Search Results - "Aravind, SR"
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Remogliflozin Etabonate in the Treatment of Type 2 Diabetes: Design, Development, and Place in Therapy
Published in Drug design, development and therapy (01-01-2020)“…Type 2 diabetes mellitus (T2DM) is an emerging epidemic in Asian countries, especially in India. With the advent of the SGLT2 inhibitor class of drugs…”
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The role of p53-microRNA 200-Moesin axis in invasion and drug resistance of breast cancer cells
Published in Tumor biology (01-09-2017)“…This study aimed to analyze the expression of microRNAs in relation to p53 status in breast cancer cells and to delineate the role of Moesin in this axis. We…”
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Curcumin-albumin conjugates as an effective anti-cancer agent with immunomodulatory properties
Published in International immunopharmacology (01-05-2016)“…Curcumin (diferuloylmethane) is an active ingredient in turmeric (Curcuma longa) with anti-inflammatory, antioxidant, chemopreventive, chemosensitization, and…”
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A galactomannan polysaccharide from Punica granatum imparts in vitro and in vivo anticancer activity
Published in Carbohydrate polymers (06-11-2013)“…•Polysaccharide PSP001 is water soluble and biodegradable.•PSP001 was found to be non-toxic up to 2000mg/kg in BALB/c mice.•PSP001 was previously found to…”
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Immunostimulatory plant polysaccharides impede cancer progression and metastasis by avoiding off-target effects
Published in International immunopharmacology (01-08-2019)“…An unexploited homo-polysaccharide (PSM001) isolated from the seed kernel of Kottukonam variety of Mangifera indica, demonstrated selective cytotoxicity…”
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Galactoxyloglucan-modified nanocarriers of doxorubicin for improved tumor-targeted drug delivery with minimal toxicity
Published in Journal of biomedical nanotechnology (01-11-2014)“…Doxorubicin (Dox) is commonly used to treat human malignancies, and the efficacy of Dox can be maximized by limiting toxicity when combined with nanoparticles…”
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TRAIL-based tumor sensitizing galactoxyloglucan, a novel entity for targeting apoptotic machinery
Published in The international journal of biochemistry & cell biology (01-02-2015)“…•Morphological evaluation proved that PST001 induces apoptosis in cancer cells.•PST001-induced apoptosis was evidenced by the increase in Annexin V positive…”
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Antitumor activity of galactoxyloglucan-gold nanoparticles against murine ascites and solid carcinoma
Published in Colloids and surfaces, B, Biointerfaces (01-04-2014)“…Galactoxyloglucan polysaccharide (PST001), isolated from the seed kernels of Tamarindus indica (Ti), was used both as reducing and capping agent for the…”
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The INtegrating DEPrEssioN and Diabetes treatmENT (INDEPENDENT) study: Design and methods to address mental healthcare gaps in India
Published in Contemporary clinical trials (01-09-2017)“…Abstract Introduction Depression and diabetes are highly prevalent worldwide and often co-exist, worsening outcomes for each condition. Barriers to diagnosis…”
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Asarones from Acorus calamus in Combination with Azoles and Amphotericin B: A Novel Synergistic Combination to Compete Against Human Pathogenic Candida Species In Vitro
Published in Applied biochemistry and biotechnology (01-04-2015)“…The increase in drug resistance to current antifungal drugs brings enormous challenges to the management of Candida infection. Therefore, there is a continuous…”
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PO-001 Environmental toxins can transform mammary cells and induce chemo-resistance in breast cancer via multiple mechanisms
Published in ESMO open (01-06-2018)“…IntroductionThere is an ample epidemiological and in vivo evidence to support the role of environmental contaminants such as bisphenol A (BPA) in breast cancer…”
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RSSDI consensus recommendations on insulin therapy in the management of diabetes
Published in International journal of diabetes in developing countries (01-11-2019)“…The Research Society for the Study of Diabetes in India (RSSDI) has regularly updated its Clinical Practice Guidelines on various aspects of diabetes. The…”
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Real-World Observational Study of Glimepiride and Metformin Fixed-Dose Combination Along With Insulin in the Management of Type 2 Diabetes Mellitus: Indian Experience
Published in Curēus (Palo Alto, CA) (30-01-2021)“…Background Type 2 diabetes mellitus (T2DM) is associated with a significant burden on both patients and the healthcare system. This study aimed to evaluate the…”
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Strengthening the Family - the 'Five-I' Approach
Published in European endocrinology (01-04-2019)“…This article describes the importance of the family in diabetes care. It lists the multiple ways in which the family is related to diabetes: as a cause or…”
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Consensus Statement on Management of Post-Prandial Hyperglycemia in Clinical Practice in India
Published in Journal of the Association of Physicians of India (01-08-2015)“…Postprandial hyperglycemia (PPHG) is a detrimental factor in the evolution of diabetes related complications. Numerous studies have established the role of…”
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Diabetes and driving
Published in International journal of diabetes in developing countries (01-12-2017)“…More than 69 million Indians are suffering from diabetes, of which a substantial proportion of the population are currently holding or will seek in the future…”
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A Case of Jejunal Atresia Associated With Heterotrophic Pancreas and Meckel's Diverticulum
Published in Curēus (Palo Alto, CA) (21-12-2022)“…Apart from meconium ileus, amniotic fluid plug syndrome, malrotation of the gut, Hirschprung's disorder, trauma, and other rare causes, bowel atresia is one of…”
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