Search Results - "Archives of General Psychiatry"

A randomized controlled trial of the tumor necrosis factor antagonist infliximab for treatment-resistant depression: the role of baseline inflammatory biomarkers by Raison, Charles L, Rutherford, Robin E, Woolwine, Bobbi J, Shuo, Chen, Schettler, Pamela, Drake, Daniel F, Haroon, Ebrahim, Miller, Andrew H

“…Increased concentrations of inflammatory biomarkers predict antidepressant nonresponse, and inflammatory cytokines can sabotage and circumvent the mechanisms…”
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The psychosis high-risk state: a comprehensive state-of-the-art review by Fusar-Poli, Paolo, Borgwardt, Stefan, Bechdolf, Andreas, Addington, Jean, Riecher-Rössler, Anita, Schultze-Lutter, Frauke, Keshavan, Matcheri, Wood, Stephen, Ruhrmann, Stephan, Seidman, Larry J, Valmaggia, Lucia, Cannon, Tyrone, Velthorst, Eva, De Haan, Lieuwe, Cornblatt, Barbara, Bonoldi, Ilaria, Birchwood, Max, McGlashan, Thomas, Carpenter, William, McGorry, Patrick, Klosterkötter, Joachim, McGuire, Philip, Yung, Alison

“…During the past 2 decades, a major transition in the clinical characterization of psychotic disorders has occurred. The construct of a clinical high-risk (HR)…”
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Traffic-related air pollution, particulate matter, and autism by Volk, Heather E, Lurmann, Fred, Penfold, Bryan, Hertz-Picciotto, Irva, McConnell, Rob

“…Autism is a heterogeneous disorder with genetic and environmental factors likely contributing to its origins. Examination of hazardous pollutants has suggested…”
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Microglial activation in young adults with autism spectrum disorder by Suzuki, Katsuaki, Sugihara, Genichi, Ouchi, Yasuomi, Nakamura, Kazuhiko, Futatsubashi, Masami, Takebayashi, Kiyokazu, Yoshihara, Yujiro, Omata, Kei, Matsumoto, Kaori, Tsuchiya, Kenji J, Iwata, Yasuhide, Tsujii, Masatsugu, Sugiyama, Toshirou, Mori, Norio

“…A growing body of evidence suggests that aberrant immunologic systems underlie the pathophysiologic characteristics of autism spectrum disorder (ASD). However,…”
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Fecundity of patients with schizophrenia, autism, bipolar disorder, depression, anorexia nervosa, or substance abuse vs their unaffected siblings by Power, Robert A, Kyaga, Simon, Uher, Rudolf, MacCabe, James H, Långström, Niklas, Landen, Mikael, McGuffin, Peter, Lewis, Cathryn M, Lichtenstein, Paul, Svensson, Anna C

“…It is unknown how genetic variants conferring liability to psychiatric disorders survive in the population despite strong negative selection. However, this is…”
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Brain surface anatomy in adults with autism: the relationship between surface area, cortical thickness, and autistic symptoms by Ecker, Christine, Ginestet, Cedric, Feng, Yue, Johnston, Patrick, Lombardo, Michael V, Lai, Meng-Chuan, Suckling, John, Palaniyappan, Lena, Daly, Eileen, Murphy, Clodagh M, Williams, Steven C, Bullmore, Edward T, Baron-Cohen, Simon, Brammer, Michael, Murphy, Declan G M

“…Neuroimaging studies of brain anatomy in autism spectrum disorder (ASD) have mostly been based on measures of cortical volume (CV). However, CV is a product of…”
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Predicting treatment response in social anxiety disorder from functional magnetic resonance imaging by Doehrmann, Oliver, Ghosh, Satrajit S, Polli, Frida E, Reynolds, Gretchen O, Horn, Franziska, Keshavan, Anisha, Triantafyllou, Christina, Saygin, Zeynep M, Whitfield-Gabrieli, Susan, Hofmann, Stefan G, Pollack, Mark, Gabrieli, John D

“…Current behavioral measures poorly predict treatment outcome in social anxiety disorder (SAD). To our knowledge, this is the first study to examine…”
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Epidemiology of Autism Spectrum Disorders in Adults in the Community in England by Brugha, Traolach S, McManus, Sally, Bankart, John, Scott, Fiona, Purdon, Susan, Smith, Jane, Bebbington, Paul, Jenkins, Rachel, Meltzer, Howard

“…CONTEXT To our knowledge, there is no published information on the epidemiology of autism spectrum disorders (ASDs) in adults. If the prevalence of autism is…”
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A prospective study of autistic-like traits in unaffected siblings of probands with autism spectrum disorder by Georgiades, Stelios, Szatmari, Peter, Zwaigenbaum, Lonnie, Bryson, Susan, Brian, Jessica, Roberts, Wendy, Smith, Isabel, Vaillancourt, Tracy, Roncadin, Caroline, Garon, Nancy

“…The presence of autistic-like traits in relatives of individuals with autism spectrum disorder (ASD) is well recognized, but, to our knowledge, the emergence…”
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Mapping Common Psychiatric Disorders: Structure and Predictive Validity in the National Epidemiologic Survey on Alcohol and Related Conditions by Blanco, Carlos, Krueger, Robert F, Hasin, Deborah S, Liu, Shang-Min, Wang, Shuai, Kerridge, Bradley T, Saha, Tulshi, Olfson, Mark

“…CONTEXT Clinical experience and factor analytic studies suggest that some psychiatric disorders may be more closely related to one another, as indicated by the…”
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Predicting Psychosis: Meta-analysis of Transition Outcomes in Individuals at High Clinical Risk by Fusar-Poli, Paolo, Bonoldi, Ilaria, Yung, Alison R, Borgwardt, Stefan, Kempton, Matthew J, Valmaggia, Lucia, Barale, Francesco, Caverzasi, Edgardo, McGuire, Philip

“…CONTEXT A substantial proportion of people at clinical high risk of psychosis will develop a psychotic disorder over time. However, the risk of transition to…”
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Thalamocortical disconnection in the orbitofrontal region associated with cortical thinning in schizophrenia by Kubota, Manabu, Miyata, Jun, Sasamoto, Akihiko, Sugihara, Genichi, Yoshida, Hidefumi, Kawada, Ryosaku, Fujimoto, Shinsuke, Tanaka, Yusuke, Sawamoto, Nobukatsu, Fukuyama, Hidenao, Takahashi, Hidehiko, Murai, Toshiya

“…Dysfunction of the thalamocortical pathway has been proposed as a putative underlying pathology of schizophrenia. Although the mechanisms involved remain…”
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Genetic Heritability and Shared Environmental Factors Among Twin Pairs With Autism by Hallmayer, Joachim, Cleveland, Sue, Torres, Andrea, Phillips, Jennifer, Cohen, Brianne, Torigoe, Tiffany, Miller, Janet, Fedele, Angie, Collins, Jack, Smith, Karen, Lotspeich, Linda, Croen, Lisa A, Ozonoff, Sally, Lajonchere, Clara, Grether, Judith K, Risch, Neil

“…CONTEXT Autism is considered the most heritable of neurodevelopmental disorders, mainly because of the large difference in concordance rates between…”
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Mortality Rates in Patients With Anorexia Nervosa and Other Eating Disorders: A Meta-analysis of 36 Studies by Arcelus, Jon, Mitchell, Alex J, Wales, Jackie, Nielsen, Søren

“…CONTEXT: Morbidity and mortality rates in patients with eating disorders are thought to be high, but exact rates remain to be clarified. OBJECTIVE: To…”
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Fluoxetine, comprehensive cognitive behavioral therapy, and placebo in generalized social phobia by DAVIDSON, Jonathan R. T, FOA, Edna B, HUPPERT, Jonathan D, KEEFE, Francis J, FRANKLIN, Martin E, COMPTON, Jill S, NING ZHAO, CONNOR, Kathryn M, LYNCH, Thomas R, GADDE, Kishore M

“…Generalized social phobia is common, persistent, and disabling and is often treated with selective serotonin reuptake inhibitor drugs or cognitive behavioral…”
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Prevalence and Correlates of Bipolar Spectrum Disorder in the World Mental Health Survey Initiative by Merikangas, Kathleen R, Jin, Robert, He, Jian-Ping, Kessler, Ronald C, Lee, Sing, Sampson, Nancy A, Viana, Maria Carmen, Andrade, Laura Helena, Hu, Chiyi, Karam, Elie G, Ladea, Maria, Medina-Mora, Maria Elena, Ono, Yutaka, Posada-Villa, Jose, Sagar, Rajesh, Wells, J. Elisabeth, Zarkov, Zahari

“…CONTEXT There is limited information on the prevalence and correlates of bipolar spectrum disorder in international population-based studies using common…”
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Childhood Adversities and First Onset of Psychiatric Disorders in a National Sample of US Adolescents by McLaughlin, Katie A, Greif Green, Jennifer, Gruber, Michael J, Sampson, Nancy A, Zaslavsky, Alan M, Kessler, Ronald C

“…CONTEXT Although childhood adversities (CAs) are known to be highly co-occurring, most research examines their associations with psychiatric disorders one at a…”
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Prevalence, Persistence, and Sociodemographic Correlates of DSM-IV Disorders in the National Comorbidity Survey Replication Adolescent Supplement by Kessler, Ronald C, Avenevoli, Shelli, Costello, E. Jane, Georgiades, Katholiki, Green, Jennifer Greif, Gruber, Michael J, He, Jian-ping, Koretz, Doreen, McLaughlin, Katie A, Petukhova, Maria, Sampson, Nancy A, Zaslavsky, Alan M, Merikangas, Kathleen Ries

“…CONTEXT Community epidemiological data on the prevalence and correlates of adolescent mental disorders are needed for policy planning purposes. Only limited…”
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The nature of dopamine dysfunction in schizophrenia and what this means for treatment by Howes, Oliver D, Kambeitz, Joseph, Kim, Euitae, Stahl, Daniel, Slifstein, Mark, Abi-Dargham, Anissa, Kapur, Shitij

“…Current drug treatments for schizophrenia are inadequate for many patients, and despite 5 decades of drug discovery, all of the treatments rely on the same…”
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Prevalence and Correlates of Eating Disorders in Adolescents: Results From the National Comorbidity Survey Replication Adolescent Supplement by Swanson, Sonja A, Crow, Scott J, Le Grange, Daniel, Swendsen, Joel, Merikangas, Kathleen R

“…CONTEXT: Eating disorders are severe conditions, but little is known about the prevalence or correlates of these disorders from population-based surveys of…”
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