Search Results - "Arancibia, Carolina"

The Short Chain Fatty Acid Butyrate Imprints an Antimicrobial Program in Macrophages by Schulthess, Julie, Pandey, Sumeet, Capitani, Melania, Rue-Albrecht, Kevin C., Arnold, Isabelle, Franchini, Fanny, Chomka, Agnieszka, Ilott, Nicholas E., Johnston, Daniel G.W., Pires, Elisabete, McCullagh, James, Sansom, Stephen N., Arancibia-Cárcamo, Carolina V., Uhlig, Holm H., Powrie, Fiona

“…Host microbial cross-talk is essential to maintain intestinal homeostasis. However, maladaptation of this response through microbial dysbiosis or defective…”
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Innate Lymphoid Cells in Intestinal Inflammation by Geremia, Alessandra, Arancibia-Cárcamo, Carolina V

“…Inflammatory bowel disease (IBD) is a chronic inflammatory disorder of the intestine that encompasses Crohn's disease (CD) and ulcerative colitis. The cause of…”
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TCR and Inflammatory Signals Tune Human MAIT Cells to Exert Specific Tissue Repair and Effector Functions by Leng, Tianqi, Akther, Hossain Delowar, Hackstein, Carl-Philipp, Powell, Kate, King, Thomas, Friedrich, Matthias, Christoforidou, Zoe, McCuaig, Sarah, Neyazi, Mastura, Arancibia-Cárcamo, Carolina V., Hagel, Joachim, Powrie, Fiona, Peres, Raphael Sanches, Millar, Val, Ebner, Daniel, Lamichhane, Rajesh, Ussher, James, Hinks, Timothy S.C., Marchi, Emanuele, Willberg, Chris, Klenerman, Paul

“…MAIT cells are an unconventional T cell population that can be activated through both TCR-dependent and TCR-independent mechanisms. Here, we examined the…”
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IL-23-responsive innate lymphoid cells are increased in inflammatory bowel disease by Geremia, Alessandra, Arancibia-Cárcamo, Carolina V, Fleming, Myles P P, Rust, Nigel, Singh, Baljit, Mortensen, Neil J, Travis, Simon P L, Powrie, Fiona

“…Results of experimental and genetic studies have highlighted the role of the IL-23/IL-17 axis in the pathogenesis of inflammatory bowel disease (IBD)…”
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Deletion of CTLA-4 on regulatory T cells during adulthood leads to resistance to autoimmunity by Paterson, Alison M, Lovitch, Scott B, Sage, Peter T, Juneja, Vikram R, Lee, Youjin, Trombley, Justin D, Arancibia-Cárcamo, Carolina V, Sobel, Raymond A, Rudensky, Alexander Y, Kuchroo, Vijay K, Freeman, Gordon J, Sharpe, Arlene H

“…Cytotoxic T lymphocyte antigen-4 (CTLA-4) is an essential negative regulator of T cell responses. Germline Ctla4 deficiency is lethal, making investigation of…”
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A functionally specialized population of mucosal CD103+ DCs induces Foxp3+ regulatory T cells via a TGF-beta and retinoic acid-dependent mechanism by Coombes, Janine L, Siddiqui, Karima R R, Arancibia-Cárcamo, Carolina V, Hall, Jason, Sun, Cheng-Ming, Belkaid, Yasmine, Powrie, Fiona

“…Foxp3(+) regulatory T (T reg) cells play a key role in controlling immune pathological re actions. Many develop their regulatory activity in the thymus, but…”
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Interleukin-23 Restrains Regulatory T Cell Activity to Drive T Cell-Dependent Colitis by Izcue, Ana, Hue, Sophie, Buonocore, Sofia, Arancibia-Cárcamo, Carolina V., Ahern, Philip P., Iwakura, Yoichiro, Maloy, Kevin J., Powrie, Fiona

“…Interleukin-23 (IL-23) is an inflammatory cytokine that plays a key role in the pathogenesis of several autoimmune and inflammatory diseases. It orchestrates…”
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Deconvolution of monocyte responses in inflammatory bowel disease reveals an IL-1 cytokine network that regulates IL-23 in genetic and acquired IL-10 resistance by Aschenbrenner, Dominik, Quaranta, Maria, Banerjee, Soumya, Ilott, Nicholas, Jansen, Joanneke, Steere, Boyd, Chen, Yin-Huai, Ho, Stephen, Cox, Karen, Arancibia-Cárcamo, Carolina V, Coles, Mark, Gaffney, Eamonn, Travis, Simon Pl, Denson, Lee, Kugathasan, Subra, Schmitz, Jochen, Powrie, Fiona, Sansom, Stephen N, Uhlig, Holm H

“…Dysregulated immune responses are the cause of IBDs. Studies in mice and humans suggest a central role of interleukin (IL)-23-producing mononuclear phagocytes…”
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A dynamic CD2-rich compartment at the outer edge of the immunological synapse boosts and integrates signals by Demetriou, Philippos, Abu-Shah, Enas, Valvo, Salvatore, McCuaig, Sarah, Mayya, Viveka, Kvalvaag, Audun, Starkey, Thomas, Korobchevskaya, Kseniya, Lee, Lennard Y. W., Friedrich, Matthias, Mann, Elizabeth, Kutuzov, Mikhail A., Morotti, Matteo, Wietek, Nina, Rada, Heather, Yusuf, Shamsideen, Afrose, Jehan, Siokis, Anastasios, Meyer-Hermann, Michael, Ahmed, Ahmed Ashour, Depoil, David, Dustin, Michael L.

“…The CD2–CD58 recognition system promotes adhesion and signaling and counters exhaustion in human T cells. We found that CD2 localized to the outer edge of the…”
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Extensive weight loss reduces glycan age by altering IgG N-glycosylation by Greto, Valentina L., Cvetko, Ana, Štambuk, Tamara, Dempster, Niall J., Kifer, Domagoj, Deriš, Helena, Cindrić, Ana, Vučković, Frano, Falchi, Mario, Gillies, Richard S., Tomlinson, Jeremy W., Gornik, Olga, Sgromo, Bruno, Spector, Tim D., Menni, Cristina, Geremia, Alessandra, Arancibia-Cárcamo, Carolina V., Lauc, Gordan

“…Background Obesity, a major global health problem, is associated with increased cardiometabolic morbidity and mortality. Protein glycosylation is a frequent…”
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Overexpression of Cancer-Associated Stem Cell Gene OLFM4 in the Colonic Epithelium of Patients With Primary Sclerosing Cholangitis by Neyazi, Mastura, Bharadwaj, Sraddha S, Bullers, Samuel, Varenyiova, Zofia, Travis, Simon, Arancibia-Cárcamo, Carolina V, Powrie, Fiona, Geremia, Alessandra

“…Abstract Background To examine immune-epithelial interactions and their impact on epithelial transformation in primary sclerosing cholangitis–associated…”
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Th1 and Innate Lymphoid Cells Accumulate in Primary Sclerosing Cholangitis-associated Inflammatory Bowel Disease by Gwela, Agnes, Siddhanathi, Priya, Chapman, Roger W, Travis, Simon, Powrie, Fiona, Arancibia-Cárcamo, Carolina V, Geremia, Alessandra

“…Abstract Background and Aims Primary sclerosing cholangitis [PSC] is an idiopathic chronic disorder of the hepatobiliary system associated with inflammatory…”
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Alterations in plasma protein N-glycosylation after caloric restriction and bariatric surgery by Štambuk, Tamara, Kifer, Domagoj, Greto, Valentina L., Dempster, Niall J., Cvetko, Ana, Gillies, Richard S., Tomlinson, Jeremy W., Sgromo, Bruno, Mineo, Chieko, Shaul, Philip W., Lauc, Gordan, Lingvay, Ildiko, Geremia, Alessandra, Arancibia-Cárcamo, Carolina V.

“…Protein glycosylation is an enzymatic process known to reflect an individual’s physiologic state and changes thereof. The impact of metabolic interventions on…”
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Epithelial immune activation and intracellular invasion by non-typeable Haemophilus influenzae by Brown, Mary A, Morgan, Sophie B, Donachie, Gillian E, Horton, Katie L, Pavord, Ian D, Arancibia-Cárcamo, Carolina V, Hinks, Timothy S C

“…Type-2 low asthma affects 30-50% of people with severe asthma and includes a phenotype characterized by sputum neutrophilia and resistance to corticosteroids…”
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Lymphocyte Activation Gene (LAG)-3 Is Associated With Mucosal Inflammation and Disease Activity in Ulcerative Colitis by Slevin, Stephanie M, Garner, Lucy C, Lahiff, Conor, Tan, Malcolm, Wang, Lai Mun, Ferry, Helen, Greenaway, Borgel, Lynch, Kate, Geremia, Alessandra, Hughes, Stephen, Leavens, Karen, Krull, David, Marks, Daniel J B, Nevin, Katherine, Page, Kevin, Srinivasan, Naren, Tarzi, Ruth, Klenerman, Paul, Travis, Simon, Arancibia-Cárcamo, Carolina V, Keshav, Satish

“…Abstract Background and Aims Lymphocyte activation gene [LAG]-3 is an immune checkpoint and its expression identifies recently activated lymphocytes that may…”
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Association between chronic periodontitis and herpes viruses: A review of the literature by Oñate, Héctor, Bravo, Alejandra, Arancibia, Carolina, Bustos, Paola, Cabrera, Karen

“…Objective: This research aims to analyze the available spe-cialized literature concerning the association between Herpesviruses [Cytomegalovirus (CMV), Epstein…”
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Auto-antibody production and glomerulonephritis in congenic Slamf1-/- and Slamf2-/- [B6.129] but not in Slamf1-/- and Slamf2-/- [BALB/c.129] mice by Keszei, Marton, Latchman, Yvette E, Vanguri, Vijay K, Brown, Daniel R, Detre, Cynthia, Morra, Massimo, Arancibia-Carcamo, Carolina V, Arancibia, Carolina V, Paul, Elahna, Calpe, Silvia, Castro, Wilson, Wang, Ninghai, Terhorst, Cox, Sharpe, Arlene H

“…Several genes in an interval of human and mouse chromosome 1 are associated with a predisposition for systemic lupus erythematosus. Congenic mouse strains that…”
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Tissue-dependent transcriptional and bacterial associations in primary sclerosing cholangitis-associated inflammatory bowel disease by Ilott, Nicholas E., Neyazi, Mastura, Arancibia-Cárcamo, Carolina V., Powrie, Fiona, Geremia, Alessandra

“…Background: Patients with primary sclerosing cholangitis (PSC) frequently have co-ocurring ulcerative colitis (UC) and develop colorectal cancer. Colorectal…”
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RORγt inhibitors suppress T(H)17 responses in inflammatory arthritis and inflammatory bowel disease by de Wit, Jelle, Al-Mossawi, M Hussein, Hühn, Michael H, Arancibia-Cárcamo, Carolina V, Doig, Karen, Kendrick, Benjamin, Gundle, Roger, Taylor, Peter, Mcclanahan, Terri, Murphy, Erin, Zhang, Hongjun, Barr, Ken, Miller, J Richard, Hu, Xiao, Aicher, Thomas D, Morgan, Rodney W, Glick, Gary D, Zaller, Dennis, Correll, Craig, Powrie, Fiona, Bowness, Paul

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Tissue-dependent transcriptional and bacterial associations in primary sclerosing cholangitis-associated inflammatory bowel disease by Ilott, Nicholas E, Neyazi, Mastura, Arancibia-Cárcamo, Carolina V, Powrie, Fiona, Geremia, Alessandra

“…Patients with primary sclerosing cholangitis (PSC) frequently have co-ocurring ulcerative colitis (UC) and develop colorectal cancer. Colorectal cancer risk in…”
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