Search Results - "Araujo Furlan, Cintia L"
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Interleukin-17 signaling influences CD8+ T cell immunity and tumor progression according to the IL-17 receptor subunit expression pattern in cancer cells
Published in Oncoimmunology (31-12-2023)“…IL-17 immune responses in cancer are controversial, with both tumor-promoting and tumor-repressing effects observed. To clarify the role of IL-17 signaling in…”
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CD39 Expression Defines Cell Exhaustion in Tumor-Infiltrating CD8 + T Cells
Published in Cancer research (Chicago, Ill.) (01-01-2018)“…The ability of CD8 T lymphocytes to eliminate tumors is limited by their ability to engender an immunosuppressive microenvironment. Here we describe a subset…”
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CD39 expression by regulatory T cells participates in CD8+ T cell suppression during experimental Trypanosoma cruzi infection
Published in PLoS pathogens (01-04-2024)“…An imbalance between suppressor and effector immune responses may preclude cure in chronic parasitic diseases. In the case of Trypanosoma cruzi infection,…”
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CD8 + T Cell Immunity Is Compromised by Anti-CD20 Treatment and Rescued by Interleukin-17A
Published in mBio (12-05-2020)“…Treatment with anti-CD20, used in many diseases in which B cells play a pathogenic role, has been associated with susceptibility to intracellular infections…”
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IL-17RA-Signaling Modulates CD8+ T Cell Survival and Exhaustion During Trypanosoma cruzi Infection
Published in Frontiers in immunology (11-10-2018)“…The IL-17 family contributes to host defense against many intracellular pathogens by mechanisms that are not fully understood. CD8+ T lymphocytes are key…”
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Limited Foxp3 + Regulatory T Cells Response During Acute Trypanosoma cruzi Infection Is Required to Allow the Emergence of Robust Parasite-Specific CD8 + T Cell Immunity
Published in Frontiers in immunology (05-11-2018)“…While it is now acknowledged that CD4 T cells expressing CD25 and Foxp3 (Treg cells) regulate immune responses and, consequently, influence the pathogenesis of…”
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Understanding CD8+ T Cell Immunity to Trypanosoma cruzi and How to Improve It
Published in Trends in parasitology (01-11-2019)“…The protozoan Trypanosoma cruzi is the causative agent of Chagas' disease, endemic in Latin America but present worldwide. Research efforts have focused on the…”
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Understanding CD8+ T cell immunity to T. cruzi and how to improve it
Published in Trends in parasitology (10-10-2019)“…The protozoan Trypanosoma cruzi is the causative agent of Chagas disease, endemic in Latin America but present worldwide. Research efforts have focused on the…”
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Journal Article