Search Results - "Aracena, Paula"

S-Glutathionylation Decreases Mg2+ Inhibition and S-Nitrosylation Enhances Ca2+ Activation of RyR1 Channels by Aracena, Paula, Sánchez, Gina, Donoso, Paulina, Hamilton, Susan L., Hidalgo, Cecilia

“…We have analyzed the effects of the endogenous redoxactive agents S-nitrosoglutathione and glutathione disulfide, and the NO donor NOR-3, on calcium release…”
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A Transverse Tubule NADPH Oxidase Activity Stimulates Calcium Release from Isolated Triads via Ryanodine Receptor Type 1 S -Glutathionylation by Hidalgo, Cecilia, Sánchez, Gina, Barrientos, Genaro, Aracena-Parks, Paula

“…We report here the presence of an NADPH oxidase (NOX) activity both in intact and in isolated transverse tubules and in triads isolated from mammalian skeletal…”
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Identification of Cysteines Involved in S-Nitrosylation, S-Glutathionylation, and Oxidation to Disulfides in Ryanodine Receptor Type 1 by Aracena-Parks, Paula, Goonasekera, Sanjeewa A., Gilman, Charles P., Dirksen, Robert T., Hidalgo, Cecilia, Hamilton, Susan L.

“…The skeletal muscle Ca2+-release channel (ryanodine receptor type 1 (RyR1)) is a redox sensor, susceptible to reversible S-nitrosylation, S-glutathionylation,…”
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Biological, Behavioral and Physiological Consequences of Drug-Induced Pregnancy Termination at First-Trimester Human Equivalent in an Animal Model by Camilleri, Christina, Beiter, Rebecca M, Puentes, Lisett, Aracena-Sherck, Paula, Sammut, Stephen

“…Given the significant physiological changes that take place during and resulting from pregnancy, as well as the relative absence of such information in…”
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Validation of a patient satisfaction survey of the Teleneurology program in Chile by Constanzo, Freddy, Aracena-Sherck, Paula, Hidalgo, Juan Pablo, Muñoz, Maritza, Vergara, Gerardo, Alvarado, Cristóbal

“…Telemedicine arises as an attractive intervention for reducing the waiting time for appointments with medical specialists in Chile. Successful implementation…”
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Contribution of a synchronic teleneurology program to decrease the patient number waiting for a first consultation and their waiting time in Chile by Constanzo, Freddy, Aracena-Sherck, Paula, Hidalgo, Juan Pablo, Peña, Lorena, Marrugo, Mery, Gonzalez, Jonathan, Vergara, Gerardo, Alvarado, Cristóbal

“…Backround There is a shortage of medical specialists in Chile, including neurologists; currently, there are 56,614 patients waiting for a first adult Neurology…”
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Characterization of the Teleneurology Patients at the Hospital Las Higueras de Talcahuano-Chile by Constanzo, Freddy, Aracena-Sherck, Paula, Peña, Lorena, Marrugo, Mery, Gonzalez, Jonathan, Vergara, Gerardo, Alvarado, Cristóbal

“…Chile has a shortage of medical experts, including neurologists. The remote neurology program at Las Higueras Hospital in Talcahuano (HHT) was implemented in…”
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Iron and glutathione at the crossroad of redox metabolism in neurons by Aracena, Paula, Aguirre, Pabla, Muñoz, Pablo, Núñez, Marco T

“…Neurons, as non-dividing cells, encounter a myriad of stressful conditions throughout their lifespan. In particular, there is increasing evidence that iron…”
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Redox regulation of calcium release in skeletal and cardiac muscle by Hidalgo, Cecilia, Aracena, Paula, Sanchez, Gina, Donoso, Paulina

“…In skeletal and cardiac muscle cells, specific isoforms of the Ryanodine receptor channels mediate Ca2+ release from the sarcoplasmic reticulum. These channels…”
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l-NIL prevents the ischemia and reperfusion injury involving TLR-4, GST, clusterin, and NFAT-5 in mice by Pasten, Consuelo, Alvarado, Cristóbal, Rocco, Jocelyn, Contreras, Luis, Aracena, Paula, Liberona, Jéssica, Suazo, Cristian, Michea, Luis, Irarrázabal, Carlos E

“…On renal ischemia-reperfusion (I/R) injury, recruitment of neutrophils during the inflammatory process promotes local generation of oxygen and nitrogen…”
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Effects of S-glutathionylation and S-nitrosylation on calmodulin binding to triads and FKBP12 binding to type 1 calcium release channels by Aracena, Paula, Tang, Wei, Hamilton, Susan L, Hidalgo, Cecilia

“…This study shows that the combination of glutathione (GSH) plus hydrogen peroxide (H2O2) promotes the S-glutathionylation of ryanodine receptor type 1 (RyR1)…”
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Microsomal oxidative damage promoted by acetaminophen metabolism by Letelier, María Eugenia, López-Valladares, Miguel, Peredo-Silva, Liliana, Rojas-Sepúlveda, Daniel, Aracena, Paula

“…► Rat liver microsomes contain a NADPH oxidase (NOX) activity. ► Acetaminophen and NADPH generate ROS through this NOX activity. ► NAPQI rather than ROS…”
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Abortion legislation, maternal healthcare, fertility, female literacy, sanitation, violence against women and maternal deaths: a natural experiment in 32 Mexican states by Koch, Elard, Chireau, Monique, Pliego, Fernando, Stanford, Joseph, Haddad, Sebastian, Calhoun, Byron, Aracena, Paula, Bravo, Miguel, Gatica, Sebastián, Thorp, John

“…Objective To test whether there is an association between abortion legislation and maternal mortality outcomes after controlling for other factors thought to…”
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Maternal health is better where abortion is restricted: analysis of a decade of Mexican data shows the opposite of what is regularly claimed by Aracena, Paula

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Possible mechanisms underlying copper-induced damage in biological membranes leading to cellular toxicity by Letelier, María Eugenia, Lepe, Ana María, Faúndez, Mario, Salazar, Julia, Marín, Rigoberto, Aracena, Paula, Speisky, Hernán

“…It is generally accepted that copper toxicity is a consequence of the generation of reactive oxygen species (ROS) by copper ions via Fenton or Haber–Weiss…”
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Regulation of voltage-gated Ca2+ channels by calmodulin by Halling, D Brent, Aracena-Parks, Paula, Hamilton, Susan L

“…Calmodulin, a highly versatile and ubiquitously expressed Ca2+ sensor, regulates the function of many enzymes and ion channels. Both Ca2+-dependent…”
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Microsomal UDP‐Glucuronyltransferase in Rat Liver: Oxidative Activation by Letelier, María Eugenia, Pimentel, Alejandra, Pino, Patricia, Lepe, Ana María, Faúndez, Mario, Aracena, Paula, Speisky, Hernán

“…: Activation of microsomal UDP‐glucuronyltransferase (UDPGT) activity by treatment of hepatic microsomes with either detergents or Fe3+/ascorbate pro‐oxidant…”
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Fundamental discrepancies in abortion estimates and abortion-related mortality: A reevaluation of recent studies in Mexico with special reference to the International Classification of Diseases by Koch, Elard, Aracena, Paula, Gatica, Sebastián, Bravo, Miguel, Huerta-Zepeda, Alejandra, Calhoun, Byron C

“…In countries where induced abortion is legally restricted, as in most of Latin America, evaluation of statistics related to induced abortions and…”
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Mechanisms underlying iron and copper ions toxicity in biological systems: Pro-oxidant activity and protein-binding effects by Letelier, María Eugenia, Sánchez-Jofré, Sebastián, Peredo-Silva, Liliana, Cortés-Troncoso, Juan, Aracena-Parks, Paula

“…Iron and copper ions, in their unbound form, may lead to the generation of reactive oxygen species via Haber–Weiss and/or Fenton reactions. In addition, it has…”
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Sulfhydryl Oxidation Overrides Mg2+ Inhibition of Calcium-Induced Calcium Release in Skeletal Muscle Triads by Donoso, Paulina, Aracena, Paula, Hidalgo, Cecilia

“…We studied the effect of oxidation of sulfhydryl (SH) residues on the inhibition by Mg2+ of calcium-induced calcium release (CICR) in triad-enriched…”
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