Search Results - "Arai, Ken"
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Recent updates on mechanisms of cell-cell interaction in oligodendrocyte regeneration after white matter injury
Published in Neuroscience letters (10-01-2020)“…•Promotion of remyelination process can be a novel therapeutic approach for CNS diseases.•Oligodendrocyte lineage cells receive trophic support from…”
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Integration of neurogenesis and angiogenesis models for constructing a neurovascular tissue
Published in Scientific reports (11-12-2017)“…Neurovascular unit (NVU) is a basic unit in the brain, including neurons, glial cells, blood vessels and extracellular matrix. This concept implies the…”
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Large Faraday effect in nanogranular films with a high refractive index matrix
Published in Optical materials express (01-02-2022)“…Nanogranular films consisting of a complex of nanometer-sized magnetic granules and a dielectric insulator matrix exhibit a large Faraday rotation. In this…”
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Exploring the novel role of oligodendrocyte precursor cells in phagocytosis: beyond myelinogenesis
Published in Neural regeneration research (01-02-2025)Get full text
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An Oligovascular Niche: Cerebral Endothelial Cells Promote the Survival and Proliferation of Oligodendrocyte Precursor Cells
Published in The Journal of neuroscience (08-04-2009)“…We show that cerebral endothelial cells secrete trophic factors that support the survival and proliferation of rat oligodendrocyte precursor cells (OPCs). This…”
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Mechanisms of cell–cell interaction in oligodendrogenesis and remyelination after stroke
Published in Brain research (14-10-2015)“…Abstract White matter damage is a clinically important aspect of several central nervous system diseases, including stroke. Cerebral white matter primarily…”
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Comparison of organ-specific endothelial cells in terms of microvascular formation and endothelial barrier functions
Published in Microvascular research (01-03-2019)“…Every organ demonstrates specific vascular characteristics and functions maintained by interactions of endothelial cells (ECs) and parenchymal cells…”
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Protective Effects of Endothelial Progenitor Cell‐Derived Extracellular Mitochondria in Brain Endothelium
Published in Stem cells (Dayton, Ohio) (01-09-2018)“…Endothelial progenitor cells (EPCs) have been pursued as a potential cellular therapy for stroke and central nervous system injury. However, their underlying…”
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Astrocytes Promote Oligodendrogenesis after White Matter Damage via Brain-Derived Neurotrophic Factor
Published in The Journal of neuroscience (14-10-2015)“…Oligodendrocyte precursor cells (OPCs) in the adult brain contribute to white matter homeostasis. After white matter damage, OPCs compensate for…”
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Crossed Anisotropy Multilayered Nanogranular Films Combining High Permeability, Ferromagnetic Resonance Frequency, and Resistivity
Published in IEEE transactions on magnetics (01-11-2023)“…In-plane isotropic crossed anisotropy multilayer for high-frequency magnetics was fabricated using in-plane uniaxial anisotropic nanogranular film owing to its…”
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Embodiment of supernumerary robotic limbs in virtual reality
Published in Scientific reports (27-06-2022)“…The supernumerary robotic limb system expands the motor function of human users by adding extra artificially designed limbs. It is important for us to embody…”
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Pathophysiologic cascades in ischemic stroke
Published in International Journal of Stroke (01-07-2012)“…Many advances have been achieved in terms of understanding the molecular and cellular mechanisms of ischemic stroke. But thus far, clinically effective…”
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Journal Article Book Review -
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A brief overview of a mouse model of cerebral hypoperfusion by bilateral carotid artery stenosis
Published in Journal of Cerebral Blood Flow & Metabolism (01-11-2023)“…Vascular cognitive impairment (VCI) refers to all forms of cognitive disorder related to cerebrovascular diseases, including vascular mild cognitive…”
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Book Review Journal Article -
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Molecular Mechanisms of Oligodendrocyte Regeneration in White Matter-Related Diseases
Published in International journal of molecular sciences (12-06-2018)“…Even in adult brains, restorative mechanisms are still retained to maintain the microenvironment. Under the pathological conditions of central nervous system…”
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Brain angiogenesis in developmental and pathological processes: neurovascular injury and angiogenic recovery after stroke
Published in The FEBS journal (01-09-2009)“…Pathophysiologic responses in brain after stroke are highly complex. Thus far, a singular focus on saving neurons alone has not revealed any clinically…”
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Three-Dimensional Blood-Brain Barrier Model for in vitro Studies of Neurovascular Pathology
Published in Scientific reports (27-10-2015)“…Blood–brain barrier (BBB) pathology leads to neurovascular disorders and is an important target for therapies. However, the study of BBB pathology is difficult…”
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Dual effects of carbon monoxide on pericytes and neurogenesis in traumatic brain injury
Published in Nature medicine (01-11-2016)“…In a mouse model of traumatic brain injury, treatment with a carbon-monoxide-releasing molecule is shown to reduce pericyte cell death and promote…”
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Effects of O-GlcNAcylation on functional mitochondrial transfer from astrocytes
Published in Journal of cerebral blood flow and metabolism (01-07-2021)“…Mitochondria may be transferred from cell to cell in the central nervous system and this process may help defend neurons against injury and disease. But how…”
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Rhythms in barriers and fluids: Circadian clock regulation in the aging neurovascular unit
Published in Neurobiology of disease (01-06-2023)“…The neurovascular unit is where two very distinct physiological systems meet: The central nervous system (CNS) and the blood. The permeability of the barriers…”
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Giant Faraday effect of FeCo‐BaF and FeCo‐SiN nanogranular films
Published in Electronics and communications in Japan (01-06-2021)“…We introduce FeCo‐BaF and FeCo‐SiN nanogranular films exhibiting giant Faraday effect. These films have a nanocomposite structure, in which nanometer‐sized…”
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