Search Results - "Ardelli, B.F."

ABC transporters influence sensitivity of Brugia malayi to moxidectin and have potential roles in drug resistance by Stitt, L.E., Tompkins, J.B., Dooley, L.A., Ardelli, B.F.

“…[Display omitted] ► ABC systems impact heath and illness by mediating multidrug resistance (MDR) via overexpression. ► ABC systems that confer MDR are found in…”
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Reduced genetic variation of an Onchocerca volvulus ABC transporter gene following treatment with ivermectin by Ardelli, B.F., Prichard, R.K.

“…In some trichostrongyloid nematodes, the early stages of ivermectin (IVM) resistance have been characterized by a shift in allele frequency and reduced…”
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Brugia malayi: In vitro effects of ivermectin and moxidectin on adults and microfilariae by Tompkins, J.B., Stitt, L.E., Ardelli, B.F.

“…The effect of ivermectin and moxidectin on the motility of Brugia malayi adults and microfilariae and on the fertility of B. malayi females was examined…”
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Host ABC transporter proteins may influence the efficacy of ivermectin and possibly have broader implications for the development of resistance in parasitic nematodes by Dooley, L.A., Froese, E.A., Chung, Y.T., Burkman, E.J., Moorhead, A.R., Ardelli, B.F.

“…ABC transporter proteins function to extrude compounds from the cell. These proteins present an obstacle for treatment and for overcoming drug resistance as…”
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Protective antibodies and anamnestic response in Salvelinus fontinalis to Cryptobia salmositica and innate resistance of Salvelinus namaycush to the hemoflagellate by Ardelli, B.F, Woo, P.T.K

“…Cryptobia-susceptible Salvelinus fontinalis vaccinated with a live Cryptobia salmositica vaccine were protected against C. salmositica and they were still…”
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In vitro secretion of metabolic end-products by piscine haemoflagellates Cryptobia salmositica and C. bullocki (Kinetoplastida: Bodonidae) and the relationship of these products to the pH in the medium by Ardelli, B.F, Woo, P.T.K. (University of Guelph (Canada). Dept. of Zoology and Axelrod Inst. of Ichthyology)

“…Pathogenic and nonpathogenic strains of Cryptobia salmositica and C. bullocki produced hydrogen peroxide, pyruvate and lactate under in vitro conditions in…”
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Improved culture media for piscine hemoflagellates, Cryptobia and Trypanosoma (Kinetoplastida) by Ardelli, B.F, Woo, P.T.K

“…Increasing the Hepes buffer in minimum essential medium from 25 mM to 100 mM yielded a significantly larger number of Cryptobia salmositica. Cryptobia…”
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Identification of variant ABC-transporter genes among Onchocerca volvulus collected from ivermectin-treated and untreated patients in Ghana, West Africa by Ardelli, B.F., Prichard, R.K.

“…Treatment with ivermectin (IVM) is known to cause a loss of polymorphism at certain loci of the β-tubulin, γ-aminobutyric-acid-receptor,…”
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The in vitro effects of crystal violet on the pathogenic haemoflagellate Cryptobia salmositica Katz, 1951 (Sarcomastigophora: Kinetoplastida) by Ardelli, B F, Woo, P T

“…Crystal violet does not inhibit in vitro multiplication of a nonpathogenic strain of Cryptobia salmositica at low concentrations (0.01 microM and 0.001 microM)…”
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