Sampling and analysis techniques for monitoring serum for trace elements

We describe techniques for controlling contamination in the sampling and analysis of human serum for trace metals. The relatively simple procedures do not require clean-room conditions. The atomic absorption and atomic emission methods used have been applied in studying zinc, copper, chromium, manga...

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Bibliographic Details
Published in:	Clinical chemistry (Baltimore, Md.) Vol. 32; no. 7; p. 1350
Main Authors:	Ericson, S P, McHalsky, M L, Rabinow, B E, Kronholm, K G, Arceo, C S, Weltzer, J A, Ayd, S W
Format:	Journal Article
Language:	English
Published:	England 01-07-1986
Subjects:	Blood Specimen Collection Female Humans Male Reference Values Specimen Handling Spectrophotometry, Atomic - methods Statistics as Topic Trace Elements - blood Trace Elements - standards
Online Access:	Get more information
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Summary:	We describe techniques for controlling contamination in the sampling and analysis of human serum for trace metals. The relatively simple procedures do not require clean-room conditions. The atomic absorption and atomic emission methods used have been applied in studying zinc, copper, chromium, manganese, molybdenum, selenium, and aluminum concentrations. Values obtained for a group of 16 normal subjects agree with the most reliable values reported in the literature, obtained by much more elaborate techniques. All of these metals can be measured in 3 to 4 mL of serum. The methods may prove especially useful in monitoring concentrations of essential trace elements in blood of patients being maintained on total parenteral nutrition.
ISSN:	0009-9147
DOI:	10.1093/clinchem/32.7.1350