Search Results - "Aram, Lior"
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Structural evidence for extracellular silica formation by diatoms
Published in Nature communications (30-07-2021)“…The silica cell wall of diatoms, a widespread group of unicellular microalgae, is an exquisite example for the ability of organisms to finely sculpt minerals…”
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Intracellular morphogenesis of diatom silica is guided by local variations in membrane curvature
Published in Nature communications (10-09-2024)“…Silica cell-wall formation in diatoms is a showcase for the ability of organisms to control inorganic mineralization. The process of silicification by these…”
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Apoptosis is regulated by the VDAC1 N-terminal region and by VDAC oligomerization: release of cytochrome c, AIF and Smac/Diablo
Published in Biochimica et biophysica acta (01-06-2010)“…Mitochondria, central to basic life functions due to their generation of cellular energy, also serve as the venue for cellular decisions leading to apoptosis…”
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Exocytosis of the silicified cell wall of diatoms involves extensive membrane disintegration
Published in Nature communications (30-01-2023)“…Diatoms are unicellular algae characterized by silica cell walls. These silica elements are known to be formed intracellularly in membrane-bound silica…”
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A Krebs Cycle Component Limits Caspase Activation Rate through Mitochondrial Surface Restriction of CRL Activation
Published in Developmental cell (04-04-2016)“…How cells avoid excessive caspase activity and unwanted cell death during apoptotic caspase-mediated removal of large cellular structures is poorly understood…”
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VDAC1 cysteine residues: topology and function in channel activity and apoptosis
Published in Biochemical journal (01-05-2010)“…The VDAC (voltage-dependent anion channel) is proposed to control metabolic cross-talk between mitochondria and the cytosol, as well as apoptotic cell death…”
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The unconventional myosin CRINKLED and its mammalian orthologue MYO7A regulate caspases in their signalling roles
Published in Nature communications (10-03-2016)“…Caspases provide vital links in non-apoptotic regulatory networks controlling inflammation, compensatory proliferation, morphology and cell migration. How…”
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CDPs: caspase-dependent non-lethal cellular processes
Published in Cell death and differentiation (01-08-2017)Get full text
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Complex morphologies of biogenic crystals emerge from anisotropic growth of symmetry-related facets
Published in Science (American Association for the Advancement of Science) (15-04-2022)“…Directing crystal growth into complex morphologies is challenging, as crystals tend to adopt thermodynamically stable morphologies. However, many organisms…”
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Efficient gene replacement by CRISPR/Cas‐mediated homologous recombination in the model diatom Thalassiosira pseudonana
Published in The New phytologist (01-04-2023)“…Summary CRISPR/Cas enables targeted genome editing in many different plant and algal species including the model diatom Thalassiosira pseudonana. However,…”
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Sporoptosis: Sowing the Seeds of Nuclear Destruction
Published in Developmental cell (17-07-2012)“…What are the origins of programmed cell death (PCD)? In this issue of Developmental Cell, Eastwood et al. (2012) uncover an ancient developmental program of…”
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In situ electron microscopy characterization of intracellular ion pools in mineral forming microalgae
Published in Journal of structural biology (01-04-2020)“…The formation of coccoliths, intricate calcium carbonate scales that cover the cells of unicellular marine microalgae, is a highly regulated biological…”
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Surface-Induced Coacervation Facilitates Localized Precipitation of Mineral Precursors from Dilute Solutions
Published in Chemistry of materials (25-05-2021)“…Many organisms orchestrate the controlled precipitation of minerals. This physiological process takes place at ambient conditions, using soluble ions as…”
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14
The Mitochondria Limit the Rate of Caspase Activation During Spermatid Terminal Differentiation in Drosophila
Published 01-01-2016“…Partial cellular destruction during cell remodeling often involves active apoptotic caspases, but how cells avoid excessive caspase activity and unwanted cell…”
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Dissertation -
15
VDAC1 Cysteine Residues: Topology and Function in Channel Activity and Apoptosis
Published in Biophysical journal (01-01-2010)Get full text
Journal Article