Search Results - "Arakawa, Tatsuhiko"
-
1
Contribution of Leydig and Sertoli Cells to Testosterone Production in Mouse Fetal Testes
Published in Molecular endocrinology (Baltimore, Md.) (01-01-2013)“…Testosterone is a final product of androgenic hormone biosynthesis, and Leydig cells are known to be the primary source of androgens. In the mammalian testis,…”
Get full text
Journal Article -
2
GPAT2 is required for piRNA biogenesis, transposon silencing, and maintenance of spermatogonia in mice
Published in Biology of reproduction (01-07-2019)“…PIWI-interacting RNAs (piRNAs), a subclass of germ cell-specific noncoding small RNAs, are essential for de novo DNA methylation of retrotransposon genes in…”
Get full text
Journal Article -
3
Stella controls chromocenter formation through regulation of Daxx expression in 2-cell embryos
Published in Biochemical and biophysical research communications (09-10-2015)“…In mammals, the structure of the pericentromeric region alters from a ring structure to a dot-like structure during the 2-cell stage. This structural…”
Get full text
Journal Article -
4
Production of a monoclonal antibody specific for Pou5f1/Oct4
Published in Monoclonal antibodies in immunodiagnosis and immunotherapy (01-06-2013)“…Pou5f1/Oct4, a member of the POU transcription factor family, is exclusively expressed in embryonic stem cells, which are involved in self-renewal and…”
Get more information
Journal Article -
5
Stella preserves maternal chromosome integrity by inhibiting 5hmC-induced γH2AX accumulation
Published in EMBO reports (01-05-2015)“…In the mouse zygote, Stella/PGC7 protects 5‐methylcytosine (5mC) of the maternal genome from Tet3‐mediated oxidation to 5‐hydroxymethylcytosine (5hmC)…”
Get full text
Journal Article -
6
Perturbed hematopoiesis in individuals with germline DNMT3A overgrowth Tatton-Brown-Rahman syndrome
Published in Haematologica (Roma) (01-04-2022)“…Tatton-Brown-Rahman syndrome (TBRS) is an overgrowth disorder caused by germline heterozygous mutations in the DNA methyltransferase DNMT3A. DNMT3A is a…”
Get full text
Journal Article -
7
Expression of the Clustered NeuAcα2–3Galβ O-Glycan Determines the Cell Differentiation State of the Cells
Published in The Journal of biological chemistry (12-09-2014)“…Human embryonic stem cells (hESCs) are pluripotent stem cells from early embryos, and their self-renewal capacity depends on the sustained expression of…”
Get full text
Journal Article -
8
Stella preserves maternal chromosome integrity by inhibiting 5hmC‐induced γH2 AX accumulation
Published in EMBO reports (01-05-2015)Get full text
Journal Article -
9
Stella preserves maternal chromosome integrity by inhibiting 5hmC-induced [gamma]H2AX accumulation
Published in EMBO reports (01-05-2015)“…In the mouse zygote, Stella/PGC7 protects 5-methylcytosine (5mC) of the maternal genome from Tet3-mediated oxidation to 5-hydroxymethylcytosine (5hmC)…”
Get full text
Journal Article -
10
A novel marker for undifferentiated human embryonic stem cells
Published in Monoclonal antibodies in immunodiagnosis and immunotherapy (01-02-2015)“…Human embryonic stem cells (hESCs) are pluripotent stem cells from early embryos, and their self-renewal capacity depends on the sustained expression of…”
Get more information
Journal Article