Search Results - "Araujo‐Santos, Théo"

Understanding the Mechanisms Controlling Leishmania amazonensis Infection In Vitro: The Role of LTB₄ Derived From Human Neutrophils by Tavares, Natalia Machado, Araújo-Santos, Théo, Afonso, Lilian, Nogueira, Paula Monalisa, Lopes, Ulisses Gazos, Soares, Rodrigo Pedro, Bozza, Patrícia Torres, Bandeira-Melo, Christianne, Borges, Valeria Matos, Brodskyn, Cláudia

“…Neutrophils are rapidly recruited to the site of Leishmania infection and play an active role in capturing and killing parasites. They are the main source of…”
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Inflammatory mediators in sickle cell anaemia highlight the difference between steady state and crisis in paediatric patients by Carvalho, Magda O. S., Araujo‐Santos, Théo, Reis, João H. O., Rocha, Larissa C., Cerqueira, Bruno A. V., Luz, Nívea F., Lyra, Isa M., Lopes, Valma M., Barbosa, Cynara G., Fiuza, Luciana M., Santiago, Rayra P., Figueiredo, Camylla V. B., Guarda, Caroline C., Barral Neto, Manoel, Borges, Valéria M., Gonçalves, Marilda S.

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Anti-parasite therapy drives changes in human visceral leishmaniasis-associated inflammatory balance by Araújo-Santos, Théo, Andrade, Bruno B., Gil-Santana, Leonardo, Luz, Nívea F., dos Santos, Priscila L., de Oliveira, Fabrícia A., Almeida, Meirielly Lima, de Santana Campos, Roseane Nunes, Bozza, Patrícia T., Almeida, Roque P., Borges, Valeria M.

“…Visceral leishmaniasis (VL) remains a major public health problem worldwide. Cytokine balance is thought to play a critical role in the development of this…”
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Lutzomyia longipalpis saliva drives apoptosis and enhances parasite burden in neutrophils by Prates, Deboraci Brito, Araújo‐Santos, Théo, Luz, Nívea Farias, Andrade, Bruno B., França‐Costa, Jaqueline, Afonso, Lilian, Clarêncio, Jorge, Miranda, José Carlos, Bozza, Patrícia T., DosReis, George A., Brodskyn, Cláudia, Barral‐Netto, Manoel, Borges, Valéria Matos, Barral, Aldina

“…Salivary proteins from Lutzomyia longipalpis induce host neutrophil caspase‐dependent apoptosis and infection by Leishmania chagasi. Neutrophils are considered…”
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Associations between TGF-β1 Levels and Markers of Hemolysis, Inflammation, and Tissue Remodeling in Pediatric Sickle Cell Patients by Santiago, Rayra P., Carvalho, Magda O. S., Figueiredo, Camylla V. B., Fiuza, Luciana M., Oliveira, Rodrigo M., Yahouédéhou, Sètondji C. M. A., Nascimento, Valma M. L., Lyra, Isa M., Araujo-Santos, Théo, Luz, Nívea F., Aleluia, Milena M., Guarda, Caroline C., Borges, Valéria M., Goncalves, Marilda S.

“…Transforming growth factor beta (TGF-β) is a cytokine with important involvement in biological processes related to the pathogenesis of sickle cell disease…”
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Activation Pathways of Murine Macrophages by Lipophosphoglycan from Strains of Leishmania major (FV1 and LV39) by Mançur Santos, Vanessa, Goicochea, Astrid Madeleine Calero, Soares Neto, Antônio José, Jesus Santos, Flávio Henrique, Lobo da Silva, Jéssica, Araújo-Santos, Théo, Paiva Farias, Leonardo, Brodskyn, Claudia Ida, M. Borges, Valéria, Pedro Soares, Rodrigo, Berlink Lima, Jonilson

“…Lipophosphoglycan (LPG) is an important Leishmania virulence factor. It is the most abundant surface glycoconjugate in promastigotes, playing an important role…”
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Lutzomyia longipalpis Saliva Drives Interleukin-17-Induced Neutrophil Recruitment Favoring Leishmania infantum Infection by Teixeira, Clarissa R, Santos, Claire da S, Prates, Deboraci B, Dos Santos, Rafael T, Araújo-Santos, Théo, de Souza-Neto, Sebastião M, Borges, Valéria M, Barral-Netto, Manoel, Brodskyn, Cláudia I

“…During bloodfeeding, the presence of sand fly saliva in the hemorrhagic pool where is also inoculated modulates the development of host immune mechanisms…”
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Lutzomyia longipalpis saliva triggers lipid body formation and prostaglandin E₂ production in murine macrophages by Araújo-Santos, Théo, Prates, Deboraci Brito, Andrade, Bruno Bezerril, Nascimento, Danielle Oliveira, Clarêncio, Jorge, Entringer, Petter F, Carneiro, Alan B, Silva-Neto, Mário A C, Miranda, José Carlos, Brodskyn, Cláudia Ida, Barral, Aldina, Bozza, Patrícia T, Borges, Valéria Matos

“…Sand fly saliva contains molecules that modify the host's hemostasis and immune responses. Nevertheless, the role played by this saliva in the induction of key…”
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COX-2 rs20417 Polymorphism Is Associated with Stroke and White Matter Disease by Oliveira-Filho, Jamary, MD, MS, PhD, Ornellas, Ana C.P., MS, PhD, Zhang, Cathy R., PhD, Oliveira, Luciana M.B., MD, PhD, Araújo-Santos, Théo, PhD, Borges, Valeria M., PhD, Ventura, Laís M.G.B., MD, Reis, Francisco J.F.B., MD, PhD, Aras, Roque, MD, PhD, Fernandes, André M., MD, Rosand, Jonathan, MD, PhD, Greenberg, Steven M., MD, PhD, Furie, Karen L., MD, MPH, Rost, Natalia S., MD, MPH

“…Background To investigate the effect of COX-2 polymorphism and its product, prostaglandin E2 (PGE2), on stroke risk in an endemic area for Chagas disease. In a…”
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Prostaglandin E2/Leukotriene B4 balance and viral load in distinct clinical stages of COVID-19: A cross-sectional study by Gadelha, Larisse Ricardo, Costa, Maria Juliana Bezerra, Abreu, João Paulo Alecrim de, Venancio, Larissa Paola Rodrigues, Fabres-Klein, Mary Hellen, Klein, Raphael Contelli, Lima, Jonilson Berlink, Araújo-Santos, Théo

“…Prostaglandin E2 (PGE2) and leukotriene B4 (LTB4) are eicosanoids involved in modulation of the antiviral immune response. Recent studies have identified…”
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New Insights on the Inflammatory Role of Lutzomyia longipalpis Saliva in Leishmaniasis by Prates, Deboraci Brito, Araújo-Santos, Théo, Brodskyn, Cláudia, Barral-Netto, Manoel, Barral, Aldina, Borges, Valéria Matos

“…When an haematophagous sand fly vector insect bites a vertebrate host, it introduces its mouthparts into the skin and lacerates blood vessels, forming a…”
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Identifying Inconclusive Data in the SARS-CoV-2 Molecular Diagnostic Using Nucleocapsid Phosphoprotein Gene as a Target by Klein, Raphael Contelli, Klein, Mary Hellen Fabres, Barbosa, Larissa Gomes, Gonzaga Knnup, Lívia Vasconcelos, Rodrigues Venâncio, Larissa Paola, Lima, Jonilson Berlink, Araújo-Santos, Théo

“…The gold standard test to identify the presence of SARS-CoV-2 in COVID-19 patients is the real-time reverse transcription-quantitative polymerase chain…”
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Coagulopathy and the humoral response against viral proteins in patients at different stages of COVID-19 by Monteiro, Fernanda Pereira, Tavares, Victor de Souza, Souza, Rayane da Silva Oliveira, Venâncio, Larissa Paola Rodrigues, Fabres-Klein, Mary Hellen, do Carmo, Rodrigo Feliciano, Klein, Raphael Contelli, Lima, Jonilson Berlink, Araújo-Santos, Théo

“…Patients with severe coronavirus disease 2019 (COVID-19) often present with coagulopathies and have high titres of circulating antibodies against viral…”
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Clinical, epidemiological and transmission cycle aspects of leishmaniasis urbanization in Barreiras, Bahia, Brazil by Lacerda, Alexandre Faria Alvares, Oliveria, Denise Santana, Salomão, Juliane Vilela Fereira, Oliveira, Luiz Gustavo Rodrigues, Monte-Alegre, Adriano, Santos, José Yure Gomes dos, Souza, Carolina Carvalho de, Magalhães-Junior, Jairo Torres, Araújo-Santos, e Théo

“…Leishmaniasis remains one of the world's leading infectious diseases and a public health problem for Bahia and Brazil. We made a retrospective cohort study of…”
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Polyunsaturated fatty acids alter the formation of lipid droplets and eicosanoid production in Leishmania promastigotes by Andrade, Yasmin Monara Ferreira de Sousa, Castro, Monara Viera de, Tavares, Victor de Souza, Souza, Rayane da Silva Oliveira, Faccioli, Lúcia Helena, Lima, Jonilson Berlink, Sorgi, Carlos Arterio, Borges, Valéria M, Araújo-Santos, Théo

“…The knowledge about eicosanoid metabolism and lipid droplet (LD) formation in the Leishmania is very limited and new approaches are needed to identify which…”
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Role of Prostaglandin F2αProduction in Lipid Bodies From Leishmania infantum chagasi: Insights on Virulence by Araújo-Santos, Théo, Rodríguez, Nilda E., Moura-Pontes, Sara, Dixt, Upasna Gaur, Abánades, Daniel R., Bozza, Patricia T., Wilson, Mary E., Borges, Valéria Matos

“…Lipid bodies (LB; lipid droplets) are cytoplasmic organdies involved in lipid metabolism. Mammalian LBs display an important role in host-pathogen…”
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Leishmania infantum lipophosphoglycan induced-Prostaglandin E2 production in association with PPAR-γ expression via activation of Toll like receptors-1 and 2 by Lima, Jonilson Berlink, Araújo-Santos, Théo, Lázaro-Souza, Milena, Carneiro, Alan Brito, Ibraim, Izabela Coimbra, Jesus-Santos, Flávio Henrique, Luz, Nívea Farias, Pontes, Sara de Moura, Entringer, Petter Franco, Descoteaux, Albert, Bozza, Patrícia Torres, Soares, Rodrigo Pedro, Borges, Valéria Matos

“…Lipophosphoglycan (LPG) is a key virulence factor expressed on the surfaces of Leishmania promastigotes. Although LPG is known to activate macrophages, the…”
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Lipid droplets of protozoan parasites: survival and pathogenicity by Tavares, Victor de Souza, de Castro, Monara Viera, Souza, Rayane da Silva Oliveira, Gonçalves, Iana Kátia Araújo, Lima, Jonilson Berlink, Borges, Valéria de Matos, Araújo-Santos, Théo

“…Lipid droplets (LDs; lipid bodies) are intracellular sites of lipid storage and metabolism present in all cell types. Eukaryotic LDs are involved in eicosanoid…”
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Heme oxygenase-1 promotes the persistence of Leishmania chagasi infection by Luz, Nívea F, Andrade, Bruno B, Feijó, Daniel F, Araújo-Santos, Théo, Carvalho, Graziele Q, Andrade, Daniela, Abánades, Daniel R, Melo, Enaldo V, Silva, Angela M, Brodskyn, Cláudia I, Barral-Netto, Manoel, Barral, Aldina, Soares, Rodrigo P, Almeida, Roque P, Bozza, Marcelo T, Borges, Valéria M

“…Visceral leishmaniasis (VL) remains a major public health problem worldwide. This disease is highly associated with chronic inflammation and a lack of the…”
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Associations between TGF- β 1 Levels and Markers of Hemolysis, Inflammation, and Tissue Remodeling in Pediatric Sickle Cell Patients by Santiago, Rayra P, Carvalho, Magda O S, Figueiredo, Camylla V B, Fiuza, Luciana M, Oliveira, Rodrigo M, Yahouédéhou, Sètondji C M A, Nascimento, Valma M L, Lyra, Isa M, Araujo-Santos, Théo, Luz, Nívea F, Aleluia, Milena M, Guarda, Caroline C, Borges, Valéria M, Goncalves, Marilda S

“…Transforming growth factor beta (TGF- ) is a cytokine with important involvement in biological processes related to the pathogenesis of sickle cell disease…”
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