Search Results - "Arati, S"

CAR T-cell therapy for glioblastoma: recent clinical advances and future challenges by Bagley, Stephen J, Desai, Arati S, Linette, Gerald P, June, Carl H, O'Rourke, Donald M

“…In patients with certain hematologic malignancies, the use of autologous T cells genetically modified to express chimeric antigen receptors (CARs) has led to…”
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On Riesz duals for Gabor systems on LCA groups by Arati, S., Devaraj, P.

“…In the context of separable uniform time-frequency lattices in locally compact abelian groups, we analyse the circumstances in which, for a given Gabor frame,…”
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Intrathecal bivalent CAR T cells targeting EGFR and IL13Rα2 in recurrent glioblastoma: phase 1 trial interim results by Bagley, Stephen J., Logun, Meghan, Fraietta, Joseph A., Wang, Xin, Desai, Arati S., Bagley, Linda J., Nabavizadeh, Ali, Jarocha, Danuta, Martins, Rene, Maloney, Eileen, Lledo, Lester, Stein, Carly, Marshall, Amy, Leskowitz, Rachel, Jadlowsky, Julie K., Christensen, Shannon, Oner, Bike Su, Plesa, Gabriela, Brennan, Andrea, Gonzalez, Vanessa, Chen, Fang, Sun, Yusha, Gladney, Whitney, Barrett, David, Nasrallah, MacLean P., Hwang, Wei-Ting, Ming, Guo-Li, Song, Hongjun, Siegel, Donald L., June, Carl H., Hexner, Elizabeth O., Binder, Zev A., O’Rourke, Donald M.

“…Recurrent glioblastoma (rGBM) remains a major unmet medical need, with a median overall survival of less than 1 year. Here we report the first six patients…”
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Clinical measures, radiomics, and genomics offer synergistic value in AI-based prediction of overall survival in patients with glioblastoma by Fathi Kazerooni, Anahita, Saxena, Sanjay, Toorens, Erik, Tu, Danni, Bashyam, Vishnu, Akbari, Hamed, Mamourian, Elizabeth, Sako, Chiharu, Koumenis, Costas, Verginadis, Ioannis, Verma, Ragini, Shinohara, Russell T., Desai, Arati S., Lustig, Robert A., Brem, Steven, Mohan, Suyash, Bagley, Stephen J., Ganguly, Tapan, O’Rourke, Donald M., Bakas, Spyridon, Nasrallah, MacLean P., Davatzikos, Christos

“…Multi-omic data, i.e., clinical measures, radiomic, and genetic data, capture multi-faceted tumor characteristics, contributing to a comprehensive patient risk…”
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Histopathology‐validated machine learning radiographic biomarker for noninvasive discrimination between true progression and pseudo‐progression in glioblastoma by Akbari, Hamed, Rathore, Saima, Bakas, Spyridon, Nasrallah, MacLean P., Shukla, Gaurav, Mamourian, Elizabeth, Rozycki, Martin, Bagley, Stephen J., Rudie, Jeffrey D., Flanders, Adam E., Dicker, Adam P., Desai, Arati S., O’Rourke, Donald M., Brem, Steven, Lustig, Robert, Mohan, Suyash, Wolf, Ronald L., Bilello, Michel, Martinez‐Lage, Maria, Davatzikos, Christos

“…Background Imaging of glioblastoma patients after maximal safe resection and chemoradiation commonly demonstrates new enhancements that raise concerns about…”
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Clinical Utility of Plasma Cell-Free DNA in Adult Patients with Newly Diagnosed Glioblastoma: A Pilot Prospective Study by Bagley, Stephen J, Nabavizadeh, S Ali, Mays, Jazmine J, Till, Jacob E, Ware, Jeffrey B, Levy, Scott, Sarchiapone, Whitney, Hussain, Jasmin, Prior, Timothy, Guiry, Samantha, Christensen, Theresa, Yee, Stephanie S, Nasrallah, MacLean P, Morrissette, Jennifer J D, Binder, Zev A, O'Rourke, Donald M, Cucchiara, Andrew J, Brem, Steven, Desai, Arati S, Carpenter, Erica L

“…The clinical utility of plasma cell-free DNA (cfDNA) has not been assessed prospectively in patients with glioblastoma (GBM). We aimed to determine the…”
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The University of Pennsylvania glioblastoma (UPenn-GBM) cohort: advanced MRI, clinical, genomics, & radiomics by Bakas, Spyridon, Sako, Chiharu, Akbari, Hamed, Bilello, Michel, Sotiras, Aristeidis, Shukla, Gaurav, Rudie, Jeffrey D., Santamaría, Natali Flores, Kazerooni, Anahita Fathi, Pati, Sarthak, Rathore, Saima, Mamourian, Elizabeth, Ha, Sung Min, Parker, William, Doshi, Jimit, Baid, Ujjwal, Bergman, Mark, Binder, Zev A., Verma, Ragini, Lustig, Robert A., Desai, Arati S., Bagley, Stephen J., Mourelatos, Zissimos, Morrissette, Jennifer, Watt, Christopher D., Brem, Steven, Wolf, Ronald L., Melhem, Elias R., Nasrallah, MacLean P., Mohan, Suyash, O’Rourke, Donald M., Davatzikos, Christos

“…Glioblastoma is the most common aggressive adult brain tumor. Numerous studies have reported results from either private institutional data or publicly…”
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Decoding the impact of solvents in altering the conversion rates and stereoselectivity in proline-catalyzed asymmetric aldol reaction by Gavali, Arati S., Maliekal, Parimal J., Naik, Vaishnavi A., Badani, Purav M.

“…The choice of solvent plays a crucial role in aldol reactions, often affecting both the conversion rate and stereoselectivity. In this study, we investigated…”
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Switching the regio-, stereo- and enantioselectivity in L-proline catalyzed asymmetric Mannich reaction: A case study of H-acceptor and H-donor solvents by Maliekal, Parimal J, Gavali, Arati S, Patel, Priyanka, Badani, Purav M.

“…We report the detailed mechanistic insights of L-proline catalyzed, solvent-controlled, regioselective Mannich reaction. Different solvation models were…”
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Sociability Deficits and Altered Amygdala Circuits in Mice Lacking Pcdh10 , an Autism Associated Gene by Schoch, Hannah, Kreibich, Arati S, Ferri, Sarah L, White, Rachel S, Bohorquez, Dominique, Banerjee, Anamika, Port, Russell G, Dow, Holly C, Cordero, Lucero, Pallathra, Ashley A, Kim, Hyong, Li, Hongzhe, Bilker, Warren B, Hirano, Shinji, Schultz, Robert T, Borgmann-Winter, Karin, Hahn, Chang-Gyu, Feldmeyer, Dirk, Carlson, Gregory C, Abel, Ted, Brodkin, Edward S

“…Abstract Background Behavioral symptoms in individuals with autism spectrum disorder (ASD) have been attributed to abnormal neuronal connectivity, but the…”
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Quantification of tumor microenvironment acidity in glioblastoma using principal component analysis of dynamic susceptibility contrast enhanced MR imaging by Akbari, Hamed, Kazerooni, Anahita Fathi, Ware, Jeffrey B., Mamourian, Elizabeth, Anderson, Hannah, Guiry, Samantha, Sako, Chiharu, Raymond, Catalina, Yao, Jingwen, Brem, Steven, O’Rourke, Donald M., Desai, Arati S., Bagley, Stephen J., Ellingson, Benjamin M., Davatzikos, Christos, Nabavizadeh, Ali

“…Glioblastoma (GBM) has high metabolic demands, which can lead to acidification of the tumor microenvironment. We hypothesize that a machine learning model…”
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Risk of intracranial hemorrhage with direct oral anticoagulants vs low molecular weight heparin in glioblastoma: A retrospective cohort study by Reed-Guy, Lauren, Desai, Arati S, Phillips, Richard E, Croteau, Desiree, Albright, Karen, O'Neill, Meghan, Brem, Steven, O'Rourke, Donald M, Amankulor, Nduka M, Bagley, Stephen J

“…Glioblastoma (GBM) is associated with a high incidence of venous thromboembolism (VTE), but there are little data to guide anticoagulation in patients with…”
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Activation of basolateral amygdala in juvenile C57BL/6J mice during social approach behavior by Ferri, Sarah L, Kreibich, Arati S, Torre, Matthew, Piccoli, Cara T, Dow, Holly, Pallathra, Ashley A, Li, Hongzhe, Bilker, Warren B, Gur, Ruben C, Abel, Ted, Brodkin, Edward S

“…Highlights • Juvenile C57BL/6J male mice exhibit high social approach behavior in a three-chamber apparatus. • Social approach preferentially activates the…”
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Role of APOE and IL18RAP gene polymorphisms in cervical spondylotic myelopathy in Indian population by Diptiranjan, S., Harshitha, S.M., Sibin, M.K., Arati, S., Chetan, G.K., Bhat, Dhananjaya I.

“…•Cervical spondylotic myelopathy (CSM) is a progressive degenerative spine disease.•APOE gene polymorphism was associated with the risk of CSM.•There was no…”
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Case Report: Prolonged Survival Following EGFRvIII CAR T Cell Treatment for Recurrent Glioblastoma by Durgin, Joseph S., Henderson, Fraser, Nasrallah, MacLean P., Mohan, Suyash, Wang, Sumei, Lacey, Simon F., Melenhorst, Jan Joseph, Desai, Arati S., Lee, John Y. K., Maus, Marcela V., June, Carl H., Brem, Steven, O’Connor, Roddy S., Binder, Zev, O’Rourke, Donald M.

“…Autologous chimeric antigen receptor (CAR) T cells targeted to epidermal growth factor receptor variant III (CAR T-EGFRvIII) have been developed and…”
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Quality of life in patients with locally advanced head and neck squamous cell carcinoma undergoing concurrent chemoradiation with once-a-week versus once-every-3-weeks cisplatin by Menon, Nandini S, Noronha, Vanita, Patil, Vijay Maruti, Joshi, Amit, Bhattacharjee, Atanu, Kalra, Devanshi, Laskar, Sarbani Ghosh, Mathrudev, Vijayalakshmi, Nawale, Kavita, Bhelekar, Arati S, Prabhash, Kumar

“…This trial was conducted to compare the efficacy of low dose once-a-week cisplatin and once-every-3-weeks cisplatin with radiation in locally advanced head and…”
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Green synthesis and DFT study of orthoaminocarbonitrile methyl tetrahydronaphthalene using WEPA: water extract of pomegranate ash as a sustainable catalyst by Dafale, Pankaj S., Ingale, Vivek S., Gavali, Arati S., Badani, Purav M., Patil, Kiran N.

“…Water Extract of Pomegranate Ash (WEPA) emerges as a highly effective green catalyst in the one-pot multicomponent synthesis of orthoaminocarbonitrile…”
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Oral Manifestations of Diabetes by Indurkar, Maya S, Maurya, Arati S, Indurkar, Sanjiv

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Clinical activity of the EGFR tyrosine kinase inhibitor osimertinib in EGFR -mutant glioblastoma by Makhlin, Igor, Salinas, Ryan D, Zhang, Daniel, Jacob, Fadi, Ming, Gou-Li, Song, Hongjun, Saxena, Deeksha, Dorsey, Jay F, Nasrallah, MacLean P, Morrissette, Jennifer Jd, Binder, Zev A, O'Rourke, Donald M, Desai, Arati S, Brem, Steven, Bagley, Stephen J

“…Glioblastoma (GBM) is the most common primary malignant brain tumor in adults and carries a dismal prognosis. The gene is among the most commonly deranged…”
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Quantitative estimation of vertical heights of maxillary and mandibular jawbones in elderly dentate and edentulous subjects by Panchbhai, Arati S.

“…ABSTRACT The residual alveolar ridge resorption is inevitable with aging. The purpose of the study was to determine and compare differences in the vertical…”
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