Search Results - "Arango, Margarita"
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Linking Mitochondria to Synapses: New Insights for Stress-Related Neuropsychiatric Disorders
Published in Neural plasticity (01-01-2016)“…The brain evolved cellular mechanisms for adapting synaptic function to energy supply. This is particularly evident when homeostasis is challenged by stress…”
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The Frequency of Porcine Cysticercosis and Factors Associated with Taenia solium Infection in the Municipality of Tuchín-Córdoba, Colombia
Published in Pathogens (Basel) (11-04-2024)“…Taeniasis and cysticercosis are parasitic infections that affect humans and pigs. Their global distribution constitutes a serious public health issue with…”
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Reversal of depressed behaviors in mice by p11 gene therapy in the nucleus accumbens
Published in Science translational medicine (20-10-2010)“…The etiology of major depression remains unknown, but dysfunction of serotonergic signaling has long been implicated in the pathophysiology of this disorder…”
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Cerebrovascular pathology during the progression of experimental Alzheimer's disease
Published in Neurobiology of disease (01-04-2016)“…Abstract Clinical and experimental evidence point to a possible role of cerebrovascular dysfunction in Alzheimer's disease (AD). The 5xFAD mouse model of AD…”
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Neurotrophic-priming of glucocorticoid receptor signaling is essential for neuronal plasticity to stress and antidepressant treatment
Published in Proceedings of the National Academy of Sciences - PNAS (22-12-2015)“…Neurotrophins and glucocorticoids are robust synaptic modifiers, and deregulation of their activities is a risk factor for developing stress-related disorders…”
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Topographic Reorganization of Cerebrovascular Mural Cells under Seizure Conditions
Published in Cell reports (Cambridge) (24-04-2018)“…Reorganization of the neurovascular unit has been suggested in the epileptic brain, although the dynamics and functional significance remain unclear. Here, we…”
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Cholinergic interneurons in the nucleus accumbens regulate depression-like behavior
Published in Proceedings of the National Academy of Sciences - PNAS (10-07-2012)“…A large number of studies have demonstrated that the nucleus accumbens (NAC) is a critical site in the neuronal circuits controlling reward responses,…”
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Dual imaging of dendritic spines and mitochondria in vivo reveals hotspots of plasticity and metabolic adaptation to stress
Published in Neurobiology of stress (01-11-2021)“…Metabolic adaptation is a critical feature of synaptic plasticity. Indeed, synaptic plasticity requires the utilization and resupply of metabolites, in…”
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Loss of glucocorticoid receptor phosphorylation contributes to cognitive and neurocentric damages of the amyloid-β pathway
Published in Acta neuropathologica communications (22-06-2022)“…Aberrant cortisol and activation of the glucocorticoid receptor (GR) play an essential role in age-related progression of Alzheimer's disease (AD). However,…”
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Gene therapy blockade of dorsal striatal p11 improves motor function and dyskinesia in parkinsonian mice
Published in Proceedings of the National Academy of Sciences - PNAS (02-02-2016)“…Complications of dopamine replacement for Parkinson’s disease (PD) can limit therapeutic options, leading to interest in identifying novel pathways that can be…”
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Cav3.2 T-type calcium channels shape electrical firing in mouse Lamina II neurons
Published in Scientific reports (28-02-2019)“…The T-type calcium channel, Cav3.2, is necessary for acute pain perception, as well as mechanical and cold allodynia in mice. Being found throughout sensory…”
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Resveratrol rescues mutant polyglutamine cytotoxicity in nematode and mammalian neurons
Published in Nature genetics (01-04-2005)“…We report that Sir2 activation through increased sir-2.1 dosage or treatment with the sirtuin activator resveratrol specifically rescued early neuronal…”
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13
Significados y respuestas de las madres al abuso sexual de sus hijas(os)
Published in Revista latinoamericana de ciencias sociales, niñez y juventud (2009)“…The goal of this research was to understand the meanings and responses that mothers of sexually abused children gave to this phenomenon, which could provide…”
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Integridad cognitiva y motora-sensorial en un niño con esquizencefalia de labio abierto unilateral derecho: reporte de caso
Published in Acta Neurológica Colombiana (01-01-2018)“…La esquizencefalia es una malformación poco común del sistema nervioso central, caracterizada por la presencia de hendiduras encefálicas que se extienden desde…”
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15
Timing and crosstalk of glucocorticoid signaling with cytokines, neurotransmitters and growth factors
Published in Pharmacological research (01-11-2016)“…[Display omitted] Glucocorticoid actions are tailored to the organs and cells responding thanks to complex integration with ongoing signaling mediated by…”
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Cerebellar dopamine D2 receptors regulate social behaviors
Published in Nature neuroscience (01-07-2022)“…The cerebellum, a primary brain structure involved in the control of sensorimotor tasks, also contributes to higher cognitive functions including reward,…”
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CA150 Expression Delays Striatal Cell Death in Overexpression and Knock-In Conditions for Mutant Huntingtin Neurotoxicity
Published in The Journal of neuroscience (26-04-2006)“…Transcriptional dysregulation caused by expanded polyglutamines (polyGlns) in huntingtin (htt) may be central to cell-autonomous mechanisms for neuronal cell…”
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Regeneration of the neurogliovascular unit visualized in vivo by transcranial live-cell imaging
Published in Journal of neuroscience methods (01-09-2020)“…•Multimodal transcranial in vivo imaging with cellular and temporal precision.•Longitudinal imaging of multicellular networks overtime to track…”
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Persistence of learning-induced synapses depends on neurotrophic priming of glucocorticoid receptors
Published in Proceedings of the National Academy of Sciences - PNAS (25-06-2019)“…Stress can either promote or impair learning and memory. Such opposing effects depend on whether synapses persist or decay after learning. Maintenance of new…”
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The Stress-Induced Transcription Factor NR4A1 Adjusts Mitochondrial Function and Synapse Number in Prefrontal Cortex
Published in The Journal of neuroscience (07-02-2018)“…The energetic costs of behavioral chronic stress are unlikely to be sustainable without neuronal plasticity. Mitochondria have the capacity to handle synaptic…”
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