Search Results - "Arai, Shinpei"

Neutrophil left shift and white blood cell count as markers of bacterial infection by Honda, Takayuki, Uehara, Takeshi, Matsumoto, Go, Arai, Shinpei, Sugano, Mitsutoshi

“…Neutrophil left shift and white blood cell (WBC) count are routine laboratory tests used to assess neutrophil state, which depends on supply from the bone…”
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A novel variant fibrinogen, AαE11del, demonstrating the importance of AαE11 residue in thrombin binding by Kaido, Takahiro, Yoda, Masahiro, Kamijo, Tomu, Arai, Shinpei, Yamauchi, Kazuyoshi, Okumura, Nobuo

“…Introduction We identified a novel heterozygous AαE11del variant in a patient with congenital dysfibrinogenemia. This mutation is located in fibrinopeptide A…”
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Recombinant γY278H Fibrinogen Showed Normal Secretion from CHO Cells, but a Corresponding Heterozygous Patient Showed Hypofibrinogenemia by Kamijo, Tomu, Kaido, Takahiro, Yoda, Masahiro, Arai, Shinpei, Yamauchi, Kazuyoshi, Okumura, Nobuo

“…We identified a novel heterozygous hypofibrinogenemia, γY278H (Hiroshima). To demonstrate the cause of reduced plasma fibrinogen levels (functional level: 1.12…”
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Novel variant fibrinogen γp.C352R produced hypodysfibrinogenemia leading to a bleeding episode and failure of infertility treatment by Yoda, Masahiro, Kaido, Takahiro, Kamijo, Tomu, Taira, Chiaki, Higuchi, Yumiko, Arai, Shinpei, Okumura, Nobuo

“…Introduction We identified a patient with a novel heterozygous variant fibrinogen, γp.C352R (Niigata II; N-II), who had a bleeding episode and failed…”
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Acquired dysfibrinogenemia: monoclonal λ-type IgA binding to fibrinogen caused lower functional plasma fibrinogen level and abnormal clot formation by Arai, Shinpei, Kamijo, Tomu, Takezawa, Yuka, Sugano, Mitsutoshi, Nakazawa, Hideyuki, Yanagisawa, Ryu, Uehara, Takeshi, Honda, Takayuki, Okumura, Nobuo

“…We report a case of acquired dysfibrinogenemia with monoclonal gammopathy of undetermined significance presenting λ -type IgA M protein. The patient showed…”
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A Novel Amino Acid Substitution, Fibrinogen Bβp.Pro234Leu, Associated with Hypofibrinogenemia Causing Impairment of Fibrinogen Assembly and Secretion by Kaido, Takahiro, Yoda, Masahiro, Kamijo, Tomu, Arai, Shinpei, Taira, Chiaki, Higuchi, Yumiko, Okumura, Nobuo

“…We identified a novel heterozygous variant, Bβp.Pro234Leu (fibrinogen Tokorozawa), which was suspected to be associated with hypofibrinogenemia. Therefore, we…”
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A Novel Mutation in the Fibrinogen Bβ Chain (c.490G>A; End of Exon 3) Causes a Splicing Abnormality and Ultimately Leads to Congenital Hypofibrinogenemia by Taira, Chiaki, Matsuda, Kazuyuki, Arai, Shinpei, Sugano, Mitsutoshi, Uehara, Takeshi, Okumura, Nobuo

“…We found a novel heterozygous mutation in the fibrinogen Bβ chain (c.490G>A) of a 3-year-old girl with congenital hypofibrinogenemia. To clarify the complex…”
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The fibrous form of intracellular inclusion bodies in recombinant variant fibrinogen-producing cells is specific to the hepatic fibrinogen storage disease-inducible variant fibrinogen by Arai, Shinpei, Ogiwara, Naoko, Mukai, Saki, Takezawa, Yuka, Sugano, Mitsutoshi, Honda, Takayuki, Okumura, Nobuo

“…Fibrinogen storage disease (FSD) is a rare disorder that is characterized by the accumulation of fibrinogen in hepatocytes and induces liver injury. Six…”
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γ375W fibrinogen-synthesizing CHO cells indicate the accumulation of variant fibrinogen within endoplasmic reticulum by Kobayashi, Tamaki, Arai, Shinpei, Ogiwara, Naoko, Takezawa, Yuka, Nanya, Mai, Terasawa, Fumiko, Okumura, Nobuo

“…Abstract Background Hepatic endoplasmic reticulum (ER) storage disease (HERSD) associated with hypofibrinogenemia has been reported in patients with four types…”
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Fibrin monomers derived from thrombogenic dysfibrinogenemia, Naples-type variant (BβAla68Thr), showed almost entirely normal polymerization by Kamijo, Tomu, Nagata, Kazuhiro, Taira, Chiaki, Higuchi, Yumiko, Arai, Shinpei, Okumura, Nobuo

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Progress in psychosocial therapy for schizophrenic patients and their families by Arai, Shinpei

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Polymorphism frequency of fibrinogen Bβ-chain 448Arg and Lys, and the differences of plasma fibrinogen level and clotting function with three genotypes in Japanese by Terasawa, Fumiko, Ikeda, Minami, Arai, Shinpei, Okumura, Nobuo

“…The 448th residue in the fibrinogen Bβ-chain molecule is known to be polymorphic (Arg/Lys, R/K), and its allele frequency was previously estimated to be R:…”
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A Case of Secondary Cryofibrinogenemia with Cholangiocarcinoma and Deep Venous Thrombosis by Arai, Shinpei, Sugano, Mitsutoshi, Honda, Takayuki, Kameko, Fumiko, Terasawa, Fumiko, Okumura, Nobuo

“…Cryofibrinogen (CF) is a type of cryoprotein (CP) that can precipitate in cooled plasma but not in serum, and resolves upon warming. We identified a case of…”
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Congenital dysfibrinogenemia coincidentally diagnosed at the onset of chronic myelogenous leukemia by Kirihara, Takehiko, Fujikawa, Yuko, Takeda, Wataru, Kurihara, Taro, Sato, Keijiro, Ueki, Toshimitsu, Hiroshima, Yuki, Sumi, Masahiko, Ueno, Mayumi, Ichikawa, Naoaki, Arai, Shinpei, Soya, Keisuke, Okumura, Nobuo, Kobayashi, Hikaru

“…A 34-year-old man was referred to our hospital for leukocytosis and fundal hemorrhage. Peripheral blood and coagulation tests showed increases in cells at all…”
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Congenital fibrinogen disorder with a compound heterozygote possessing two novel FGB mutations, one qualitative and the other quantitative by Yoda, Masahiro, Kaido, Takahiro, Taira, Chiaki, Higuchi, Yumiko, Arai, Shinpei, Okumura, Nobuo

“…Congenital fibrinogen disorders result from genetic mutations in FGA, FGB, or FGG resulting in quantitative fibrinogen deficiencies (afibrinogenemia or…”
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Automated screening procedure for the phenotypes of congenital fibrinogen disorders using novel parameters, |min1|c and Ac/|min1|c, obtained from clot waveform analysis using the Clauss method by Arai, Shinpei, Kamijo, Tomu, Kaido, Takahiro, Yoda, Masahiro, Shinohara, Sho, Suzuki, Takeshi, Arai, Nobuo, Sugano, Mitsutoshi, Uehara, Takeshi, Okumura, Nobuo

“…•Fibrinogen antigen is measured to classify congenital fibrinogen disorders (CFDs).•We developed the novel parameter, |min1|c, obtained from clot waveform…”
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Minimally invasive and inexpensive percutaneous abscess drainage using an indwelling needle cannula by Tanaka, Kumiko, Tsunoda, Atsunobu, Tou, Miri, Sonoda, Kenji, Arai, Shinpei, Anzai, Takashi, Matsumoto, Fumihiko

“…Abscess is still a formidable disease and requires adequate drainage. Moreover, drainage in the head and neck area needs cosmetic care, especially in the…”
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Emergency videoendoscopic endonasal tracheal intubation for severe upper airway stenosis by Tsunoda, Atsunobu, Kobayashi, Yuko, Tou, Miri, Sonoda, Kenji, Arai, Shinpei, Anzai, Takashi, Matsumoto, Fumihiko

“…Upper airway stenosis is one of the most formidable situations in medicine and is frequently encountered in the ENT clinic. We introduce here our method of…”
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A novel frameshift mutation in the fibrinogen γC terminal region, FGG c.1169_1170 del AT, leading to hypofibrinogenemia by Nagata, Kazuhiro, Arai, Shinpei, Taira, Chiaki, Sugano, Mitsutoshi, Honda, Takayuki, Okumura, Nobuo

“…•We encountered a novel hypofibrinogenemia patient.•The patient had a heterozygous nucleotide deletion with FGG c.1169_1170 del AT.•This resulted in a…”
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Genetic analyses of novel compound heterozygous hypodysfibrinogenemia, Tsukuba I: FGG c.1129 + 62_65 del AATA and FGG c.1299 + 4 del A by Mukai, Saki, Nagata, Kazuhiro, Ikeda, Minami, Arai, Shinpei, Sugano, Mitsutoshi, Honda, Takayuki, Okumura, Nobuo

“…Abstract Introduction We found a novel hypodysfibrinogenemia designated Tsukuba I caused by compound heterozygous nucleotide deletions with FGG c.1129 + 62_65…”
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