Search Results - "Araujo, Alex Sander"
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Development and validation of a specific-stability indicating liquid chromatography method for quantitative analysis of pterostilbene: application in food and pharmaceutical products
Published in Analytical methods (17-09-2020)“…Pterostilbene is a natural constituent with numerous preventive and therapeutic properties used for treating a wide range of human diseases. It has been…”
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2
Blueberry extract attenuates norepinephrine-induced oxidative stress and apoptosis in H9c2 cardiac cells
Published in Molecular and cellular biochemistry (01-03-2022)“…Enhanced sympathetic system activation mediated by norepinephrine (NE) contributes to adverse cardiac remodeling leading to oxidative stress and cell death,…”
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3
Treatment with thyroid hormones and grape juice in a model of pulmonary hypertension: the response of apoptosis and inflammation
Published in Anais da Academia Brasileira de Ciências (2024)“…This study explored the association of cardioprotective role of thyroid hormones (TH) and benefit effects of grape juice (GJ) on vascular function against the…”
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DHEA Treatment Effects on Redox Environment in Skeletal Muscle of Young and Aged Healthy Rats
Published in Current aging science (2018)“…Dehydroepiandrosterone (DHEA) is an important precursor of active steroid hormone, produced abundantly by the adrenal cortex with an age-dependent pattern. We…”
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Bucindolol Modulates Cardiac Remodeling by Attenuating Oxidative Stress in H9c2 Cardiac Cells Exposed to Norepinephrine
Published in Oxidative medicine and cellular longevity (2019)“…The increased circulation of norepinephrine, found in the diseased heart as a result of sympathetic nervous system overactivation, is responsible for its…”
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6
Effect of free and nanoencapsulated copaiba oil on monocrotaline-induced pulmonary arterial hypertension
Published in Journal of cardiovascular pharmacology (01-02-2017)“…ABSTRACTCopaiba oil comes from an Amazonian tree and has been used as an alternative medicine in Brazil. However, it has not been investigated yet in the…”
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Influence of ovariectomy on cardiac oxidative stress in a renovascular hypertension model
Published in Canadian journal of physiology and pharmacology (01-09-2012)“…The aim of this study was to evaluate the potential influence of endogenous ovarian hormones on cardiac oxidative stress in renovascular hypertension. Female…”
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Decreased PGC1-α levels and increased apoptotic protein signaling are associated with the maladaptive cardiac hypertrophy in hyperthyroidism
Published in Journal of biosciences (01-12-2018)“…Hyperthyroidism can lead to the activation of proteins which are associated with inflammation, apoptosis, hypertrophy, and heart failure. This study aimed to…”
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An early stage in T4-induced hyperthyroidism is related to systemic oxidative stress but does not influence the pentose cycle in erythrocytes and systemic inflammatory status
Published in Archives of Endocrinology and Metabolism (01-05-2019)“…Hyperthyroidism causes many injuries in its target organs and the consequences are reflected systemically. As systemic alterations in hyperthyroidism at…”
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Circulating extracellular vesicles in the aging process: impact of aerobic exercise
Published in Molecular and cellular biochemistry (01-03-2018)“…Our aim was to investigate transitory and delayed exercise effects on serum extracellular vesicles (EVs) in aging process. Male Wistar rats of 3-, 21-, and…”
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Photobiomodulation improves cell survival and death parameters in cardiomyocytes exposed to hypoxia/reoxygenation
Published in Journal of photochemistry and photobiology. B, Biology (01-09-2024)“…Cardiovascular diseases are the leading cause of morbidity and mortality worldwide. Ischemic heart disease is one of the most harmful conditions to cellular…”
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12
Melatonin improves nitric oxide bioavailability in isoproterenol induced myocardial injury
Published in Molecular and cellular endocrinology (15-09-2024)“…Isoproterenol administration is associated with cardiac inflammation and decreased NO availability. Melatonin has been reported to have cardioprotective…”
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13
Vascular Response of Triiodothyronine on Isolated Aortic Rings: Contribution of Redox Mechanisms
Published in Arquivos brasileiros de cardiologia (01-04-2024)“…Vascular dysfunction constitutes the etiology of many diseases, such as myocardial infarction and hypertension, with the disruption of redox homeostasis…”
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14
Antioxidant system disturbances and mitochondrial dysfunction induced by 3-methyglutaric acid in rat heart are prevented by bezafibrate
Published in European journal of pharmacology (05-06-2022)“…Barth syndrome (BTHS) and dilated cardiomyopathy with ataxia syndrome (DCMA) are biochemically characterized by high levels of 3-methylglutaric acid (MGA) in…”
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15
Blueberry extract improves redox balance and functional parameters in the right ventricle from rats with pulmonary arterial hypertension
Published in European journal of nutrition (01-02-2022)“…Purpose Pulmonary arterial hypertension (PAH) is a disease characterized by increased pulmonary vascular resistance and right ventricle (RV) failure. In this…”
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Nicotinamide riboside reduces cardiometabolic risk factors and modulates cardiac oxidative stress in obese Wistar rats under caloric restriction
Published in Life sciences (1973) (15-12-2020)“…NAD-based therapeutic strategies are encouraged against obesity and heart disease. Our study, therefore, aimed to investigate the effects of nicotinamide…”
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Effects of Pterostilbene on Heart and Lung Oxidative Stress Parameters in 2 Experimental Models of Cardiovascular Disease: Myocardial Infarction and Pulmonary Arterial Hypertension
Published in Journal of cardiovascular pharmacology (01-07-2024)“…Myocardial infarction (MI) and pulmonary arterial hypertension (PAH) are 2 prevalent cardiovascular diseases. In both conditions, oxidative stress is…”
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The progression of pulmonary arterial hypertension induced by monocrotaline is characterized by lung nitrosative and oxidative stress, and impaired pulmonary artery reactivity
Published in European journal of pharmacology (15-01-2021)“…The time-course of pulmonary arterial hypertension in the monocrotaline (MCT) model was investigated. Male rats were divided into two groups: MCT (received a…”
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19
Effects of sleep restriction during pregnancy on the mother and fetuses in rats
Published in Physiology & behavior (01-03-2016)“…Abstract The present study aimed to analyze the effects of sleep restriction (SR) during pregnancy in rats. The following three groups were studied: home cage…”
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Cardioprotective effects of thyroid hormones in a rat model of myocardial infarction are associated with oxidative stress reduction
Published in Molecular and cellular endocrinology (25-06-2014)“…•This study evaluated thyroid hormones effects in oxidative stress after infarction.•T3 and T4 administration reduced ROS levels induced by myocardial…”
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