Search Results - "Arantes, Lidia Maria Rebolho Batista"
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Alcohol consumption, depression, overweight and cortisol levels as determining factors for NR3C1 gene methylation
Published in Scientific reports (24-03-2021)“…The NR3C1 glucocorticoid receptor (GR) gene is a component of the stress response system, which can be regulated by epigenetic mechanisms. NR3C1 methylation…”
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Evaluation of acetylation and methylation in oral rinse of patients with head and neck cancer history exposed to valproic acid
Published in Scientific reports (12-08-2021)“…Evaluate the biological action of valproic acid in the acetylation of histones and in the methylation of tumor suppressor genes via oral rinse in patients with…”
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In-depth transcriptome reveals the potential biotechnological application of Bothrops jararaca venom gland
Published in The journal of venomous animals and toxins including tropical diseases (21-10-2020)“…Lack of complete genomic data of impedes molecular biology research focusing on biotechnological applications of venom gland components. Identification of…”
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MiR-21 as prognostic biomarker in head and neck squamous cell carcinoma patients undergoing an organ preservation protocol
Published in Oncotarget (07-02-2017)“…Despite progress in the treatment of head and neck squamous cell carcinoma (HNSCC) in recent decades, including new surgical techniques, radiotherapy advances…”
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Impact of genetic variants in clinical outcome of a cohort of patients with oropharyngeal squamous cell carcinoma
Published in Scientific reports (19-06-2020)“…Tobacco- or human papillomavirus- driven oropharyngeal squamous cell carcinomas (OpSCC) represent distinct clinical, biological and epidemiological entities…”
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DNA Methylation Markers from Negative Surgical Margins Can Predict Recurrence of Oral Squamous Cell Carcinoma
Published in Cancers (11-06-2021)“…The identification of molecular markers in negative surgical margins of oral squamous cell carcinoma (OSCC) might help in identifying residual molecular…”
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Clinical and Molecular Characterization of Surgically Treated Oropharynx Squamous Cell Carcinoma Samples
Published in Pathology oncology research (01-07-2019)“…A better understanding of the clinical and molecular features of oropharyngeal squamous cell carcinomas (OPSCC) may help in the development of strategies for a…”
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One-carbon metabolism and global DNA methylation in mothers of individuals with Down syndrome
Published in Human cell : official journal of Human Cell Research Society (01-11-2021)“…Down syndrome (DS) is the most common chromosomal disorder, resulting from the failure of normal chromosome 21 segregation. Studies have suggested that…”
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Psychotropic drug use and suggestive depression symptoms associated with NR3C1 DNA methylation
Published in Revista brasileira de crescimento e desenvolvimento humano (2023)“…Introduction: Psychiatric disorders have become a global problem that leads millions of people to use psychotropic medications, especially benzodiazepines. The…”
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DNMT3B C46359T and SHMT1 C1420T polymorphisms in the folate pathway in carcinogenesis of head and neck
Published in Molecular biology reports (01-02-2014)“…Folate is an essential nutrient with important roles in the synthesis, repair, and DNA methylation. Polymorphisms in genes encoding enzymes involved in folate…”
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Biomarkers for Immune Checkpoint Inhibitor Response in NSCLC: Current Developments and Applicability
Published in International journal of molecular sciences (25-07-2023)“…Lung cancer has the highest mortality rate among all cancer types, resulting in over 1.8 million deaths annually. Immunotherapy utilizing immune checkpoint…”
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Mature tertiary lymphoid structures are key niches of tumour-specific immune responses in pancreatic ductal adenocarcinomas
Published in Gut (01-10-2023)“…To better understand the immune microenvironment of pancreatic ductal adenocarcinomas (PDACs), here we explored the relevance of T and B cell…”
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Methylation of the hsa-miR-124, SOX1, TERT, and LMX1A genes as biomarkers for precursor lesions in cervical cancer
Published in Gynecologic oncology (01-09-2018)“…The methylation profile of genes in precursor lesions in cervical cancer was characterized to improve screening techniques for high-grade intraepithelial…”
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Association of Fusobacterium nucleatum Levels by ddPCR in Oral Rinse Samples With Periodontal Disease in Oral Squamous Cell Carcinoma Patients and in Controls
Published in Journal of oral pathology & medicine (23-10-2024)“…The role of microbiome, particularly Fusobacterium nucleatum (Fn), in periodontal disease and oral squamous cell carcinoma (OSCC) has been recently explored…”
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Combined effect of the pro-apoptotic rhTRAIL protein and HSV-1 virus in head and neck cancer cell lines
Published in Scientific reports (21-10-2023)“…Knowledge on the molecular and clinical characteristics of head and neck squamous cell carcinoma (HNSCC) is vast. However, an effective therapy that increases…”
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Microfluidic-Based Genosensor To Detect Human Papillomavirus (HPV16) for Head and Neck Cancer
Published in ACS applied materials & interfaces (31-10-2018)“…High-risk human papillomavirus (HPV) infection, mainly with HPV16 type, has been increasingly considered as an important etiologic factor in head and neck…”
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Unveiling the role of MGMT and DAPK hypermethylation in response to anti‐EGFR agents: Molecular insights for advancing HNSCC treatment
Published in Head & neck (01-03-2024)“…Background Epidermal growth factor receptor (EGFR) is frequently activated in head and neck squamous cell carcinoma (HNSCC) and serves as a valuable target for…”
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miR-99a-5p as a biomarker for lymph node metastasis prediction in oral squamous cell carcinoma patients
Published in Head & neck (01-10-2023)“…Metastatic lymph node involvement influences therapy decisions and serves as a prognostic indicator in oral squamous cell carcinoma (OSCC). However, many…”
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Clinical and epidemiological characteristics of patients in the head and neck surgery department of a university hospital
Published in São Paulo medical journal (2012)“…Head and neck cancer is the fifth most common type of cancer worldwide. The objective of this study was to evaluate the clinical and epidemiological parameters…”
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Lifestyle and NR3C1 exon 1F gene methylation is associated with changes in glucose levels and insulin resistance
Published in Life sciences (1973) (15-11-2022)“…AIMSthe present study aimed to investigate how glucose and insulin levels may be associated with changes in NR3C1 gene methylation levels in adults. MAIN…”
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