Search Results - "Arakawa, Atsushi"

Microsatellite instability and mismatch repair protein expressions in lymphocyte‐predominant breast cancer by Horimoto, Yoshiya, Thinzar Hlaing, May, Saeki, Harumi, Kitano, Shigehisa, Nakai, Katsuya, Sasaki, Ritsuko, Kurisaki‐Arakawa, Aiko, Arakawa, Atsushi, Otsuji, Naomi, Matsuoka, Shuji, Tokuda, Emi, Arai, Masami, Saito, Mitsue

“…The frequency of microsatellite instability (MSI) is reportedly extremely low in breast cancer, despite widespread clinical expectations that many patients…”
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Abnormality of autophagic function and cathepsin expression in the liver from patients with non-alcoholic fatty liver disease by Fukuo, Yuka, Yamashina, Shunhei, Sonoue, Hiroshi, Arakawa, Atsushi, Nakadera, Eisuke, Aoyama, Tomonori, Uchiyama, Akira, Kon, Kazuyoshi, Ikejima, Kenichi, Watanabe, Sumio

“…Aim Recent evidences indicate that hepatic steatosis suppresses autophagic proteolysis. The present study evaluated the correlation between autophagic function…”
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Comparison of tumors with HER2 overexpression versus HER2 amplification in HER2-positive breast cancer patients by Horimoto, Yoshiya, Ishizuka, Yumiko, Ueki, Yuko, Higuchi, Toru, Arakawa, Atsushi, Saito, Mitsue

“…Human epidermal growth factor receptor 2 (HER2)-positive tumors are defined by protein overexpression (3+) or gene amplification using immunohistochemistry…”
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Phase IIa clinical study of [18F]fluciclovine: efficacy and safety of a new PET tracer for brain tumors by Kondo, Akihide, Ishii, Hisato, Aoki, Shigeki, Suzuki, Masaru, Nagasawa, Hidekazu, Kubota, Kazuo, Minamimoto, Ryogo, Arakawa, Atsushi, Tominaga, Masato, Arai, Hajime

“…Objective [ 18 F]Fluciclovine ( anti -[ 18 F]FACBC) has demonstrated diagnostic efficacy for cancers of the brain where [ 18 F]fludeoxyglucose has limitations…”
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ZNF671 DNA methylation as a molecular predictor for the early recurrence of serous ovarian cancer by Mase, Shoko, Shinjo, Keiko, Totani, Haruhito, Katsushima, Keisuke, Arakawa, Atsushi, Takahashi, Satoru, Lai, Hung‐Cheng, Lin, Ru‐Inn, Chan, Michael W. Y., Sugiura‐Ogasawara, Mayumi, Kondo, Yutaka

“…Serous ovarian cancer is the most frequent type of epithelial ovarian cancer. Despite the use of surgery and platinum‐based chemotherapy, many patients suffer…”
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Differences in Ki67 expressions between pre- and post-neoadjuvant chemotherapy specimens might predict early recurrence of breast cancer by Tokuda, Emi, MD, Horimoto, Yoshiya, MD, Arakawa, Atsushi, MD, Himuro, Takanori, MD, Senuma, Koji, MD, Nakai, Katsuya, MD, Saito, Mitsue, MD

“…The prognosis of breast cancer patients not obtaining a pathological complete response (pCR) with neoadjuvant chemotherapy (NAC) is poorer than that of pCR…”
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Combination of Cancer Stem Cell Markers CD44 and CD24 Is Superior to ALDH1 as a Prognostic Indicator in Breast Cancer Patients with Distant Metastases by Horimoto, Yoshiya, Arakawa, Atsushi, Sasahara, Noriko, Tanabe, Masahiko, Sai, Sei, Himuro, Takanori, Saito, Mitsue

“…The combination of CD44 and CD24, or aldehyde dehydrogenase 1 (ALDH1) alone, is a widely used cancer stem cell marker in breast cancer. However, no conclusion…”
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High platelet-to-lymphocyte ratios in triple-negative breast cancer associates with immunosuppressive status of TILs by Onagi, Hiroko, Horimoto, Yoshiya, Sakaguchi, Asumi, Ikarashi, Daiki, Yanagisawa, Naotake, Nakayama, Takayuki, Nakatsura, Tetsuya, Ishizuka, Yumiko, Sasaki, Ritsuko, Watanabe, Junichiro, Saito, Mitsue, Saeki, Harumi, Hayashi, Takuo, Arakawa, Atsushi, Yao, Takashi, Kitano, Shigehisa

“…Abstract Background Rating lymphocytes (TILs) are a prognostic marker in breast cancer and high TIL infiltration correlates with better patient outcomes…”
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Formation of p62‐positive inclusion body is associated with macrophage polarization in non‐alcoholic fatty liver disease by Fukushima, Hirofumi, Yamashina, Shunhei, Arakawa, Atsushi, Taniguchi, Gentaro, Aoyama, Tomonori, Uchiyama, Akira, Kon, Kazuyoshi, Ikejima, Kenichi, Watanabe, Sumio

“…Aim Hepatic inclusion composed of autophagy‐specific substrate p62 is one of the histological features of non‐alcoholic fatty liver disease (NAFLD) and can be…”
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High FOXA1 protein expression might predict late recurrence in patients with estrogen-positive and HER2-negative breast cancer by Horimoto, Yoshiya, Sasahara, Noriko, Sasaki, Ritsuko, Hlaing, May Thinzar, Sakaguchi, Asumi, Saeki, Harumi, Arakawa, Atsushi, Himuro, Takanori, Saito, Mitsue

“…Background Multi-gene expression assays have been developed with the aim of predicting late recurrence in patients with estrogen receptor (ER)-positive breast…”
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Molecular Characteristics of Lymphocyte-predominant Triple-negative Breast Cancer by Sasaki, Ritsuko, Horimoto, Yoshiya, Yanai, Yuka, Kurisaki-Arakawa, Aiko, Arakawa, Atsushi, Nakai, Katsuya, Saito, Mitsue, Saito, Tsuyoshi

“…Tumor-infiltrating lymphocytes (TILs) are considered a prognostic marker for triple-negative breast cancer (TNBC). Immune checkpoint inhibitor (ICI)-based…”
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Pembrolizumab monotherapy in Japanese patients with advanced ovarian cancer: Subgroup analysis from the KEYNOTE‐100 by Nishio, Shin, Matsumoto, Koji, Takehara, Kazuhiro, Kawamura, Naoki, Hasegawa, Kosei, Takeshima, Nobuhiro, Aoki, Daisuke, Kamiura, Shoji, Arakawa, Atsushi, Kondo, Eiji, Hirakawa, Tomoko, Yamamoto, Keiko, Aoki, Masayuki, Stein, Karen, Keefe, Stephen, Fujiwara, Keiichi, Ushijima, Kimio

“…Interim results from the two‐cohort, phase 2 KEYNOTE‐100 study (NCT02674061) of 376 patients with previously treated advanced recurrent ovarian cancer (ROC)…”
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Tamoxifen-resistant breast cancer cells exhibit reactivity with Wisteria floribunda agglutinin by Hlaing, May Thinzar, Horimoto, Yoshiya, Denda-Nagai, Kaori, Fujihira, Haruhiko, Noji, Miki, Kaji, Hiroyuki, Tomioka, Azusa, Ishizuka, Yumiko, Saeki, Harumi, Arakawa, Atsushi, Saito, Mitsue, Irimura, Tatsuro

“…Glycosylation is one of the most important post-translational modifications of cell surface proteins involved in the proliferation, metastasis and treatment…”
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Metastatic breast tumors from extramammary malignancies: a case series by Semba, Ryoko, Horimoto, Yoshiya, Arakawa, Atsushi, Saito, Mitsue

“…Background Metastatic breast tumors from extramammary malignancies are quite rare. Characteristics of such tumors are unclear due to small number of reported…”
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Biopsy Diagnosis of Hirschsprung's Disease Using a Single Excisional Biopsy Based on the Anorectal Line by Takeda, Masahiro, Ochi, Takanori, Koga, Hiroyuki, Tsuboi, Koichi, Arakawa, Atsushi, Lane, Geoffrey J, Yamataka, Atsuyuki

“…A biopsy protocol for diagnosing Hirschsprung's disease (HD) in children using the anorectal line (ARL).  The ARL was adopted for diagnosing HD in 2016 using…”
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A rare case of a toddler with unilateral cryptorchidism‐related cranial suspensory ligament remnant by Nakajima, Hideaki, Suda, Kazuto, Arakawa, Atsushi, Yanai, Toshihiro

“…Key clinical message Several animal experiment studies have shown that insufficient testicular descent to the scrotum can be caused by persistence of cranial…”
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Stromal Ki67 Expression Might be a Useful Marker for Distinguishing Fibroadenoma From Benign Phyllodes Tumor of the Breast by Yuan, Men, Saeki, Harumi, Horimoto, Yoshiya, Ishizuka, Yumiko, Onagi, Hiroko, Saito, Mitsue, Hayashi, Takuo, Arakawa, Atsushi, Yao, Takashi

“…Background. Fibroadenoma (FA) and benign phyllodes tumor (PT) of the breast often have similar appearances on imaging. While an exact diagnosis of biopsy…”
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Analysis of the risk factors and treatment for repeated implantation failure: OPtimization of Thyroid function, IMmunity, and Uterine Milieu (OPTIMUM) treatment strategy by Kuroda, Keiji, Matsumura, Yuko, Ikemoto, Yuko, Segawa, Tomoya, Hashimoto, Tomoko, Fukuda, Junichiro, Nakagawa, Koji, Uchida, Toyoyoshi, Ochiai, Asako, Horimoto, Yoshiya, Arakawa, Atsushi, Nojiri, Shuko, Itakura, Atsuo, Sugiyama, Rikikazu

“…Problem What are the pregnancy outcomes after the OPtimization of Thyroid function, Immunity, and Uterine Milieu (OPTIMUM) treatment strategy in patients with…”
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A Phase I clinical trial of carbon ion radiotherapy for Stage I breast cancer: clinical and pathological evaluation by Karasawa, Kumiko, Omatsu, Tokuhiki, Arakawa, Atsushi, Yamamoto, Naohito, Ishikawa, Takashi, Saito, Mitsue, Fukuda, Shigekazu, Kamada, Tadashi

“…Abstract Even with its high RBE and >20 years history, there had been no breast cancer clinical trial using carbon-ion radiotherapy. We started a Phase I trial…”
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Possible correlation of apical localization of MUC1 glycoprotein with luminal A-like status of breast cancer by Semba, Ryoko, Horimoto, Yoshiya, Sakata-Matsuzawa, Madoka, Ishizuka, Yumiko, Denda-Nagai, Kaori, Fujihira, Haruhiko, Noji, Miki, Onagi, Hiroko, Ichida, Miyu, Miura, Hiroyoshi, Watanabe, Junichiro, Saito, Mitsue, Saito, Tsuyoshi, Arakawa, Atsushi, Irimura, Tatsuro

“…Adjuvant chemotherapy has played a major role in the treatment of hormone receptor-positive breast cancer for many years. To better determine which patient…”
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