Search Results - "Ardley, Tiffany"
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Synthesis of new analogs of N-substituted(benzoylamino)-1,2,3,6-tetrahydropyridines
Published in Open Chemistry (09-04-2024)“…The tetrahydropyridine (THP) moiety is notably present in synthetic and natural products, playing a cardinal role in the food, cosmetic, and pharmaceutical…”
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Synthesis of N-Substituted Carbonylamino-1,2,3,6-tetrahydropyridines as Potential Anti-Inflammatory Agents
Published in Synthetic communications (01-01-2011)“…Several N-substituted carbonyl/sulfonylamino-1,2,3,6-tetrahydropyridines (5a-i and 9a, b) were synthesized via sodium borohydride reduction of the…”
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Lead Optimization of Tetrahydropyridines as Potential Breast Cancer Agents
Published in American journal of pharmaceutical education (01-09-2024)Get full text
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Abstract C25: Synthesis of N-substituted [benzoylamino]-5-ethyl-1,2,3,6-tetrahydropyridines as potential anticancer agents
Published in Cancer epidemiology, biomarkers & prevention (01-11-2014)“…Prostate cancer (PC) is a cancer that forms in the tissues of the prostate which is a gland in the male reproductive system found below the bladder and in…”
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Abstract PO-103: Design and synthesis of tetrahydropyridine analogs as selective COX-2 inhibitors and anti-breast cancer agents
Published in Cancer epidemiology, biomarkers & prevention (01-01-2022)“…According to the World Health Organization, breast cancer has become the most common cancer globally as of 2021, accounting for 12% of all new annual cancer…”
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Abstract 3252: Synthesis of N-substituted [Benzoylamino]-3-Ethyl-1,2,3,6-tetrahydropyridines as potential anti-cancer agents
Published in Cancer research (Chicago, Ill.) (01-07-2017)“…Chronic inflammation is believed to promote cancer through cellular and genomic damage. Inflammation creates a microenvironment within the tissue that enhances…”
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Abstract 3102: Synthesis of N-benzoylamino-tetrahydropyridine analogues as selective COX-2 inhibitors and anti-breast cancer agents
Published in Cancer research (Chicago, Ill.) (04-04-2023)“…The World Health Organization confirms breast cancer as the most common cancer globally, as of 2021, tallying 12% of new annual cancer cases. Female breast…”
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Diallyl trisulfide as an inhibitor of benzo(a)pyrene-induced precancerous carcinogenesis in MCF-10A cells
Published in Food and chemical toxicology (01-07-2012)“…► BaP induces changes in cell viability and cell growth in MCF-10A cells. ► BaP induces peroxide formation and DNA strand breaks in MCF-10A cells. ► DATS…”
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Abstract 3903: Synthesis of substituted N-{4-[(2-hydroxyethyl)sulfanyl]-3,6-dihydropyridin-1(2h)-yl} benzamide/benzenesulfonamide as antiinflamatory and anticancer agents
Published in Cancer research (Chicago, Ill.) (15-04-2012)“…Breast cancer is the most common type of cancer among women in the industrialized world, accounting for nearly one of every three cancers diagnosed. There is a…”
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Abstract 3263: Synthesis of substituted N-(4-(6-methyl-1H-benzo[d]imidazol-2-yl)-5,6-dihydropyridin-1(2H)-yl) benzamide/benzenesulfonamide as anticancer agents
Published in Cancer research (Chicago, Ill.) (15-04-2011)“…There is a strong association between chronic inflammatory conditions in a particular organ and the incidence of cancer specific to that organ. The longer the…”
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Abstract 1369: Synthesis of substituted N-[(3-(1H-pyrrol-1yl)methyl]-5,6-dihydropyridin-1(2H)-yl) benzamide/benzene sulfonamide as anticancer agents
Published in Cancer research (Chicago, Ill.) (15-04-2011)“…Cancer has proven to be one of the most intractable human diseases, and as yet no anticancer agents that are highly effective and safe are available…”
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Abstract 735: Synthesis of substituted 1,2,3,4-tetrahydroisoquinolines as anticancer agents
Published in Cancer research (Chicago, Ill.) (15-04-2010)“…The 1,2,3,4-tetrahydroisoquinoline moiety is commonly found in biologically active molecules of either natural or synthetic origin, making its derivatives…”
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Attenuation of Early Benzo(a)Pyrene-Induced Carcinogenic Insults by Diallyl Disulfide (DADS) in MCF-10A Cells
Published in Nutrition and cancer (01-10-2012)“…Diallyl disulfide (DADS), a garlic organosulfur compound, has been researched as a cancer prevention agent; however, the role of DADS in the suppression of…”
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Synthesis of 2-(N-benzylpyrrolyl)-benzimidazoles using polyphosphoric acid prompted cyclocondensation
Published in Journal of heterocyclic chemistry (01-11-2010)“…Synthesis of a series of 2‐substituted benzimidazoles was carried out for screening anti‐inflammatory activities. 2‐(N‐benzylpyrrolyl)‐benzimidazoles 9a, 9b,…”
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The program of excellence in STEM: Involvement of traditionally underrepresented students in STEM education through research and mentoring at Florida A&M University
Published in 2015 IEEE Integrated STEM Education Conference (01-03-2015)“…In its first year of existence, the Program of Excellence in STEM (PE-STEM) at Florida A&M University (FAMU) is designed to provide a model for increasing the…”
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