Search Results - "Arboleas, Mélanie"

Glycosaminoglycans exhibit distinct interactions and signaling with BMP2 according to their nature and localization by Le Pennec, Jean, Makshakova, Olga, Nevola, Paola, Fouladkar, Farah, Gout, Evelyne, Machillot, Paul, Friedel-Arboleas, Mélanie, Picart, Catherine, Perez, Serge, Vortkamp, Andrea, Vivès, Romain R., Migliorini, Elisa

“…The role of glycosaminoglycans (GAGs) in modulating bone morphogenetic protein (BMP) signaling represents a recent and underexplored area. Conflicting reports…”
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Tumor suppressive role of the antimicrobial lectin REG3A targeting the O -GlcNAc glycosylation pathway by Moniaux, Nicolas, Geoffre, Nicolas, Deshayes, Alice, Dos Santos, Alexandre, Job, Sylvie, Lacoste, Claire, Nguyen, Tung-Son, Darnaud, Marion, Friedel-Arboleas, Mélanie, Guettier, Catherine, Purhonen, Janne, Kallijärvi, Jukka, Amouyal, Gilles, Amouyal, Paul, Bréchot, Christian, Vivès, Romain R, Buendia, Marie Annick, Issad, Tarik, Faivre, Jamila

“…Antimicrobial proteins of the regenerating family member 3 alpha (REG3A) family provide a first line of protection against infections and transformed cells…”
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Extracellular endosulfatase Sulf-2 harbors a chondroitin/dermatan sulfate chain that modulates its enzyme activity by El Masri, Rana, Seffouh, Amal, Roelants, Caroline, Seffouh, Ilham, Gout, Evelyne, Pérard, Julien, Dalonneau, Fabien, Nishitsuji, Kazuchika, Noborn, Fredrik, Nikpour, Mahnaz, Larson, Göran, Crétinon, Yoann, Friedel-Arboleas, Mélanie, Uchimura, Kenji, Daniel, Régis, Lortat-Jacob, Hugues, Filhol, Odile, Vivès, Romain R.

“…Sulfs represent a class of unconventional sulfatases which provide an original post-synthetic regulatory mechanism for heparan sulfate polysaccharides and are…”
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Phenyltetrahydroisoquinoline–Pyridinaldoxime Conjugates as Efficient Uncharged Reactivators for the Dephosphylation of Inhibited Human Acetylcholinesterase by Mercey, Guillaume, Renou, Julien, Verdelet, Tristan, Kliachyna, Maria, Baati, Rachid, Gillon, Emilie, Arboléas, Mélanie, Loiodice, Mélanie, Nachon, Florian, Jean, Ludovic, Renard, Pierre-Yves

“…Pyridinium and bis-pyridinium aldoximes are used as antidotes to reactivate acetylcholinesterase (AChE) inhibited by organophosphorus nerve agents. Herein, we…”
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Targeting CD44 receptor-positive lung tumors using polysaccharide-based nanocarriers: Influence of nanoparticle size and administration route by Jeannot, Victor, PharmD, Mazzaferro, Silvia, PharmD, PhD, Lavaud, Jonathan, Vanwonterghem, Laetitia, Henry, Maxime, Arboléas, Mélanie, Vollaire, Julien, Josserand, Véronique, PhD, Coll, Jean-Luc, PhD, Lecommandoux, Sébastien, PhD, Schatz, Christophe, PhD, Hurbin, Amandine, PhD

“…Abstract New approaches that are more efficient and able to specifically reach lung tumors are needed. We developed new hyaluronan-based nanoparticles…”
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Design, synthesis and biological evaluation of novel tetrahydroacridine pyridine- aldoxime and -amidoxime hybrids as efficient uncharged reactivators of nerve agent-inhibited human acetylcholinesterase by Kliachyna, Maria, Santoni, Gianluca, Nussbaum, Valentin, Renou, Julien, Sanson, Benoit, Colletier, Jacques-Philippe, Arboléas, Mélanie, Loiodice, Mélanie, Weik, Martin, Jean, Ludovic, Renard, Pierre-Yves, Nachon, Florian, Baati, Rachid

“…A series of new uncharged functional acetylcholinesterase (AChE) reactivators including heterodimers of tetrahydroacridine with 3-hydroxy-2-pyridine aldoximes…”
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Tryptoline-3-hydroxypyridinaldoxime conjugates as efficient reactivators of phosphylated human acetyl and butyrylcholinesterases by Renou, Julien, Loiodice, Mélanie, Arboléas, Mélanie, Baati, Rachid, Jean, Ludovic, Nachon, Florian, Renard, Pierre-Yves

“…Two promising uncharged reactivators for inhibited human BChE and AChE have been described. These compounds show an ability to reactivate VX-inhibited BChE…”
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Syntheses and in vitro evaluations of uncharged reactivators for human acetylcholinesterase inhibited by organophosphorus nerve agents by Renou, Julien, Mercey, Guillaume, Verdelet, Tristan, Păunescu, Emilia, Gillon, Emilie, Arboléas, Mélanie, Loiodice, Mélanie, Kliachyna, Maria, Baati, Rachid, Nachon, Florian, Jean, Ludovic, Renard, Pierre-Yves

“…[Display omitted] ► Syntheses of a series of uncharged AChE reactivators. ► All compounds are superior to 2-PAM for the reactivation of VX-inhibited hAChE. ►…”
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Hereditary angioedema: Key role for kallikrein and bradykinin in vascular endothelial-cadherin cleavage and edema formation by Bouillet, Laurence, Mannic, Tiphaine, Arboleas, Mélanie, Subileau, Mariela, Massot, Christian, Drouet, Christian, Huber, Philippe, Vilgrain, Isabelle

“…To the Editor: Hereditary angioedema (HAE) is characterized by recurrent episodes of edema that can be life-threatening if not treated properly.1 It is an…”
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An easy method for the determination of active concentrations of cholinesterase reactivators in blood samples: Application to the efficacy assessment of non quaternary reactivators compared to HI-6 and pralidoxime in VX-poisoned mice by Calas, André-Guilhem, Dias, José, Rousseau, Catherine, Arboléas, Mélanie, Touvrey-Loiodice, Mélanie, Mercey, Guillaume, Jean, Ludovic, Renard, Pierre-Yves, Nachon, Florian

“…Organophosphorus nerve agents, like VX, are highly toxic due to their strong inhibition potency against acetylcholinesterase (AChE). AChE inhibited by VX can…”
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Interplay between integrins and cadherins to control bone differentiation upon BMP-2 stimulation by Valat, Anne, Fourel, Laure, Sales, Adria, Machillot, Paul, Bouin, Anne-Pascale, Fournier, Carole, Bosc, Lauriane, Arboléas, Mélanie, Bourrin-Reynard, Ingrid, Wagoner Johnson, Amy J, Bruckert, Franz, Albigès-Rizo, Corinne, Picart, Catherine

“…Upon BMP-2 stimulation, the osteoblastic lineage commitment in C2C12 myoblasts is associated with a microenvironmental change that occurs over several days…”
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Evidence for post-translational processing of vascular endothelial (VE)-cadherin in brain tumors: towards a candidate biomarker by Vilgrain, Isabelle, Sidibé, Adama, Polena, Helena, Cand, Francine, Mannic, Tiphaine, Arboleas, Mélanie, Boccard, Sandra, Baudet, Antoine, Gulino-Debrac, Danielle, Bouillet, Laurence, Quesada, Jean-Louis, Mendoza, Christophe, Lebas, Jean-François, Pelletier, Laurent, Berger, François

“…Vessel abnormalities are among the most important features in malignant glioma. Vascular endothelial (VE)-cadherin is of major importance for vascular…”
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Hereditary angioedema: Key role for kallikrein and bradykinin in vascular endothelialcadherin cleavage and edema formation by BOUILLET, Laurence, MANNIC, Tiphaine, ARBOLEAS, Mélanie, SUBILEAU, Mariela, MASSOT, Christian, DROUET, Christian, HUBER, Philippe, VILGRAIN, Isabelle

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Soluble VE-cadherin in rheumatoid arthritis patients correlates with disease activity: Evidence for tumor necrosis factor [alpha]-induced VE-cadherin cleavage by Sidibe, Adama, Mannic, Tiphaine, Arboleas, Mélanie, Subileau, Mariela, Gulino-Debrac, Danielle, Bouillet, Laurence, Jan, Mary, Vandhuick, Thibault, Le Loet, Xavier, Vittecoq, Olivier, Vilgrain, Isabelle

“…Objective Rheumatoid arthritis (RA) is a chronic, systemic inflammatory disorder that principally attacks synovial joints. However, accelerated atherosclerosis…”
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Soluble VE-cadherin in rheumatoid arthritis patients correlates with disease activity: Evidence for tumor necrosis factor α-induced VE-cadherin cleavage by Sidibé, Adama, Mannic, Tiphaine, Arboleas, Mélanie, Subileau, Mariela, Gulino-Debrac, Danielle, Bouillet, Laurence, Jan, Mary, Vandhuick, Thibault, Le Loët, Xavier, Vittecoq, Olivier, Vilgrain, Isabelle

“…Objective Rheumatoid arthritis (RA) is a chronic, systemic inflammatory disorder that principally attacks synovial joints. However, accelerated atherosclerosis…”
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Hereditary angioedema: Key role for kallikrein and bradykinin in vascular endothelial-cadherin cleavage and edema formation by Bouillet, Laurence, MD, PhD, Mannic, Tiphaine, PhD, Arboleas, Mélanie, Subileau, Mariela, Massot, Christian, MD, Drouet, Christian, PhD, Huber, Philippe, PhD, Vilgrain, Isabelle, PhD

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