrophilic” rosuvastatin on the parameters of cellular immunity in atherosclerosis patients…”
Get full text

Cysteine-Containing Peptides Stimulate Monocyte Migration through NADPH-Oxidase Activation by Krasnikova, T. L., Arefieva, T. I., Pylaeva, E. A., Sidorova, M. V.

“…We analyzed migration of monocytes under the effect of apocinin (NADPH inhibitor) and PD98059 (blocker of extracellular MEK/ERK kinase involved in Nox4…”
Get full text

The severity of internal carotid artery stenosis is associated with the circulating Th17 level by Filatova, A.Yu, Potekhina, A.V., Pylaeva, E.A., Osokina, A.K., Ruleva, N.Yu, Pogorelova, O.A., Tripoten, M.I., Noeva, E.A., Balakhonova, T.V., Masenko, V.P., Arefieva, T.I.

“…Immune and inflammatory reactions contribute to the progression of atherosclerosis. The walls of the different arteries and segments of the arteries have…”
Get full text

Analysis of the causes of repeat stenosis of the coronary arteries after elective stenting in patients with stable angina pectoris by Filatova, A Y, Osokina, A K, Potekhina, A V, Romasov, I V, Kotkina, T I, Shchinova, A M, Noeva, E A, Arefieva, T I, Barabanova, E A, Merkulov, E V, Samko, A N, Provatorov, S I

“…Coronary stenting is the evidence-based treatment approach of stable angina. The objective was to determine the incidence of restenosis or atherosclerosis…”
Get full text

Preprocedural high - sensitivity C-reactive protein (hsCRP) decrease during intensive atorvastatin therapy: the presumable impact on atherosclerosis progression after coronary stenting by Shchinova, A M, Shlevkova, G V, Filatova, A Yu, Potekhina, A V, Osokina, A K, Romasov, I V, Zharova, E A, Noeva, E A, Samko, A N, Masenko, V P, Arefieva, T I, Provatorov, S I

“…Proinflammatory status is the risk factor for coronary atherosclerosis progression after coronary stenting (CS). Intensive statin treatment is associated with…”
Get full text

Intracellular signal cascade in CD4+ T-lymphocyte migration stimulated by interferon-gamma-inducible protein-10 by Kukhtina, N B, Arefieva, T I, Krasnikova, T L

“…The intracellular signal cascades involved in chemokine-stimulated migration of in vitro activated human peripheral blood CD4+ T-lymphocytes were investigated…”
Get full text

Inhibitor of inflammation, peptide fragment (65–76) of monocyte chemotactic protein-1 (MCP-1), inhibits binding of MCP-1 to heparin by Krasnikova, T. L., Nikitin, P. I., Ksenevich, T. I., Gorshkov, S. G., Bushueva, T. L., Arefieva, T. I., Ruleva, N. Yu, Sidorova, M. V., Azmuko, A. A., Bespalova, Zh. D.

“…Monocyte chemotactic protein-1 (MCP-1, CCL2) is one of the most important chemokines involved in inflammation. MCP-1 stimulates migration of monocytes and…”
Get full text

Subpopulation Composition of CD4+ T-lymphocytes as Factor Contributing to the Progression of Atherosclerosis of Carotid Arteries by Filatova, A Yu, Pylaeva, E A, Potekhina, A V, Osokina, A K, Pogorelova, O A, Tripoten, M I, Balakhonova, T V, Provatorov, S I, Noeva, E A, Klesareva, E A, Afanasieva, O I, Arefieva, T I

“…to assess prognostic significance of blood content of regulatory and effector T-lymphocytes for progression of atherosclerosis (AS) of carotid arteries. We…”
Get more information

Peptide fragment 29–40 of amino acid sequence of monocyte chemoattractant protein-1 (MCP-1) stimulates monocyte migration in vivo and facilitates wound healing by Arefieva, T. I., Sokolov, V. O., Pylaeva, E. A., Kukhtina, N. B., Potekhina, A. V., Ruleva, N. Yu, Sidorova, M. V., Bespalova, Zh. D., Azmuko, A. A., Krasnikova, T. L.

Get full text