Search Results - "Arcangeli, Tania"
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The Interplay of Reactive Oxygen Species, Hypoxia, Inflammation, and Sirtuins in Cancer Initiation and Progression
Published in Oxidative medicine and cellular longevity (01-01-2016)“…The presence of ROS is a constant feature in living cells metabolizing O2. ROS concentration and compartmentation determine their physiological or pathological…”
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SIRT5 regulation of ammonia-induced autophagy and mitophagy
Published in Autophagy (01-02-2015)“…In liver the mitochondrial sirtuin, SIRT5, controls ammonia detoxification by regulating CPS1, the first enzyme of the urea cycle. However, while SIRT5 is…”
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Pharmacological Activation of SIRT3 Modulates the Response of Cancer Cells to Acidic pH
Published in Pharmaceuticals (Basel, Switzerland) (20-06-2024)“…Cancer cells modulate their metabolism, creating an acidic microenvironment that, in turn, can favor tumor progression and chemotherapy resistance. Tumor cells…”
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Simulative and experimental investigation on the cleavage site that generates the soluble human LOX-1
Published in Archives of biochemistry and biophysics (01-12-2013)“…[Display omitted] •LOX-1 is a scavenger receptor that binds and internalizes ox-LDL.•A circulating soluble LOX-1 form has been associated to acute coronary…”
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