Search Results - "Aras, Abdülmelik"

Synthesis of two novel mercaptobenzimidazole derivative Schiff bases and their in vitro antioxidant and enzyme inhibitory effects by Aras, Abdülmelik

“…In this study, 5-(2-hydroxy-4-methoxybenzylidenamino)-2-mercaptobenzimidazole and 5-(4-hydroxy-3-methoxybenzylidenamino)-2-mercaptobenzimidazole Schiff base…”
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LC/MS/MS Phenolic Profile, Antioxidant Capacity, Angiotensin‐Converting Enzyme (ACE) and Glutathione S Transferase (GST) Inhibitory Properties of Ultrasound‐Assisted Propolis Extracts by Aras, Abdülmelik, Korkmaz, Tuğba, Bayrakdar, Alpaslan

“…Resinous beehive product propolis has many biological activities. It contains various aromatic substances that have great differences in their chemical…”
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Evaluation of antioxidant capacity of endemic plant Marrubium astracanicum subsp. macrodon: Identification of its phenolic contents by using HPLC-MS/MS by Bursal, Ercan, Aras, Abdülmelik, Kılıç, Ömer

“…Antioxidant properties of Marrubium astracanicum subsp. macrodon solvent extracts were measured by both cupric ion reducing antioxidant capacity (CUPRAC) and…”
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ICP-MS and HPLC analyses, enzyme inhibition and antioxidant potential of Achillea schischkinii Sosn by Türkan, Fikret, Atalar, Mehmet Nuri, Aras, Abdülmelik, Gülçin, İlhami, Bursal, Ercan

“…[Display omitted] •Acetylcholinesterase, butyrylcholinesterase, α-glycosidase, and glutathione s-transferase enzymes have crucial functions on…”
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Anti-Alzheimer, antidiabetic and antioxidant potential of Satureja cuneifolia and analysis of its phenolic contents by LC-MS/MS by Taslimi, Parham, Köksal, Ekrem, Gören, Ahmet C., Bursal, Ercan, Aras, Abdülmelik, Kılıç, Ömer, Alwasel, Saleh, Gülçin, İlhami

“…Many chronic diseases such as diabetes and Alzheimer’s disease are related to the type and quality of foods, which are consumed. Particularly, various plant…”
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Enzyme inhibitory function and phytochemical profile of Inula discoidea using in vitro and in silico methods by Bursal, Ercan, Yılmaz, Mustafa Abdullah, Izol, Ebubekir, Türkan, Fikret, Atalar, Mehmet Nuri, Murahari, Manikanta, Aras, Abdülmelik, Ahmad, Mushtaq

“…Many plant species have a large diversity of secondary metabolites with different biological activities. This study aims to assess the phenolic constituent,…”
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Biochemical constituent, enzyme inhibitory activity, and molecular docking analysis of an endemic plant species, Thymus migricus by Aras, Abdülmelik, Türkan, Fikret, Yildiko, Umit, Atalar, Mehmet Nuri, Kılıç, Ömer, Alma, Mehmet Hakki, Bursal, Ercan

“…Medicinal plants have been used traditionally since ancient times as alternative medications to treat various human diseases . In this work, we examined the…”
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Synthesis and in silico studies of Novel Ru(II) complexes of Schiff base derivatives of 3-[(4-amino-5-thioxo-1,2,4-triazole-3-yl)methyl]-2(3H)-benzoxazolone compounds as potent Glutathione S-transferase and Cholinesterases Inhibitor by Adiguzel, Ragip, Türkan, Fikret, Yildiko, Ümit, Aras, Abdülmelik, Evren, Enes, Onkol, Tijen

“…•İn this study novel Ru(II) complexes of Shiff base derivatives were synthesized.•IC50 and Ki values of inhibition studies were calculated…”
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Determination of anticancer properties and inhibitory effects of some metabolic enzymes including acetylcholinesterase, butyrylcholinesterase, alpha-glycosidase of some compounds with molecular docking study by Türkan, Fikret, Taslimi, Parham, Abdalrazaq, Sakar Mübarak, Aras, Abdülmelik, Erden, Yavuz, Celebioglu, Hasan Ufuk, Tuzun, Burak, Ağırtaş, Mehmet Salih, Gülçin, İlhami

“…Inhibitory effect of the complexes on some metabolic enzyme demonstrated that the enzymes inhibited by ligand and it's complex molecules at the micromolar…”
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Assessment of Antimicrobial and Antioxidant Activities of Nepeta trachonitica: Analysis of Its Phenolic Compounds Using HPLC-MS/MS by Köksal, Ekrem, Tohma, Hatice, Kılıç, Ömer, Alan, Yusuf, Aras, Abdülmelik, Gülçin, İlhami, Bursal, Ercan

“…Continuing our work on the sources of natural bioactive compounds, we evaluated the antimicrobial and antioxidant activities of as well as its major phenolic…”
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Synthesis, characterization of novel mannich bases and their acetylcholinesterase and glutathione S-transferase inhibitory properties: An in vitro and in silico mechanism research by Toraman, Gül Özdemir, Bayrakdar, Alpaslan, Oğuz, Ercan, Beytur, Murat, Türkan, Fikret, Manap, Sevda, Aras, Abdülmelik, Yüksek, Haydar

“…•New Mannich Bases derived from 1,2,4-Triazoles synthesis, characterization.•Testing of the inhibition activity of new compounds against AChE and GST as…”
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Phytochemical Content, Antidiabetic, Anticholinergic, and Antioxidant Activities of Endemic Lecokia cretica Extracts by Aras, Abdülmelik, Bursal, Ercan, Türkan, Fikret, Tohma, Hatice, Kılıç, Ömer, Gülçin, İlhami, Köksal, Ekrem

“…The aim of this work was to investigate the enzyme inhibition, antioxidant activity, and phenolic compounds of Lecokia cretica (Lam.) DC. Acetylcholinesterase…”
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Synthesis, Spectroscopic Analysis, and in Vitro/in Silico Biological Studies of Novel Piperidine Derivatives Heterocyclic Schiff‐Mannich Base Compounds by Boy, Songül, Aras, Abdülmelik, Türkan, Fikret, Akyıldırım, Onur, Beytur, Murat, Sedef Karaman, Halide, Manap, Sevda, Yüksek, Haydar

“…In the present study, 3‐substitued‐4‐(4‐hydroxybenzylidenamino)‐4,5‐dihydro‐1H‐1,2,4‐triazol‐5‐ones (S1‐8) were synthesized by treating 4‐hydroxybenzaldehyde…”
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Synthesis, design, and assessment of novel morpholine-derived Mannich bases as multifunctional agents for the potential enzyme inhibitory properties including docking study by Boy, Songül, Türkan, Fikret, Beytur, Murat, Aras, Abdülmelik, Akyıldırım, Onur, Karaman, Halide Sedef, Yüksek, Haydar

“…[Display omitted] •New morpholine derived Schiff bases substituents.•Results of the inhibition activity against AChE, BChE, and GST.•Docking studies of Schiff…”
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Synthesis and Characterization of Azo Dye Complexes as Potential Inhibitors of Acetylcholinesterase, Butyrylcholinesterase, and Glutathione S‐Transferase by Buldurun, Kenan, Aras, Abdülmelik, Turan, Nevin, Turkan, Fikret, Adiguzel, Ragip, Bursal, Ercan

“…In this study, several metal(II) complexes (Fe, Co, Zn, and Ru) of an azo dye ligand (ADL) that, apart from pyrazole ring (PR), include anisole having (−OCH3)…”
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Synthesis of novel 1,2,3 triazole derivatives and assessment of their potential cholinesterases, glutathione S-transferase enzymes inhibitory properties: An in vitro and in silico study by Çelik, Fatih, Türkan, Fikret, Aras, Abdülmelik, Atalar, Mehmet Nuri, Karaman, Halide Sedef, Ünver, Yasemin, Kahriman, Nuran

“…[Display omitted] •New 1,2,3-triazole derivatives containing chalcone (1–7) were synthesized.•All newly compounds were characterized by IR, 1H NMR, 13C NMR and…”
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The effects of Daucus carota extract against PC3, PNT1a prostate cells, acetylcholinesterase, glutathione S‐transferase, and α‐glycosidase; an in vitro–in silico study by Atalar, Mehmet Nuri, Aras, Abdülmelik, Türkan, Fikret, Barlak, Neslisah, Yildiko, Ümit, Karatas, Omer Faruk, Alma, Mehmet Hakkı

“…Daucus carota L. ssp. major (DCM) plant is widely used in traditional medicine to treat some types of cancer and various diseases. Therefore, we evaluated the…”
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Metal contained Phthalocyanines with 3,4-Dimethoxyphenethoxy substituents: their anticancer, antibacterial activities and their inhibitory effects on some metabolic enzymes with molecular docking studies by Taslimi, Parham, Türkan, Fikret, Güngördü Solğun, Derya, Aras, Abdülmelik, Erden, Yavuz, Celebioglu, Hasan Ufuk, Tuzun, Burak, Ağırtaş, Mehmet Salih, Günay, Sevilay, Gulcin, Ilhami

“…The compounds (3-6) used in this study were re-synthesized in accordance with our previous study. The inhibitory effect of the complexes on some metabolic…”
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Transition metal complexes of a multidentate Schiff base ligand containing pyridine: synthesis, characterization, enzyme inhibitions, antioxidant properties, and molecular docking studies by Bursal, Ercan, Turkan, Fikret, Buldurun, Kenan, Turan, Nevin, Aras, Abdulmelik, Çolak, Naki, Murahari, Manikanta, Yergeri, Mayur C.

“…A series of Fe(II), Ni(II), and Pd(II) complexes were prepared with a novel Schiff base ligand containing pyridine moiety. The prepared compounds were…”
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Novel Mannich bases derived from 1,2,4-triazoles: Design, synthesis, characterization, and glutathione S-transferase inhibition properties investigations by Akyıldırım, Onur, Medetalibeyoğlu, Hilal, Oğuz, Ercan, Aras, Abdülmelik, Atalay, Abdurrahman, Korkmaz, Adem, Beytur, Murat, Türkan, Fikret, Yüksek, Haydar

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