Search Results - "Archibald, L."

Precision engineering for PRRSV resistance in pigs: Macrophages from genome edited pigs lacking CD163 SRCR5 domain are fully resistant to both PRRSV genotypes while maintaining biological function by Burkard, Christine, Lillico, Simon G, Reid, Elizabeth, Jackson, Ben, Mileham, Alan J, Ait-Ali, Tahar, Whitelaw, C Bruce A, Archibald, Alan L

“…Porcine Reproductive and Respiratory Syndrome (PRRS) is a panzootic infectious disease of pigs, causing major economic losses to the world-wide pig industry…”
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ARGOS8 variants generated by CRISPR‐Cas9 improve maize grain yield under field drought stress conditions by Shi, Jinrui, Gao, Huirong, Wang, Hongyu, Lafitte, H. Renee, Archibald, Rayeann L., Yang, Meizhu, Hakimi, Salim M., Mo, Hua, Habben, Jeffrey E.

“…Summary Maize ARGOS8 is a negative regulator of ethylene responses. A previous study has shown that transgenic plants constitutively overexpressing ARGOS8 have…”
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Strong signatures of selection in the domestic pig genome by Rubin, Carl-Johan, Megens, Hendrik-Jan, Barrio, Alvaro Martinez, Maqbool, Khurram, Sayyab, Shumaila, Schwochow, Doreen, Wang, Chao, Carlborg, Örjan, Jern, Patric, Jørgensen, Claus B, Archibald, Alan L, Fredholm, Merete, Groenen, Martien A. M, Andersson, Leif

“…Domestication of wild boar (Sus scrofa) and subsequent selection have resulted in dramatic phenotypic changes in domestic pigs for a number of traits,…”
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Illuminating the dark side of the human transcriptome with long read transcript sequencing by Kuo, Richard I, Cheng, Yuanyuan, Zhang, Runxuan, Brown, John W S, Smith, Jacqueline, Archibald, Alan L, Burt, David W

“…The human transcriptome annotation is regarded as one of the most complete of any eukaryotic species. However, limitations in sequencing technologies have…”
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Livestock 2.0 - genome editing for fitter, healthier, and more productive farmed animals by Tait-Burkard, Christine, Doeschl-Wilson, Andrea, McGrew, Mike J, Archibald, Alan L, Sang, Helen M, Houston, Ross D, Whitelaw, C Bruce, Watson, Mick

“…The human population is growing, and as a result we need to produce more food whilst reducing the impact of farming on the environment. Selective breeding and…”
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Normalized long read RNA sequencing in chicken reveals transcriptome complexity similar to human by Kuo, Richard I, Tseng, Elizabeth, Eory, Lel, Paton, Ian R, Archibald, Alan L, Burt, David W

“…Despite the significance of chicken as a model organism, our understanding of the chicken transcriptome is limited compared to human. This issue is common to…”
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A chromosome-level genome assembly for the Pacific oyster Crassostrea gigas by Peñaloza, Carolina, Gutierrez, Alejandro P, Eöry, Lél, Wang, Shan, Guo, Ximing, Archibald, Alan L, Bean, Tim P, Houston, Ross D

“…Abstract Background The Pacific oyster (Crassostrea gigas) is a bivalve mollusc with vital roles in coastal ecosystems and aquaculture globally. While…”
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A high resolution atlas of gene expression in the domestic sheep (Ovis aries) by Clark, Emily L, Bush, Stephen J, McCulloch, Mary E B, Farquhar, Iseabail L, Young, Rachel, Lefevre, Lucas, Pridans, Clare, Tsang, Hiu G, Wu, Chunlei, Afrasiabi, Cyrus, Watson, Mick, Whitelaw, C Bruce, Freeman, Tom C, Summers, Kim M, Archibald, Alan L, Hume, David A

“…Sheep are a key source of meat, milk and fibre for the global livestock sector, and an important biomedical model. Global analysis of gene expression across…”
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International survey on growth indices and impacting factors in children with food allergies by Meyer, R., Wright, K., Vieira, M. C., Chong, K. W., Chatchatee, P., Vlieg‐Boerstra, B. J., Groetch, M., Dominguez‐Ortega, G., Heath, S., Lang, A., Archibald‐Durham, L., Rao, R., De Boer, R., Assa'ad, A., Trewella, E., Venter, C.

“…Background Elimination diets required for the management of food allergies increase the risk for poor growth in children. Currently, no worldwide data exist on…”
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Whole genome analysis of water buffalo and global cattle breeds highlights convergent signatures of domestication by Dutta, Prasun, Talenti, Andrea, Young, Rachel, Jayaraman, Siddharth, Callaby, Rebecca, Jadhav, Santosh Kumar, Dhanikachalam, Velu, Manikandan, Mayakannan, Biswa, Bhim B., Low, Wai Y., Williams, John L., Cook, Elizabeth, Toye, Phil, Wall, Eileen, Djikeng, Appolinaire, Marshall, Karen, Archibald, Alan L., Gokhale, Suresh, Kumar, Satish, Hume, David A., Prendergast, James G. D.

“…More people globally depend on the water buffalo than any other domesticated species, and as the most closely related domesticated species to cattle they can…”
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A high density recombination map of the pig reveals a correlation between sex-specific recombination and GC content by Tortereau, Flavie, Servin, Bertrand, Frantz, Laurent, Megens, Hendrik-Jan, Milan, Denis, Rohrer, Gary, Wiedmann, Ralph, Beever, Jonathan, Archibald, Alan L, Schook, Lawrence B, Groenen, Martien A M

“…The availability of a high-density SNP genotyping chip and a reference genome sequence of the pig (Sus scrofa) enabled the construction of a high-density…”
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A regulatory mutation in IGF2 causes a major QTL effect on muscle growth in the pig by Georges, Michel, Andersson, Leif, Van Laere, Anne-Sophie, Nguyen, Minh, Braunschweig, Martin, Nezer, Carine, Collette, Catherine, Moreau, Laurence, Archibald, Alan L, Haley, Chris S, Buys, Nadine, Tally, Michael, Andersson, Göran

“…Most traits and disorders have a multifactorial background indicating that they are controlled by environmental factors as well as an unknown number of…”
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Signatures of diversifying selection in European pig breeds by Wilkinson, Samantha, Lu, Zen H, Megens, Hendrik-Jan, Archibald, Alan L, Haley, Chris, Jackson, Ian J, Groenen, Martien A M, Crooijmans, Richard P M A, Ogden, Rob, Wiener, Pamela

“…Following domestication, livestock breeds have experienced intense selection pressures for the development of desirable traits. This has resulted in a large…”
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NET Rounding: a novel approach to efficient and effective rounds for the modern clinical learning environment by Chan, Shirley J., Archibald, Hannah L., Conner, Stephanie M.

“…Abstract Background Rounds are a foundational practice in patient care and education in the inpatient healthcare environment, but increased demands on…”
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Lawsonia intracellularis exploits β-catenin/Wnt and Notch signalling pathways during infection of intestinal crypt to alter cell homeostasis and promote cell proliferation by Huan, Yang W, Bengtsson, Rebecca J, MacIntyre, Neil, Guthrie, Jack, Finlayson, Heather, Smith, Sionagh H, Archibald, Alan L, Ait-Ali, Tahar

“…Lawsonia intracellularis is an obligate intracellular bacterial pathogen that causes proliferative enteropathy (PE) in pigs. L. intracellularis infection…”
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Comparative analysis of monocyte subsets in the pig by Fairbairn, Lynsey, Kapetanovic, Ronan, Beraldi, Dario, Sester, David P, Tuggle, Chris K, Archibald, Alan L, Hume, David A

“…Human and mouse monocyte can be divided into two different subpopulations based on surface marker expression: CD14/16 and Ly6C/CX3CR1, respectively. Monocyte…”
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Effects of age on tissues and regions of the cerebrum and cerebellum by Jernigan, Terry L., Archibald, Sarah L., Fennema-Notestine, Christine, Gamst, Anthony C., Stout, Julie C., Bonner, Julie, Hesselink, John R.

“…Normal volunteers, aged 30 to 99 years, were studied with MRI. Age was related to estimated volumes of: gray matter, white matter, and CSF of the cerebrum and…”
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Identifying Children with Persistent Developmental Dyscalculia from a 2‐min Test of Symbolic and Nonsymbolic Numerical Magnitude Processing by Bugden, S., Peters, L., Nosworthy, N., Archibald, L., Ansari, D.

“…ABSTRACT Developmental dyscalculia (DD) is a mathematical learning disability that occurs in around 5%–7% of the population. At present, there are only a…”
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Balancing selection at a premature stop mutation in the myostatin gene underlies a recessive leg weakness syndrome in pigs by Matika, Oswald, Robledo, Diego, Pong-Wong, Ricardo, Bishop, Stephen C, Riggio, Valentina, Finlayson, Heather, Lowe, Natalie R, Hoste, Annabelle E, Walling, Grant A, Del-Pozo, Jorge, Archibald, Alan L, Woolliams, John A, Houston, Ross D

“…Balancing selection provides a plausible explanation for the maintenance of deleterious alleles at moderate frequency in livestock, including lethal recessives…”
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sheep genome reference sequence: a work in progress by Archibald, A.L, Cockett, N.E, Dalrymple, B.P, Faraut, T, Kijas, J.W, Maddox, J.F, McEwan, J.C, Hutton Oddy, V, Raadsma, H.W, Wade, C, Wang, J, Wang, W, Xun, X

“…Until recently, the construction of a reference genome was performed using Sanger sequencing alone. The emergence of next-generation sequencing platforms now…”
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