Search Results - "Aramadhaka, Lavakumar Reddy"
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Endogenous concentrations of ouabain act as a cofactor to stimulate fluid secretion and cyst growth of in vitro ADPKD models via cAMP and EGFR-Src-MEK pathways
Published in American journal of physiology. Renal physiology (01-10-2012)“…In autosomal-dominant polycystic kidney disease (ADPKD), renal cysts develop by aberrant epithelial cell proliferation and transepithelial fluid secretion. We…”
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Loss of ADAM9 Leads to Modifications of the Extracellular Matrix Modulating Tumor Growth
Published in Biomolecules (Basel, Switzerland) (07-09-2020)“…ADAM9 is a metalloproteinase strongly expressed at the tumor-stroma border by both tumor and stromal cells. We previously showed that the host deletion of…”
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Connectivity maps for biosimilar drug discovery in venoms: The case of Gila Monster Venom and the anti-diabetes drug Byetta
Published in Toxicon (Oxford) (01-07-2013)“…Like most natural product libraries animal venoms have long been recognized as potentially rich source of biologically active molecules with the potential to…”
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Proteomic anatomy of human skin
Published in Journal of proteomics (12-06-2013)“…The extracellular matrix is composed of a variety of proteins which are essential for growth, wound healing, and fibrosis. It provides both structural support…”
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48. Use of Connectivity Maps and Platform Technologies for Drug Lead/Biosimilar Discovery in Venoms
Published in Toxicon (Oxford) (01-08-2012)Get full text
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Authors' response
Published in Journal of Clinical and Scientific Research (01-01-2019)Get full text
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