Search Results - "Archer, John S."
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Cortex leads the thalamic centromedian nucleus in generalized epileptic discharges in Lennox‐Gastaut syndrome
Published in Epilepsia (Copenhagen) (01-10-2020)“…Summary Objective We aimed to assess the roles of the cortex and thalamus (centromedian nucleus [CM]) during epileptic activity in Lennox‐Gastaut syndrome…”
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Thalamocortical functional connectivity in Lennox–Gastaut syndrome is abnormally enhanced in executive‐control and default‐mode networks
Published in Epilepsia (Copenhagen) (01-12-2017)“…Summary Objective To identify abnormal thalamocortical circuits in the severe epilepsy of Lennox–Gastaut syndrome (LGS) that may explain the shared…”
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Lennox‐Gastaut syndrome and phenotype: Secondary network epilepsies
Published in Epilepsia (Copenhagen) (01-08-2014)“…Summary Objective Lennox‐Gastaut syndrome (LGS) is a severe epilepsy phenotype with characteristic electroclinical features despite diverse etiologies. We…”
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Hemiconvulsion-hemiplegia-epilepsy evolving to contralateral hemi-Lennox-Gastaut-like phenotype
Published in Brain & development (Tokyo. 1979) (01-05-2018)“…Hemiconvulsion-hemiplegia-epilepsy (HHE) involves infantile-onset acute hemiconvulsive febrile status epilepticus with subsequent unilateral cerebral atrophy…”
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Conceptualizing lennox-gastaut syndrome as a secondary network epilepsy
Published in Frontiers in neurology (01-01-2014)“…Lennox-Gastaut Syndrome (LGS) is a category of severe, disabling epilepsy, characterized by frequent, treatment-resistant seizures, and cognitive impairment…”
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Neuropsychological and functional MRI studies provide converging evidence of anterior language dysfunction in BECTS
Published in Epilepsia (Copenhagen) (01-10-2009)“…Summary Purpose: Benign childhood epilepsy with centrotemporal spikes (BECTS) is the most common epilepsy syndrome of childhood and can be associated with…”
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Small temporal pole encephaloceles: A treatable cause of “lesion negative” temporal lobe epilepsy
Published in Epilepsia (Copenhagen) (01-10-2010)“…Summary Epilepsy due to encephaloceles of the temporal pole may be an under recognized, treatable cause of refractory temporal lobe epilepsy (TLE). We describe…”
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Editorial: Functional Brain Mapping of Epilepsy Networks: Methods and Applications
Published in Frontiers in neuroscience (21-05-2019)“…With technology such as simultaneous electroencephalography and functional magnetic resonance imaging (EEG-fMRI) now more readily available, it is possible to…”
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DBS of Thalamic Centromedian Nucleus for Lennox–Gastaut Syndrome (ESTEL Trial)
Published in Annals of neurology (01-02-2022)“…Objective Prior uncontrolled studies have reported seizure reductions following deep brain stimulation (DBS) in patients with Lennox–Gastaut syndrome (LGS),…”
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Functional MRI interactions between dysplastic nodules and overlying cortex in periventricular nodular heterotopia
Published in Epilepsy & behavior (01-12-2010)“…Abstract Periventricular nodular heterotopia (PVNH) is a malformation of cortical development associated with epilepsy. It is unclear whether the epileptogenic…”
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Benign Epilepsy with Centro‐temporal Spikes: Spike Triggered fMRI Shows Somato‐sensory Cortex Activity
Published in Epilepsia (Copenhagen) (01-02-2003)“…Objective: We performed spike triggered functional MRI (fMRI) in a 12 year old girl with Benign Epilepsy with Centro‐temporal Spikes (BECTS) and left‐sided…”
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Epileptic encephalopathy: Use and misuse of a clinically and conceptually important concept
Published in Epilepsia (Copenhagen) (01-03-2016)“…Summary The term epileptic encephalopathy (EE) denotes a process by which epileptic activity adversely affects brain function over and above the underlying…”
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The epileptic network of Lennox-Gastaut syndrome: Cortically driven and reproducible across age
Published in Neurology (16-07-2019)“…OBJECTIVETo identify brain regions underlying interictal generalized paroxysmal fast activity (GPFA), and their causal interactions, in children and adults…”
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The Optimal Target and Connectivity for Deep Brain Stimulation in Lennox–Gastaut Syndrome
Published in Annals of neurology (01-07-2022)“…Objective Deep brain stimulation (DBS) can reduce seizures in Lennox–Gastaut syndrome (LGS). However, little is known about the optimal target and whether…”
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Targeted therapeutic mild hypercapnia after cardiac arrest: A phase II multi-centre randomised controlled trial (the CCC trial)
Published in Resuscitation (01-07-2016)“…Abstract Background In intensive care observational studies, hypercapnia after cardiac arrest (CA) is independently associated with improved neurological…”
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Paroxysmal fast activity is a biomarker of treatment response in deep brain stimulation for Lennox–Gastaut syndrome
Published in Epilepsia (Copenhagen) (01-12-2022)“…Objective Epilepsy treatment trials typically rely on seizure diaries to determine seizure frequency, but these are time‐consuming and difficult to maintain…”
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Frontoparietal 18F-FDG-PET hypo-metabolism in Lennox-Gastaut syndrome: Further evidence highlighting the key network
Published in Epilepsy research (01-05-2023)“…Lennox Gastaut syndrome (LGS) can be conceptualised as a “secondary network epilepsy”, in which the shared electroclinical manifestations reflect epileptic…”
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Cognition, adaptive skills and epilepsy disability/severity in patients with Lennox–Gastaut syndrome undergoing deep brain stimulation for epilepsy in the ESTEL trial
Published in Seizure (London, England) (01-10-2022)“…•Cognitive and behavioral testing in patients with Lennox–Gastaut syndrome (LGS) can be challenging.•As part of the ESTEL trial (thalamic DBS in LGS), we…”
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A Sheep Model for the Study of Focal Epilepsy with Concurrent Intracranial EEG and Functional MRI
Published in Epilepsia (Copenhagen) (01-08-2002)“…Purpose: We describe a sheep model of penicillin‐induced seizure activity using electroencephalography (EEG) and functional MRI (fMRI). Methods: Ten adult…”
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Response: Can ECT cause “kindling” in the human brain ?
Published in Epilepsia (Copenhagen) (01-01-2017)Get full text
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