Search Results - "Arango, V"
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Whole-transcriptome brain expression and exon-usage profiling in major depression and suicide: evidence for altered glial, endothelial and ATPase activity
Published in Molecular psychiatry (01-05-2017)“…Brain gene expression profiling studies of suicide and depression using oligonucleotide microarrays have often failed to distinguish these two phenotypes…”
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2
Mortality as an adverse outcome of sarcopenia
Published in The Journal of nutrition, health & aging (01-03-2013)“…Sarcopenia has an important impact in elderly. Recently the European Working Group on Sarcopenia in Older People (EWGSOP) defined sarcopenia as the loss of…”
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3
Elevated expression of tryptophan hydroxylase-2 mRNA at the neuronal level in the dorsal and median raphe nuclei of depressed suicides
Published in Molecular psychiatry (01-05-2008)“…Deficient levels of serotonin are associated with suicide and depression. Paradoxically, in the dorsal raphe nucleus (DRN) there are more serotonin neurons and…”
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4
Region-specific alterations of A-to-I RNA editing of serotonin 2c receptor in the cortex of suicides with major depression
Published in Translational psychiatry (30-08-2016)“…Brain region-specific abnormalities in serotonergic transmission appear to underlie suicidal behavior. Alterations of RNA editing on the serotonin receptor 2C…”
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5
Genetic neuropathology of obsessive psychiatric syndromes
Published in Translational psychiatry (02-09-2014)“…Anorexia nervosa (AN), bulimia nervosa (BN) and obsessive-compulsive disorder (OCD) are complex psychiatric disorders with shared obsessive features, thought…”
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6
The functional serotonin 1a receptor promoter polymorphism, rs6295, is associated with psychiatric illness and differences in transcription
Published in Translational psychiatry (01-03-2016)“…The G/C single-nucleotide polymorphism in the serotonin 1a receptor promoter, rs6295, has previously been linked with depression, suicide and antidepressant…”
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7
Abnormalities of myelination in schizophrenia detected in vivo with MRI, and post-mortem with analysis of oligodendrocyte proteins
Published in Molecular psychiatry (01-09-2003)“…Schizophrenia unfolds during the late period of brain maturation, while myelination is still continuing. In the present study, we used MRI and T2 relaxation…”
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Serotonin 1A Receptors, Serotonin Transporter Binding and Serotonin Transporter mRNA Expression in the Brainstem of Depressed Suicide Victims
Published in Neuropsychopharmacology (New York, N.Y.) (01-12-2001)“…Suicide and depression are associated with reduced serotonergic neurotransmission. In suicides, there is a reduction in serotonin transporter (SERT) sites and…”
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9
Upregulation of CB1 receptors and agonist-stimulated [35S]GTPγS binding in the prefrontal cortex of depressed suicide victims
Published in Molecular psychiatry (01-02-2004)“…Endogenous and exogenous cannabinoids (CBs) acting through the CB1 receptors have been implicated in the regulation of several behavioral and neuroendocrine…”
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10
Unaltered neuronal and glial counts in animal models of magnetic seizure therapy and electroconvulsive therapy
Published in Neuroscience (29-12-2009)“…Abstract Anatomical evidence of brain damage from electroconvulsive therapy (ECT) is lacking; but there are no modern stereological studies in primates…”
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Genetic architecture of the human tryptophan hydroxylase 2 Gene: existence of neural isoforms and relevance for major depression
Published in Molecular psychiatry (01-08-2008)“…Impaired brain serotonin neurotransmission is a potential component of the diathesis of major depression. Tryptophan hydroxylase-2 (TPH2), is the rate limiting…”
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12
The E280A presenilin 1 Alzheimer mutation produces increased Aβ42 deposition and severe cerebellar pathology
Published in Nature medicine (01-10-1996)Get full text
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13
Synaptic and plasticity-associated proteins in anterior frontal cortex in severe mental illness
Published in Neuroscience (01-01-1999)“…Abnormalities of proteins involved in neurotransmission and neural plasticity at synapses are reported in schizophrenia, and may be markers of dysregulated…”
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14
Effectiveness of Native Vitamin D Therapy in Patients with Chronic Kidney Disease Stage 3 and Hypovitaminosis D in Colombia, South America
Published in International journal of nephrology and renovascular disease (01-12-2019)“…In a high percentage of patients with chronic kidney disease (CKD) low levels of vitamin D are detected. The purpose of this study was to evaluate if the…”
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15
Altered immunoreactivity of complexin protein in prefrontal cortex in severe mental illness
Published in Molecular psychiatry (01-01-2002)“…Recent imaging and postmortem studies suggest that impaired connectivity is involved in the pathophysiology of schizophrenia and major affective disorders. We…”
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16
Neuronal tryptophan hydroxylase expression in human dorsal raphe nucleus neurons
Published in Molecular psychiatry (01-05-2008)“…The upper panel is an in situ hybridization film autoradiogram of a human brainstem section expressing neuronal tryptophan hydroxylase (TPH2) mRNA, obtained…”
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17
Corticotropic-releasing hormone and serotonin interact in the human brainstem: behavioral implications
Published in Neuroscience (01-01-1999)“…The objective of this human post mortem study was to determine whether neurons which synthesize corticotropic-releasing hormone and serotonin form circuits…”
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Efectos del entrenamiento en superficies inestables sobre el equilibrio y funcionalidad en adultos mayores
Published in Revista de la Facultad Nacional de Salud Pública (01-01-2015)“…Objetivo: determinar los efectos de un programa de ocho semanas de entrenamiento en superficies inestables con y sin trabajo de fuerza, sobre el equilibrio y…”
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Modeling serotonin 1A receptors in baboon and human subjects using the agonist tracer [ 11C]CUMI-101 and positron emission tomography
Published in NeuroImage (Orlando, Fla.) (2008)“…Here we report further evaluation of in vivo modeling options for [11C]MMP, now called [11C]CUMI-101 in both baboon and human subjects, including specificity,…”
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Biomarcadores para la evaluación de riesgo en la salud humana
Published in Revista de la Facultad Nacional de Salud Pública (13-06-2012)“…En el campo de la salud humana, el desarrollo, validación y uso de biomarcadores como herramientas de información para la evaluación de factores de riesgos…”
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