Search Results - "Aranyos, Alek M"
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Berberine potentiates liver inflammation and fibrosis in the PIZ hAAT transgenic murine model
Published in PloS one (19-09-2024)“…Alpha-1 antitrypsin deficiency (AATD) is an inherited disease, the common variant caused by a Pi*Z mutation in the SERPINA1 gene. Pi*Z AAT increases the risk…”
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The Mechanism of Mitochondrial Injury in Alpha-1 Antitrypsin Deficiency Mediated Liver Disease
Published in International journal of molecular sciences (09-12-2021)“…Alpha-1 antitrypsin deficiency (AATD) is caused by a single mutation in the SERPINA1 gene, which culminates in the accumulation of misfolded alpha-1…”
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The unfolded protein response to PIZ alpha‐1 antitrypsin in human hepatocellular and murine models
Published in Hepatology communications (01-09-2022)“…Alpha‐1 antitrypsin (AAT) deficiency (AATD) is an inherited disease caused by mutations in the serpin family A member 1 (SERPINA1, also known as AAT) gene. The…”
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Immunogenicity and Efficacy of a Novel Multi-Antigenic Peptide Vaccine Based on Cross-Reactivity between Feline and Human Immunodeficiency Viruses
Published in Viruses (03-02-2019)“…For the development of an effective HIV-1 vaccine, evolutionarily conserved epitopes between feline and human immunodeficiency viruses (FIV and HIV-1) were…”
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Characterization of hepatic inflammatory changes in a C57BL/6J mouse model of alpha1-antitrypsin deficiency
Published in American journal of physiology: Gastrointestinal and liver physiology (01-12-2022)“…Alpha-1 antitrypsin deficiency (AATD) is a genetic disease caused by a hepatic accumulation of mutant alpha-1 antitrypsin (ZAAT). Individuals with AATD are…”
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Utilization of Feline ELISpot to Evaluate the Immunogenicity of a T Cell-Based FIV MAP Vaccine
Published in Methods in molecular biology (Clifton, N.J.) (01-01-2018)“…The prototype and the commercial dual-subtype feline immunodeficiency virus (FIV) vaccines conferred protection against homologous FIV strains as well as…”
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An initial examination of the potential role of T-cell immunity in protection against feline immunodeficiency virus (FIV) infection
Published in Vaccine (14-03-2016)“…Highlights • 23/33 recipients of adoptive T-cell transfer from vaccinated donors were protected. • 81% (17/21) protection was against homologous FIV (vaccine…”
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