Search Results - "Arai, Yoko"
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1
Prospects for Perinatal Mental Health Care
Published in The Kitakanto Medical Journal (01-05-2024)Get full text
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Neural Progenitor Cell Polarity and Cortical Development
Published in Frontiers in cellular neuroscience (05-12-2017)“…Neurons populating the cerebral cortex are generated during embryonic development from neural stem and progenitor cells in a process called neurogenesis…”
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Albendazole induces the terminal differentiation of acute myeloid leukaemia cells to monocytes by stimulating the Krüppel‐like factor 4‐dihydropyrimidinase‐like 2A (KLF4‐DPYSL2A) axis
Published in British journal of haematology (01-08-2021)“…Summary Differentiation therapy is a less toxic but still a very effective treatment for a subset of acute myeloid leukaemia (AML) cases. With the goal to…”
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Postnatal development of lymphatic vasculature in the brain meninges
Published in Developmental dynamics (01-05-2018)“…Background: Traditionally, the central nervous system (CNS) has been viewed as an immune‐privileged environment with no lymphatic vessels. This view was…”
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Inhibition of CDK4/6 and autophagy synergistically induces apoptosis in t(8;21) acute myeloid leukemia cells
Published in International journal of hematology (01-02-2021)“…The t(8;21) translocation is the most common cytogenetic abnormality in acute myeloid leukemia (AML). Although t(8;21) AML patients have a relatively favorable…”
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Pivotal role of DPYSL2A in KLF4-mediated monocytic differentiation of acute myeloid leukemia cells
Published in Scientific reports (20-11-2020)“…Although the biological importance of Krüppel-like factor 4 (KLF4) transcription factor in the terminal differentiation of hematopoietic cells to the monocytes…”
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Development and evolution of cortical fields
Published in Neuroscience research (01-09-2014)“…The neocortex is the brain structure that has been subjected to a major size expansion, in its relative size, during mammalian evolution. It arises from the…”
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Interneuron Development Is Disrupted in Preterm Brains With Diffuse White Matter Injury: Observations in Mouse and Human
Published in Frontiers in physiology (30-07-2019)“…Preterm brain injury, occurring in approximately 30% of infants born <32 weeks gestational age, is associated with an increased risk of neurodevelopmental…”
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Clinical characteristics and drug utilisation patterns in patients with chronic cough: a retrospective cohort study using a Japanese claims database
Published in BMC pulmonary medicine (21-11-2022)“…Although unmet medical needs for better care of patients with chronic cough exist in Japan, epidemiological information about these patients and their…”
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N-Acetylcysteine prevents amyloid-β secretion in neurons derived from human pluripotent stem cells with trisomy 21
Published in Scientific reports (30-08-2021)“…Down syndrome (DS) is caused by the trisomy of chromosome 21. Among the many disabilities found in individuals with DS is an increased risk of early-onset…”
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Migration Speed of Cajal-Retzius Cells Modulated by Vesicular Trafficking Controls the Size of Higher-Order Cortical Areas
Published in Current biology (05-10-2015)“…In the neocortex, higher-order areas are essential to integrate sensory-motor information and have expanded in size during evolution. How higher-order areas…”
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Mutations in mouse Aspm (abnormal spindle-like microcephaly associated) cause not only microcephaly but also major defects in the germline
Published in Proceedings of the National Academy of Sciences - PNAS (21-09-2010)“…Mutations in ASPM (abnormal spindle-like microcephaly associated) cause primary microcephaly in humans, a disorder characterized by a major reduction in brain…”
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13
Reallocation of Olfactory Cajal-Retzius Cells Shapes Neocortex Architecture
Published in Neuron (Cambridge, Mass.) (19-10-2016)“…The neocortex undergoes extensive developmental growth, but how its architecture adapts to expansion remains largely unknown. Here, we investigated how early…”
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Enhanced Abventricular Proliferation Compensates Cell Death in the Embryonic Cerebral Cortex
Published in Cerebral cortex (New York, N.Y. 1991) (01-10-2017)“…Loss of neurons in the neocortex is generally thought to result in a final reduction of cerebral volume. Yet, little is known on how the developing cerebral…”
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Effectiveness of prolonged exposure (PE) after implementation at a crime victim support centre
Published in European journal of psychotraumatology (2024)“…Recent practice guidelines strongly recommend evidence-based psychotherapies (EBPs) as the first-line treatment for post-traumatic stress disorder (PTSD)…”
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CXCR4 Overexpression is a Poor Prognostic Factor in Pediatric Acute Myeloid Leukemia With Low Risk: A Report From the Japanese Pediatric Leukemia/Lymphoma Study Group
Published in Pediatric blood & cancer (01-08-2016)“…Background Overexpression of CXC chemokine receptor 4 (CXCR4+) is a poor prognostic factor in adult acute myeloid leukemia (AML); however, its prognostic…”
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Effectiveness of trauma-focused cognitive behavioral therapy for Japanese children and adolescents in community settings: a multisite randomized controlled trial
Published in European journal of psychotraumatology (01-07-2020)“…Trauma-focused cognitive behavioural therapy (TF-CBT) is an efficacious treatment model for children and adolescents with trauma-related disorders. However,…”
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Evolutionary Gain of Dbx1 Expression Drives Subplate Identity in the Cerebral Cortex
Published in Cell reports (Cambridge) (15-10-2019)“…Changes in transcriptional regulation through cis-regulatory elements are thought to drive brain evolution. However, how this impacts the identity of primate…”
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Pluripotent stem cell model of early hematopoiesis in Down syndrome reveals quantitative effects of short-form GATA1 protein on lineage specification
Published in PloS one (29-03-2021)“…Children with Down syndrome (DS) are susceptible to two blood disorders, transient abnormal myelopoiesis (TAM) and Down syndrome-associated acute…”
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Editorial: In vivo Cell Biology of Cerebral Cortical Development and Its Related Neurological Disorders
Published in Frontiers in cellular neuroscience (21-06-2016)“…The aim of this research topic is to highlight important mechanisms underlying cerebral cortical development and associated neurological disorders, with a…”
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