Search Results - "Aram, Jalal A."

Post-hoc analysis of the safety and efficacy of isavuconazole in older patients with invasive fungal disease from the VITAL and SECURE studies by Hamed, Kamal, Engelhardt, Marc, Kovanda, Laura L., Huang, Jin Ju, Yan, Jean, Aram, Jalal A.

“…Isavuconazole is a triazole with broad-spectrum antifungal activity. In this post-hoc analysis of two prospective clinical trials (VITAL and SECURE), the…”
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Characterizing patients with rare mucormycosis infections using real-world data by Zhang, Yayue, Sung, Anita H, Rubinstein, Emily, Benigno, Michael, Chambers, Richard, Patino, Nataly, Aram, Jalal A

“…Invasive mucormycosis (IM) is a rare and often life-threatening fungal infection, for which clinical and epidemiological understanding is lacking. Electronic…”
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Effectiveness and safety of isavuconazole prophylaxis for invasive fungal infections in the haematologic setting by Ping, Yang, Hongmei, Jing, Bellmann, Christian, Inês, Mónica, Macmillan, Tom, Webb, Neil, Aram, Jalal A., Penack, Olaf

“…Patients with haematologic malignancies are at high risk of developing invasive fungal infections (IFIs). Current guidelines recommend the use of azoles for…”
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Utility of CT assessment in hematology patients with invasive aspergillosis: a post-hoc analysis of phase 3 data by Jin, Jie, Wu, Depei, Liu, Yang, Pan, Sisi, Yan, Jean Li, Aram, Jalal A, Lou, Yin-Jun, Meng, Haitao, Chen, Xiaochen, Zhang, Xian'an, Schwartz, Ilan S, Patterson, Thomas F

“…Pulmonary computed tomography (CT) scans are commonly used as part of the clinical criteria in diagnostic workup of invasive fungal diseases like invasive…”
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Efficacy and safety of rezafungin and caspofungin in candidaemia and invasive candidiasis: pooled data from two prospective randomised controlled trials by Thompson, George R, Soriano, Alex, Honore, Patrick M, Bassetti, Matteo, Cornely, Oliver A, Kollef, Marin, Kullberg, Bart Jan, Pullman, John, Hites, Maya, Fortún, Jesús, Horcajada, Juan P, Kotanidou, Anastasia, Das, Anita F, Sandison, Taylor, Aram, Jalal A, Vazquez, Jose A, Pappas, Peter G

“…Rezafungin, a new US Food and Drug Administration-approved, long-acting echinocandin to treat candidaemia and invasive candidiasis, was efficacious with a…”
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Outcomes by Candida spp. in the ReSTORE Phase 3 trial of rezafungin versus caspofungin for candidemia and/or invasive candidiasis by Locke, Jeffrey B, Pillar, Chris M, Castanheira, Mariana, Carvalhaes, Cecilia G, Andes, David, Aram, Jalal A, Andrzejewski, Christina, Bartizal, Ken, Das, Anita F, Sandison, Taylor, Thompson, 3rd, George R, Pappas, Peter G

“…Rezafungin is a long-acting, intravenously administered echinocandin for the treatment of candidemia and invasive candidiasis (IC). Non-inferiority of…”
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Risk factors in people with mold infections that have spread to different parts of the body: a plain language summary by Sung, Anita H, Martin, Stephan, Phan, Bryant, Benigno, Michael, Stephens, Jennifer, Aram, Jalal A

“…WHAT IS THIS SUMMARY ABOUT?This is a summary of a study originally published in ClinicoEconomics and Outcomes Research. Mold infections spread from one to…”
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Safety, Efficacy and Pharmacokinetics of Anidulafungin in Patients 1 Month to <2 Years of Age With Invasive Candidiasis, Including Candidemia by Roilides, Emmanuel, Carlesse, Fabianne, Tawadrous, Margaret, Leister-Tebbe, Heidi, Conte, Umberto, Raber, Susan, Swanson, Robert, Yan, Jean L., Aram, Jalal A., Queiroz-Telles, Flavio

“…Nineteen patients 1 month to <2 years of age with (n = 16) or at high risk of (n = 3) invasive candidiasis received anidulafungin for 5–35 days (3 mg/kg day 1,…”
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A plain language summary on preventing fungal infections with isavuconazole in people with blood-related conditions by Ping, Yang, Hongmei, Jing, Bellmann, Christian, Inês, Mónica, Macmillan, Tom, Webb, Neil, Aram, Jalal A, Penack, Olaf

“…WHAT IS THIS SUMMARY ABOUT?People with blood-related conditions have a higher chance of getting invasive fungal infections (IFIs). IFIs are severe fungal…”
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Evaluation of anidulafungin in the treatment of intra-abdominal candidiasis: a pooled analysis of patient-level data from 5 prospective studies by Sganga, Gabriele, Wang, Minggui, Capparella, M. Rita, Tawadrous, Margaret, Yan, Jean L., Aram, Jalal A., Montravers, Philippe

“…The incidence of nosocomial invasive fungal infections involving Candida spp. has increased markedly in recent years in patients undergoing abdominal surgery…”
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Invasive Candidiasis in Patients with Solid Tumors Treated with Anidulafungin: A Post Hoc Analysis of Efficacy and Safety of Six Pooled Studies by De Rosa, Francesco Giuseppe, Busca, Alessandro, Capparella, Maria Rita, Yan, Jean Li, Aram, Jalal A.

“…Background Solid tumors are a common predisposing factor for invasive candidiasis (IC) or candidemia due to IC. Objectives Post hoc analysis of patient-level…”
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Plain language summary: use of isavuconazole in Chinese patients with an invasive fungal disease by Zhang, Jing, Zhang, Yingyuan, Wu, Depei, Cao, Guoying, Hamed, Kamal, Desai, Amit, Aram, Jalal A, Guo, Xuan, Fayyad, Rana, Cornely, Oliver A

“…Invasive aspergillosis (also known as IA) is a type of fungal infection, caused by a species of fungus called , that can be life threatening. Isavuconazole and…”
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Clinical experience with isavuconazole in healthy volunteers and patients with invasive aspergillosis in China, and the results from an exposure–response analysis by Zhang, Jing, Zhang, Yingyuan, Wu, Depei, Cao, Guoying, Hamed, Kamal, Desai, Amit, Aram, Jalal A., Guo, Xuan, Fayyad, Rana, Cornely, Oliver A.

“…Background Isavuconazole is a broad‐spectrum triazole for the treatment of invasive fungal disease (IFD). Objective To investigate the clinical experience with…”
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Healthcare Resource Utilization and Discharge Readiness in Adult Hospitalized Patients With Candidemia or Invasive Candidiasis Who Received an Echinocandin: An Analysis of United States Hospitals by Lodise, Thomas P, Garey, Kevin W, Aram, Jalal A, Nathanson, Brian H

“…Scant real-world outcomes data are available among hospitalized patients with candidemia (C) or invasive candidiasis without candidemia (IC) who were treated…”
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A Prospective, Open-label Study to Assess the Safety, Tolerability and Efficacy of Anidulafungin in the Treatment of Invasive Candidiasis in Children 2 to <18 Years of Age by Roilides, Emmanuel, Carlesse, Fabianne, Leister-Tebbe, Heidi, Conte, Umberto, Yan, Jean L, Liu, Ping, Tawadrous, Margaret, Aram, Jalal A, Queiroz-Telles, Flavio

“…BACKGROUND:Treatment with an echinocandin is recommended as first-line therapy for patients with invasive candidiasis (ICC) including candidemia. Little is…”
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Study of an antifungal medicine isavuconazole used in treatment of mold infections in China: A plain language summary by Jing, Ran, Morrissey, Ian, Xiao, Meng, Sun, Tian-Shu, Zhang, Ge, Wei, Kang, Guo, Da-Wen, Aram, Jalal A, Wang, Jeffrey, Utt, Eric A, Wang, Yao, Xu, Ying-Chun

“…Molds are types of fungus that can cause sickness and death. Mold infections are increasing in China. Until 2022, medicines that can effectively treat all mold…”
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Safety, Efficacy, and Exposure–Response of Voriconazole in Pediatric Patients With Invasive Aspergillosis, Invasive Candidiasis or Esophageal Candidiasis by Martin, Judith M, Macias-Parra, Mercedes, Mudry, Peter, Conte, Umberto, Yan, Jean L, Liu, Ping, Capparella, M Rita, Aram, Jalal A

“…BACKGROUND:Data on safety and efficacy of voriconazole for invasive aspergillosis (IA) and invasive candidiasis/esophageal candidiasis (IC/EC) in pediatric…”
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Evaluation of the Effectiveness of Additional Risk Minimization Measures for Voriconazole in the EU: Findings and Lessons Learned from a Healthcare Professional Survey by Lem, Joanna, Younus, Muhammad, Aram, Jalal A., Moosavi, Shahrzad, Freivogel, Klaus, Lewis, Anne, Sobel, Rachel E.

“…Background Voriconazole is an extended-spectrum antifungal agent approved for the treatment and prophylaxis of invasive aspergillosis and other serious fungal…”
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Patient Characteristics and Risk Factors in Invasive Mold Infections: Comparison from a Systematic Review and Database Analysis by Sung, Anita H, Martin, Stephan, Phan, Bryant, Benigno, Michael, Stephens, Jennifer, Chambers, Richard, Aram, Jalal A

“…Diagnosis and treatment of invasive mold infections (IMI) can be challenging and IMI is a significant source of morbidity and mortality. Invasive aspergillosis…”
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Efficacy and safety of combination antifungal therapy in Korean haematological patients with invasive aspergillosis by Lee, Dong‐Gun, Lee, Hye‐Jung, Yan, Jean Li, Lin, Stephen Sheng‐Fong, Aram, Jalal A.

“…Summary This randomised, double‐blind, placebo‐controlled trial assessed the efficacy, safety and tolerability of voriconazole+anidulafungin (combination) or…”
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