Search Results - "Arain, Taraq M"

Disparate Responses to Oxidative Stress in Saprophytic and Pathogenic Mycobacteria by Sherman, D R, Sabo, P J, Hickey, M J, Arain, T M, Mahairas, G G, Yuan, Y, Barry, 3rd, C E, Stover, C K

“…To persist in macrophages and in granulomatous caseous lesions, pathogenic mycobacteria must be equipped to withstand the action of toxic oxygen metabolites…”
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A small-molecule nitroimidazopyran drug candidate for the treatment of tuberculosis by Stover, C. Kendall, Warrener, Paul, VanDevanter, Donald R, Sherman, David R, Arain, Taraq M, Langhorne, Michael H, Anderson, Scott W, Towell, J. Andrew, Yuan, Ying, McMurray, David N, Kreiswirth, Barry N, Barry, Clifton E, Baker, William R

“…Mycobacterium tuberculosis, which causes tuberculosis, is the greatest single infectious cause of mortality worldwide, killing roughly two million people…”
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Compensatory ahpC Gene Expression in Isoniazid-Resistant Mycobacterium tuberculosis by Sherman, David R., Mdluli, Khisimuzi, Hickey, Mark J., Arain, Taraq M., Morris, Sheldon L., Barry, Clifton E., Stover, C. Kendall

“…Mutations that eliminate KatG catalase-peroxidase activity prevent activation of isoniazid and are a major mechanism of resistance to this principal drug for…”
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Luciferase in vivo expression technology: use of recombinant mycobacterial reporter strains to evaluate antimycobacterial activity in mice by HICKEY, M. J, ARAIN, T. M, SHAWAR, R. M, HUMBLE, D. J, LANGHORNE, M. H, MORGENROTH, J. N, STOVER, C. K

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Bioluminescence screening in vitro (Bio-Siv) assays for high-volume antimycobacterial drug discovery by ARAIN, T. M, RESCONI, A. E, HICKEY, M. J, STOVER, C. K

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Reporter gene technology to assess activity of antimycobacterial agents in macrophages by ARAIN, T. M, RESCONI, A. E, SINGH, D. C, STOVER, C. K

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Compensatory ahp C Gene Expression in Isoniazid-Resistant Mycobacterium tuberculosis by Sherman, David R., Mdluli, Khisimuzi, Hickey, Mark J., Arain, Taraq M., Morris, Sheldon L., Barry, Clifton E., Stover, C. Kendall

“…Mutations that eliminate KatG catalase-peroxidase activity prevent activation of isoniazid and are a major mechanism of resistance to this principal drug for…”
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Synergic activity of teicoplanin and ethambutol against Mycobacterium tuberculosis by Arain, T M, Goldstein, B P, Scotti, R, Resconi, A

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