Search Results - "Arauzo"
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Vulnerability of groundwater resources to nitrate pollution: A simple and effective procedure for delimiting Nitrate Vulnerable Zones
Published in The Science of the total environment (01-01-2017)“…This research was undertaken to further our understanding of the factors involved in nonpoint-source nitrate pollution of groundwater. The shortcomings of some…”
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2
Cell-to-cell expression variability followed by signal reinforcement progressively segregates early mouse lineages
Published in Nature cell biology (01-01-2014)“…It is now recognized that extensive expression heterogeneities among cells precede the emergence of lineages in the early mammalian embryo. To establish a map…”
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3
Direct reprogramming of human neural stem cells by OCT4
Published in Nature (London) (01-10-2009)“…Induced pluripotent stem (iPS) cells have been generated from mouse and human somatic cells by ectopic expression of four transcription factors (OCT4 (also…”
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4
Direct Reprogramming of Hepatic Myofibroblasts into Hepatocytes In Vivo Attenuates Liver Fibrosis
Published in Cell stem cell (02-06-2016)“…Direct induction of induced hepatocytes (iHeps) from fibroblasts holds potential as a strategy for regenerative medicine but until now has only been shown in…”
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Direct Reprogramming of Fibroblasts into Neural Stem Cells by Defined Factors
Published in Cell stem cell (06-04-2012)“…Recent studies have shown that defined sets of transcription factors can directly reprogram differentiated somatic cells to a different differentiated cell…”
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6
Human primordial germ cell commitment in vitro associates with a unique PRDM14 expression profile
Published in The EMBO journal (15-04-2015)“…Primordial germ cells (PGCs) develop only into sperm and oocytes in vivo . The molecular mechanisms underlying human PGC specification are poorly understood…”
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Metabolic control of adult neural stem cell activity by Fasn-dependent lipogenesis
Published in Nature (London) (10-01-2013)“…Adult neural stem and progenitor cells (NSPCs) show high levels of fatty acid synthase (Fasn)-dependent de novo lipogenesis, a process that is controlled by…”
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RNA-sequencing from single nuclei
Published in Proceedings of the National Academy of Sciences - PNAS (03-12-2013)“…It has recently been established that synthesis of double-stranded cDNA can be done from a single cell for use in DNA sequencing. Global gene expression can be…”
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DNA methylation regulates discrimination of enhancers from promoters through a H3K4me1-H3K4me3 seesaw mechanism
Published in BMC genomics (12-12-2017)“…DNA methylation at promoters is largely correlated with inhibition of gene expression. However, the role of DNA methylation at enhancers is not fully…”
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Targeting liver sinusoidal endothelial cells with miR‐20a‐loaded nanoparticles reduces murine colon cancer metastasis to the liver
Published in International journal of cancer (01-08-2018)“…Phenotypic transformation of liver sinusoidal endothelial cells is one of the most important stages of liver metastasis progression. The miRNA effects on liver…”
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Direct Induction of Trophoblast Stem Cells from Murine Fibroblasts
Published in Cell stem cell (05-11-2015)“…Trophoblast stem cells (TSCs) arise from the first cell fate decision in the developing embryo and generate extra-embryonic lineages, giving rise to the fetal…”
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Skeletal Muscles of Sedentary and Physically Active Aged People Have Distinctive Genic Extrachromosomal Circular DNA Profiles
Published in International journal of molecular sciences (01-02-2023)“…To bring new extrachromosomal circular DNA (eccDNA) enrichment technologies closer to the clinic, specifically for screening, early diagnosis, and monitoring…”
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13
Oct4-Induced Pluripotency in Adult Neural Stem Cells
Published in Cell (06-02-2009)“…The four transcription factors Oct4, Sox2, Klf4, and c-Myc can induce pluripotency in mouse and human fibroblasts. We previously described direct reprogramming…”
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Oct4-induced oligodendrocyte progenitor cells enhance functional recovery in spinal cord injury model
Published in The EMBO journal (02-12-2015)“…The generation of patient‐specific oligodendrocyte progenitor cells (OPCs) holds great potential as an expandable cell source for cell replacement therapy as…”
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15
Backshoring and nearshoring: An overview
Published in Growth and change (01-09-2019)“…Increasingly, economies that have traditionally benefited from offshoring are losing some of their strategical advantages, with a consequent increase in…”
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Pluripotent stem cells induced from adult neural stem cells by reprogramming with two factors
Published in Nature (31-07-2008)“…Reprogramming of somatic cells is a valuable tool to understand the mechanisms of regaining pluripotency and further opens up the possibility of generating…”
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The key roles of renewable energy and economic growth in disaggregated environmental degradation: Evidence from highly developed, heterogeneous and cross-correlated countries
Published in Renewable energy (01-04-2023)“…This paper investigates the validity of the environmental Kuznets curve (EKC) hypothesis for the G7 group of countries through the ecological footprint and its…”
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18
Human Dermal Fibroblast Subpopulations Are Conserved across Single-Cell RNA Sequencing Studies
Published in Journal of investigative dermatology (01-07-2021)“…On the basis of their differential location within the dermis and of discrete changes in gene and protein expression, two major fibroblast subtypes (papillary…”
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Chromatin-Remodeling Components of the BAF Complex Facilitate Reprogramming
Published in Cell (11-06-2010)“…Reprogramming of somatic cells achieved by combination of the four transcription factors Oct4, Sox2, Klf4, and c-Myc has very low efficiency. To increase the…”
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20
FGF signalling inhibits neural induction in human embryonic stem cells
Published in The EMBO journal (14-12-2011)“…Human embryonic stem cells (hESCs) can exit the self‐renewal programme, through the action of signalling molecules, at any given time and differentiate along…”
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