Search Results - "Aranyos, Alek M"

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  1. 1

    Berberine potentiates liver inflammation and fibrosis in the PIZ hAAT transgenic murine model by Lu, Yuanqing, Mohammad, Naweed S, Lee, Jungnam, Aranyos, Alek M, Serban, Karina A, Brantly, Mark L

    Published in PloS one (19-09-2024)
    “…Alpha-1 antitrypsin deficiency (AATD) is an inherited disease, the common variant caused by a Pi*Z mutation in the SERPINA1 gene. Pi*Z AAT increases the risk…”
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    Journal Article
  2. 2

    The Mechanism of Mitochondrial Injury in Alpha-1 Antitrypsin Deficiency Mediated Liver Disease by Khodayari, Nazli, Wang, Rejean L, Oshins, Regina, Lu, Yuanqing, Millett, Michael, Aranyos, Alek M, Mostofizadeh, Sayedamin, Scindia, Yogesh, Flagg, Tammy O, Brantly, Mark

    “…Alpha-1 antitrypsin deficiency (AATD) is caused by a single mutation in the SERPINA1 gene, which culminates in the accumulation of misfolded alpha-1…”
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    Journal Article
  3. 3

    The unfolded protein response to PIZ alpha‐1 antitrypsin in human hepatocellular and murine models by Lu, Yuanqing, Wang, Liqun R., Lee, Jungnam, Mohammad, Naweed S., Aranyos, Alek M., Gould, Calvin, Khodayari, Nazli, Oshins, Regina A., Moneypenny, Craig G., Brantly, Mark L.

    Published in Hepatology communications (01-09-2022)
    “…Alpha‐1 antitrypsin (AAT) deficiency (AATD) is an inherited disease caused by mutations in the serpin family A member 1 (SERPINA1, also known as AAT) gene. The…”
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    Journal Article
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    Characterization of hepatic inflammatory changes in a C57BL/6J mouse model of alpha1-antitrypsin deficiency by Khodayari, Nazli, Oshins, Regina, Aranyos, Alek M, Duarte, Sergio, Mostofizadeh, Sayedamin, Lu, Yuanqing, Brantly, Mark

    “…Alpha-1 antitrypsin deficiency (AATD) is a genetic disease caused by a hepatic accumulation of mutant alpha-1 antitrypsin (ZAAT). Individuals with AATD are…”
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    Journal Article
  6. 6

    Utilization of Feline ELISpot to Evaluate the Immunogenicity of a T Cell-Based FIV MAP Vaccine by Sahay, Bikash, Aranyos, Alek M, McAvoy, Andrew, Yamamoto, Janet K

    “…The prototype and the commercial dual-subtype feline immunodeficiency virus (FIV) vaccines conferred protection against homologous FIV strains as well as…”
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    Journal Article
  7. 7

    An initial examination of the potential role of T-cell immunity in protection against feline immunodeficiency virus (FIV) infection by Aranyos, Alek M, Roff, Shannon R, Pu, Ruiyu, Owen, Jennifer L, Coleman, James K, Yamamoto, Janet K

    Published in Vaccine (14-03-2016)
    “…Highlights • 23/33 recipients of adoptive T-cell transfer from vaccinated donors were protected. • 81% (17/21) protection was against homologous FIV (vaccine…”
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    Journal Article
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