Search Results - "Aramburu, Laura"

Methylsulfanylpyridine based diheteroaryl isocombretastatin analogs as potent anti-proliferative agents by Álvarez, Raquel, Aramburu, Laura, Gajate, Consuelo, Vicente-Blázquez, Alba, Mollinedo, Faustino, Medarde, Manuel, Peláez, Rafael

“…Isocombretastatins are the not isomerizable 1,1-diarylethene isomers of combretastatins. Both families of antimitotics are poorly soluble and new analogs with…”
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Potent colchicine-site ligands with improved intrinsic solubility by replacement of the 3,4,5-trimethoxyphenyl ring with a 2-methylsulfanyl-6-methoxypyridine ring by Álvarez, Raquel, Aramburu, Laura, Gajate, Consuelo, Vicente-Blázquez, Alba, Mollinedo, Faustino, Medarde, Manuel, Peláez, Rafael

“…[Display omitted] •Replacement of the 3,4,5-trimethoxyphenyl by 2-methylsulfanyl-6-methoxy-4-pyridyl leads to active analogues.•2,6-Dimethoxypyridine analogues…”
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Exploring the size adaptability of the B ring binding zone of the colchicine site of tubulin with para-nitrogen substituted isocombretastatins by Jiménez, Carmen, Ellahioui, Younes, Álvarez, Raquel, Aramburu, Laura, Riesco, Alejandra, González, Myriam, Vicente, Alba, Dahdouh, Abdelaziz, Ibn Mansour, Ahmed, Jiménez, Carlos, Martín, Diego, Sarmiento, Rogelio G., Medarde, Manuel, Caballero, Esther, Peláez, Rafael

“…We have synthesized and assayed dimethylaminophenyl, pyrrolidin-1-ylphenyl and carbazole containing phenstatins and isocombretastatins as analogues of the…”
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