Search Results - "Arcuri, Karen E"

Tick anticoagulant peptide (TAP) is a novel inhibitor of blood coagulation factor Xa by Waxman, L. (Merck Sharp and Dohme Research Laboratories, West Point, PA), Smith, D.E, Arcuri, K.E, Vlasuk, G.P

“…A low molecular weight serine protease inhibitor (TAP) was purified from extracts of the soft tick, Ornithodoros moubata. The peptide is a slow, tight-binding…”
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A Randomized, Placebo-Controlled, Double-Blind, Parallel Study of Various Doses of Losartan Potassium Compared With Enalapril Maleate in Patients With Essential Hypertension by Gradman, Alan H, Arcuri, Karen E, Goldberg, Allan I, Ikeda, Leila S, Nelson, Edward B, Snavely, Duane B, Sweet, Charles S

“…The efficacy and safety of various doses of losartan potassium, a specific and selective angiotensin II receptor antagonist, were compared with those of…”
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Controlled trial of losartan given concomitantly with different doses of hydrochlorothiazide in hypertensive patients by Ruilope, L M, Simpson, R L, Toh, J, Arcuri, K E, Goldberg, A I, Sweet, C S

“…The purpose of this trial was to evaluate the antihypertensive efficacy of the concomitant administration of selected doses of hydrochlorothiazide (HCTZ) on a…”
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Comparative antihypertensive effects of losartan 50 mg and losartan 50 mg titrated to 100 mg in patients with essential hypertension by Ikeda, L S, Harm, S C, Arcuri, K E, Goldberg, A I, Sweet, C S

“…The antihypertensive activity of losartan potassium (losartan, Cozaar), an angiotensin II receptor antagonist, was evaluated in a parallel 12-week,…”
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Binding and internalization of atrial natriuretic factor by high-affinity receptors in A10 smooth muscle cells by Napier, M A, Arcuri, K E, Vandlen, R L

“…A10 smooth muscle cells, derived from embryonic rat thoracic aorta, responded to the atrial natriuretic factor (ANF) with increased levels of cyclic GMP. These…”
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Thioester chromogenic substrates for human factor VIIa: substituted isocoumarins are inhibitors of factor VIIa and in vitro anticoagulants by Kam, C M, Vlasuk, G P, Smith, D E, Arcuri, K E, Powers, J C

“…Arginine thiobenzyl esters are convenient chromogenic substrates of factor VIIa (Z-Arg-SBzl, Kcat/KM = 1,600 M-1 s-1) and were used to study the kinetics of…”
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Functional multiplicity of atrial natriuretic peptide receptors on cultured rat Leydig tumor cells by Vlasuk, George P., Arcuri, Karen E., Ciccarone, Terry M., Nutt, Ruth F.

“…Native rat atrial natriuretic peptide (NANP) was shown to bind with high affinity and to increase intracellular levels of cGMP in cultured rat Leydig tumor…”
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Losartan and low-dose hydrochlorothiazide in patients with essential hypertension. A double-blind, placebo-controlled trial of concomitant administration compared with individual components by MacKay, J H, Arcuri, K E, Goldberg, A I, Snapinn, S M, Sweet, C S

“…Angiotensin II acts at the cellular level through specific angiotensin II subtype I, AT-1 receptors. Losartan is the first of a new class of antihypertensive…”
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