Search Results - "Arab, Tanina"
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Characterization of extracellular vesicles and synthetic nanoparticles with four orthogonal single‐particle analysis platforms
Published in Journal of extracellular vesicles (01-04-2021)“…We compared four orthogonal technologies for sizing, counting, and phenotyping of extracellular vesicles (EVs) and synthetic particles. The platforms were:…”
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Neutral sphingomyelinase 2 inhibition attenuates extracellular vesicle release and improves neurobehavioral deficits in murine HIV
Published in Neurobiology of disease (01-07-2022)“…People living with HIV (PLH) have significantly higher rates of cognitive impairment (CI) and major depressive disorder (MDD) versus the general population…”
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Characterization of spinal cord tissue-derived extracellular vesicles in neuroinflammation
Published in Journal of neuroinflammation (08-06-2024)“…Extracellular vesicles (EVs) are released by all cells, can cross the blood-brain barrier, and have been shown to play an important role in cellular…”
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Isolation of microglia-derived extracellular vesicles: towards miRNA signatures and neuroprotection
Published in Journal of nanobiotechnology (04-12-2019)“…The functional preservation of the central nervous system (CNS) is based on the neuronal plasticity and survival. In this context, the neuroinflammatory state…”
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Medicinal Leech CNS as a Model for Exosome Studies in the Crosstalk between Microglia and Neurons
Published in International journal of molecular sciences (19-12-2018)“…In healthy or pathological brains, the neuroinflammatory state is supported by a strong communication involving microglia and neurons. Recent studies indicate…”
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ALK4/5-dependent TGF-β signaling contributes to the crosstalk between neurons and microglia following axonal lesion
Published in Scientific reports (03-05-2019)“…Neuronal activity is closely influenced by glia, especially microglia which are the resident immune cells in the central nervous system (CNS). Microglia in…”
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Toward a human brain extracellular vesicle atlas: Characteristics of extracellular vesicles from different brain regions, including small RNA and protein profiles
Published in Interdisciplinary medicine (Richmond, Vic. Print) (01-10-2023)“…Extracellular vesicles (EVs) are released from different cell types in the central nervous system (CNS) and play roles in regulating physiological and…”
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Brain Tissue-Derived Extracellular Vesicles in Alzheimer's Disease Display Altered Key Protein Levels Including Cell Type-Specific Markers
Published in Journal of Alzheimer's disease (01-01-2022)“…Brain tissue-derived extracellular vesicles (bdEVs) play neurodegenerative and protective roles, including in Alzheimer's disease (AD). Extracellular vesicles…”
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Exosomes, microvesicles, and other extracellular vesicles—a Keystone Symposia report
Published in Annals of the New York Academy of Sciences (01-05-2023)“…Extracellular vesicles (EVs) are small, lipid‐bilayer‐bound particles released by cells that can contain important bioactive molecules, including lipids, RNAs,…”
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Relationships of APOE Genotypes With Small RNA and Protein Cargo of Brain Tissue Extracellular Vesicles From Patients With Late-Stage AD
Published in Neurology. Genetics (01-12-2022)“…Variants of the apolipoprotein E gene are the greatest known risk factors for sporadic Alzheimer disease (AD). Three major isoform alleles, , and , encode and…”
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Study of exosomal microRNAs from microglia involved in neuroprotection in Hirudo medicinalis
Published in Journal of extracellular vesicles (01-01-2018)“…Background: Unlike vertebrates, the medicinal leech (Hirudo medicinalis) can be lesioned only on axons without any contact on neuronal cell bodies due to the…”
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